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The role of RNA capping of SARS-CoV-2 in immunity evasion

The SARS-CoV-2 pathogen successfully uses multiple immune evasion mechanisms to achieve infection within its host. An intriguing new study describes one such process, which may help develop drugs to counteract the virus more effectively.

16 Mar 2021

New study tests how mutations in SARS-CoV-2 affect antibody neutralization

Using pseudoviruses with single amino acid substitutions, researchers found that mutations in SARS-CoV-2 reduce monoclonal antibody neutralization differently. However, convalescent sera samples did not lose neutralization potency many and were also effective against the B.1.1.7 (UK-derived) strain.

16 Mar 2021

Engineered mouse Intestine Chip platform can help study host-microbiome interactions

Trillions of commensal microbes live on the mucosal and epidermal surfaces of the body and it is firmly established that this microbiome affects its host's tolerance and sensitivity of the host to a variety of pathogens.

16 Mar 2021

UAB researchers find potential new pathway to treating radiation-resistant glioblastoma

Researchers at the University of Alabama at Birmingham have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer.

15 Mar 2021

New cancer immunotherapy uses engineered T cells to target a common genetic alteration

Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.

15 Mar 2021

Scientists discover how novel pathogens promote colorectal cancer development

Do BMMFs, the novel infectious agents found in dairy products and bovine sera, play a role in the development of colorectal cancer? Scientists led by Harald zur Hausen detected the pathogens in colorectal cancer patients in close proximity to tumors.

15 Mar 2021

Exercise during pregnancy can disrupt the vicious cycle of parents-to-child transmission of diseases

Exercise during pregnancy may let mothers significantly reduce their children's chances of developing diabetes and other metabolic diseases later in life, new research suggests.

15 Mar 2021

HPSE protein found to be a key regulator of cells’ innate defense mechanisms

Researchers at the University of Illinois Chicago have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells' innate defense mechanisms.

15 Mar 2021

Researchers find no evidence to suggest a link between beta blockers and depression

Drugs such as beta-adrenergic antagonists (beta blockers) have been linked to a range of adverse effects, including depression.

15 Mar 2021

Study uncovers how the brain learns from subconscious stimuli

Researchers uncovered for the first time what happens in animals' brains when they learn from subconscious, visual stimuli. In time, this knowledge can lead to new treatments for a number of conditions.

15 Mar 2021

Discovery may help cancer patients to avoid chemotherapy's debilitating side effects

A discovery by University of Queensland pain researchers may allow some future cancer patients, including children with leukemia, to avoid their chemotherapy's worst and most debilitating side effects.

15 Mar 2021

Non-traditional shift work schedules lead to higher rates of kidney disruption and injury

A disruption to organ rhythms caused by shift work is a key factor in injury-induced disease development, according to a new research article published in the America Journal of Physiology-Renal Physiology.

15 Mar 2021

Researchers use wastewater to monitor prevalence of COVID-19 for first time in United Arab Emirates

Early warning systems are vital in preventing surging waves of the coronavirus disease 2019 (COVID-19) pandemic. Researchers have used wastewater samples to detect the spread of the virus in the United Arab Emirates from municipal and commercial aircraft, the first of its kind in the country, and the largest to date.

15 Mar 2021

White-tailed deer susceptible to SARS-CoV-2, finds study

White-tailed deer have been observed to be susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They can also transmit the virus both through direct and indirect contact to one another, researchers find. The research paper is available to be read online in the Journal of Virology.

15 Mar 2021

The role of nanotechnology in the fight against COVID-19

Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse nanomaterials (polymeric, inorganic self-assembling materials and peptide-based) towards COVID-19 prevention, diagnosis and therapy.

15 Mar 2021

What is a protective neutralizing antibody titer against SARS-CoV-2 infection?

A new study describes a predictive model of protective immunity against SARS-CoV-2 infection that could help evolve optimal vaccination strategies to maintain protection and reduce the death rate.

15 Mar 2021

Why does convalescent plasma therapy for severe COVID-19 show mixed success?

A surprising new preprint, released on the medRxiv* server, suggests that the beneficial effects of convalescent plasma (CP) in this disease stem not only from the presence of neutralizing antibodies, but also the immunomodulatory effects of this plasma that shapes the host immune response.

15 Mar 2021

Which biomarkers can help predict severe COVID-19?

The ability to detect potentially fatal illness early on in the course of the disease would enable a swift prioritization of these high-risk individuals for treatment. A new preprint on the medRxiv* server presents an array of biomarkers that may help achieve this laudable goal.

15 Mar 2021

Neutralizing nanobodies effective against SARS-CoV-2 variants

Nanobodies have different mechanisms to neutralize viruses, and some target epitopes not accessible to monoclonal antibodies, making them an alternative for developing therapies for COVID-19.

15 Mar 2021

Study suggests COVID-19 vaccine acceptance on the rise in UK

A team of researchers in the UK recently conducted a two-wave survey on the hesitancy of individuals to receive COVID-19 vaccination.

15 Mar 2021

Medical Science News

The role of RNA capping of SARS-CoV-2 in immunity evasion

New study tests how mutations in SARS-CoV-2 affect antibody neutralization

Engineered mouse Intestine Chip platform can help study host-microbiome interactions

UAB researchers find potential new pathway to treating radiation-resistant glioblastoma

New cancer immunotherapy uses engineered T cells to target a common genetic alteration

Scientists discover how novel pathogens promote colorectal cancer development

Exercise during pregnancy can disrupt the vicious cycle of parents-to-child transmission of diseases

HPSE protein found to be a key regulator of cells’ innate defense mechanisms

Researchers find no evidence to suggest a link between beta blockers and depression

Study uncovers how the brain learns from subconscious stimuli

Discovery may help cancer patients to avoid chemotherapy's debilitating side effects

Non-traditional shift work schedules lead to higher rates of kidney disruption and injury

Researchers use wastewater to monitor prevalence of COVID-19 for first time in United Arab Emirates

White-tailed deer susceptible to SARS-CoV-2, finds study

The role of nanotechnology in the fight against COVID-19

What is a protective neutralizing antibody titer against SARS-CoV-2 infection?

Why does convalescent plasma therapy for severe COVID-19 show mixed success?

Which biomarkers can help predict severe COVID-19?

Neutralizing nanobodies effective against SARS-CoV-2 variants

Study suggests COVID-19 vaccine acceptance on the rise in UK

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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