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A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

Researchers found that cetylpyridinium chloride, found in most mouthwashes, lowers infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro, likely by inhibiting viral fusion with target cells. With more tests to prove validity, mouthwashes could be a simple, cheap way of curbing transmission.

24 Dec 2020

Researchers review future directions of nanomedicine development

Announcing a new publication for BIO Integration journal. In this commentary the authors Phei Er Saw and Sangyong Jon from Sun Yat-Sen University, Guangzhou, China and the Korea Advanced Institute of Science and Technology, Daejeon, Korea, consider how the entry mechanism of nanoparticles into tumors determines the future direction of nanomedicine development.

24 Dec 2020

Study shows how human brains navigate physical space and keep track of others' location

For the first time, scientists have recorded how our brains navigate physical space and keep track of others' location. Researchers used a special backpack to wirelessly monitor the brain waves of epilepsy patients as each one walked around an empty room hunting for a hidden, two-foot spot.

24 Dec 2020

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.

24 Dec 2020

Miniature pH probe allows real-time analysis of pH dynamics in deep brain structures

Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.

24 Dec 2020

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell.

24 Dec 2020

New tool may help monitor serotonin transmission with greater fidelity than current methods

Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings.

23 Dec 2020

Study reveals how our brains track where we and others go

As COVID cases rise, physically distancing yourself from other people has never been more important. Now a new UCLA study reveals how your brain navigates places and monitors someone else in the same location.

23 Dec 2020

Research demonstrates new mechanisms to control dental procedure spray emissions

Since the onset of COVID-19 the potential risk of dental procedure spray emissions for SARS-CoV-2 transmission has challenged care providers and policy makers alike.

23 Dec 2020

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

A team of scientists from the Centers for Disease Control and Prevention, United States, recently conducted a study to evaluate the effectiveness of serial testing and isolation of healthcare personnel in nursing homes in preventing the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Dec 2020

Public adherence to COVID-19 guidelines in Norway: a case study

To evaluate and understand the adherence to public health actions recommended by the government, a team in Norway undertook a study funded in part by the Norwegian Research Council’s Centres of Excellence Funding Scheme and by the project: A realtime analytical pipeline for preparedness, planning, and response during the COVID-19 pandemic in Norway.

23 Dec 2020

Genetic analysis reveals novel traits associated with COVID-19 severity

Researchers in the United States have conducted genetic correlation studies revealing novel traits associated with the development of severe coronavirus disease 2019 (COVID-19).

23 Dec 2020

First UK lockdown during COVID-19 pandemic negatively impacted dementia care

Researchers in the United Kingdom have conducted an extensive survey exploring the impact that lockdown had on people living with low prevalence and young-onset dementias during the first wave of the coronavirus disease 2019 (COVID-19) pandemic.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Novel computational tool can systematically analyze cell images in C. elegans

A joint research team co-led by City University of Hong Kong (CityU) has developed a novel computational tool that can reconstruct and visualise three-dimensional (3D) shapes and temporal changes of cells, speeding up the analysing process from hundreds of hours by hand to a few hours by the computer.

23 Dec 2020

Changes in consciousness linked to the same brain network for sleep and anesthesia

The loss and return of consciousness is linked to the same network of brain regions for both sleep and anesthesia, according to new research published in JNeurosci.

23 Dec 2020

Medical Science News

A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

Researchers review future directions of nanomedicine development

Study shows how human brains navigate physical space and keep track of others' location

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Miniature pH probe allows real-time analysis of pH dynamics in deep brain structures

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

New tool may help monitor serotonin transmission with greater fidelity than current methods

Study reveals how our brains track where we and others go

Research demonstrates new mechanisms to control dental procedure spray emissions

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

Public adherence to COVID-19 guidelines in Norway: a case study

Genetic analysis reveals novel traits associated with COVID-19 severity

First UK lockdown during COVID-19 pandemic negatively impacted dementia care

SARS-CoV-2 mutations may evade T cell immunity

COVID-19 severity could be linked to genetic variance

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

Novel computational tool can systematically analyze cell images in C. elegans

Changes in consciousness linked to the same brain network for sleep and anesthesia

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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