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New computer model can screen drugs for unintended cardiac side effects

UC Davis Health researchers have developed a computer model to screen drugs for unintended cardiac side effects, especially arrhythmia risk.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Vaccine skeptics may process information differently than people

In 2000, the measles virus was declared eliminated from the United States. Despite cases coming in from outside the country, there were few outbreaks because most people were vaccinated against measles. And then 2019 happened.

12 Apr 2020

Hair surface engineering using functional nano containers

"Hair surface engineering: modification of fibrous materials of biological origin using functional ceramic nano containers", a project headed by Rawil Fakhrullin, is supported by the Russian Science Foundation.

12 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020

Recipients of 2020 Sleep Research Society awards announced

The Sleep Research Society has selected three outstanding sleep and circadian scientists as recipients of the 2020 Sleep Research Society awards, which recognize excellence in sleep and circadian research.

12 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

Free program to reduce and replace animal tests in scientific research

From June 22 to 25, students and early-career scientists will gather virtually for a free program of lectures, laboratory tours, interactive sessions, e-poster presentations, and virtual engagement with speakers and attendees on innovative methods to reduce and replace animal tests in toxicology and biomedical science.

11 Apr 2020

World-famous psychological experiment dismissed as not fit-for-purpose

A world-famous psychological experiment used to help explain the brain's understanding of the body, as well as scores of clinical disorders, has been dismissed as not fit-for-purpose in a new academic paper from the University of Sussex.

11 Apr 2020

Study demonstrates the benefits of genomic risk assessment in preventing common diseases

A new Finnish study demonstrated the benefits of large-scale genomic information in estimating the risk of onset for cardiac diseases, diabetes and common cancers.

10 Apr 2020

Tiny sensors reveal how oxygen transfer is altered in diseased lung tissue

A multidisciplinary team of researchers at the University of Illinois at Urbana-Champaign has developed tiny sensors that measure oxygen transport in bovine lung tissue.

10 Apr 2020

Researchers pinpoint genetic variation responsible for development of IBD

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

9 Apr 2020

Novel technology reveals ear's inner secrets

What does it actually look like deep inside our ears? This has been very difficult to study as the inner ear is protected by the hardest bone in the body.

9 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas.

9 Apr 2020

Discovery of key protein may lead to more effective treatments for depression

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes.

9 Apr 2020

Improper cellular cleanup during neurodevelopment may cause lifelong behavioral issues

Improper removal of faulty brain cells during neurodevelopment may cause lifelong behavioral issues, new research from the University of Virginia School of Medicine suggests.

9 Apr 2020

Structural protein may be new target for diagnosis, treatment of depression

Scientists have zeroed in on a structural protein as a new target for the diagnosis and treatment of depression, according to research recently published in JNeurosci.

9 Apr 2020

'Off-the-shelf' artificial cardiac patch improves heart attack recovery in rat and pig models

Researchers from North Carolina State University have developed an "off-the-shelf" artificial cardiac patch that can deliver cardiac cell-derived healing factors directly to the site of heart attack injury. In a rat model of heart attack, the freezable, cell-free patch improved recovery.

8 Apr 2020

Benefits of marijuana for pain relief are not clear-cut, study suggests

Medical marijuana users who say they have high levels of pain are more likely than those with low pain to say they use cannabis three or more times a day, a new study finds.

8 Apr 2020