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Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

17 Dec 2020

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

The ASH Research Collaborative and the International Society of Haemostasis and Thrombosis, two organizations with multidisciplinary expertise in blood clotting and bleeding disorders, have developed a toolkit to help clinical researchers from across medical disciplines design clinical trials that further the understanding of blood clotting events associated with COVID-19.

17 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

Fish oil supplements not associated with increases in bad cholesterol

The Fatty Acid Research Institute has published a new research paper in conjunction with The Cooper Institute on the omega-3s EPA and DHA in fish oil and low density lipoprotein cholesterol (LDL-C).

17 Dec 2020

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

Female COVID-19 patients face less severe disease complications and a lower risk of dying than male patients thanks to hormones and chromosomes that contribute to a stronger immune response, according to new research from a University of Alberta-led team.

17 Dec 2020

PVP at Boston Children's awarded $1 million to extend research into adjuvant-based vaccines

For a vaccine to be most effective, sometimes nature needs a little 'extra' something. That something is often an adjuvant -- small molecules added to a vaccine that boost the body's immune response.

17 Dec 2020

Researchers highlight the need to renew understanding of adverse events in interventional radiology

Medical errors pose a serious threat to patient safety and are estimated to account for more than 250,000 deaths in the U.S. each year.

17 Dec 2020

Errant DNA triggers immune system response against cancer

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

17 Dec 2020

WEHI researchers suggest potential new approach to treat stomach cancer

WEHI researchers have identified a key molecular regulator involved in the progression and spread of stomach cancer, suggesting a potential new approach to treat this devastating disease.

17 Dec 2020

How does the UK’s COVID-19 response compare to others in Europe?

Researchers modeled the health benefits and economic loss caused by coronavirus disease 2019 (COVID-19) in the UK and compared them to four other western European countries. Their results suggest the British Government’s response may outweigh the economic loss incurred.

17 Dec 2020

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

A new study by researchers at the Karolinska University Hospital in Sweden shows that testing for the presence of SARS-CoV-2 nucleic acid can help in containing the virus spread. Detecting the presence of high amounts of SARS-CoV-2 nucleic acid predicts future symptomatic disease, they found.

17 Dec 2020

No added risks to radiation therapy for cancer patients with COVID-19, says study

A team of radiation oncologists at the Zucker School of Medicine at Hofstra/Northwell in the United States aimed to determine if COVID-19 infected cancer patients receiving radiation therapy (RT) have any different outcome than non-infected patients.

17 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Researchers identify key gene necessary for cells to consume and destroy viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system's ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.

17 Dec 2020

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis.

17 Dec 2020

Specific genetic target could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

People with ADHD tendencies are more sensitive to insomnia, severe functional impairments

Individuals with high ADHD-traits that do not meet the criteria for a diagnosis are less able to perform tasks involving attentional regulation or emotional control after a sleepless night than individuals with low ADHD-traits, a new study from Karolinska Institutet published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports.

17 Dec 2020

Novel method reveals the synaptic basis for feature selectivity

A common analogy used to describe the brain is that it consists of tiny interconnected computers.

17 Dec 2020

Medical Science News

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

MFCR awards new grants to support an emerging approach to cancer therapeutics

A protein may be responsible for triggering lung scarring in scleroderma patients

Fish oil supplements not associated with increases in bad cholesterol

Study highlights how the sex differences in COVID-19 are linked to ACE2 protein

PVP at Boston Children's awarded $1 million to extend research into adjuvant-based vaccines

Researchers highlight the need to renew understanding of adverse events in interventional radiology

Errant DNA triggers immune system response against cancer

WEHI researchers suggest potential new approach to treat stomach cancer

How does the UK’s COVID-19 response compare to others in Europe?

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

No added risks to radiation therapy for cancer patients with COVID-19, says study

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers identify key gene necessary for cells to consume and destroy viruses

FAT1 mutations act as tumor suppressor and prevent cancer development, indicates study

Specific genetic target could help explain the variation in COVID-19 effects

Study shows how melanomas assist T cells from identifying and killing tumor cells

People with ADHD tendencies are more sensitive to insomnia, severe functional impairments

Novel method reveals the synaptic basis for feature selectivity

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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