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Artificial intelligence, probabilistic modeling can improve prediction of survival in cancer patients

Improving the prediction of survival indicators in patients with breast cancer using tools from artificial intelligence and probabilistic modeling is the aim of ModGraProDep, an innovative system presented in a study led by Ramon Clèries, lecturer at the Department of Clinical Sciences of the Faculty of Medicine and Health Sciences of the University of Barcelona and member of the Oncology Master Plan/ICO-IDIBELL.

11 Jun 2020

Protein design can solve the puzzle of Parkinson's disease

Dopamine is a neurotransmitter involved in everything from higher cognitive functions to motor control, motivation, arousal, reinforcement, and sexual gratification, the receptors it acts on have been a longstanding target for treating disorders like Parkinson's disease, which is caused by the degeneration of dopamine-using neurons that control movement.

11 Jun 2020

Transforming spleen to liver could bring new hope for patients suffering from organ shortage

Scientists from Nanjing University and University of Macau have transformed the spleen into a functioning liver in living mice, which could bring new hope for patients suffering from organ shortage worldwide.

11 Jun 2020

Researchers identify two brain phenomena that may explain the side-effects of ketamine

Researchers have identified two brain phenomena that may explain some of the side-effects of ketamine.

11 Jun 2020

Researchers investigate the mechanisms underlying Saccadic Suppression of Displacement

We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina - making our visual system work hard to maintain a stable perceptual world.

11 Jun 2020

Camelina sativa oil and fatty fish have major beneficial effect on lipid metabolism

Camelina sativa oil and fatty fish are rich in polyunsaturated omega-3 fatty acids, but their health benefits seem to differ.

11 Jun 2020

Overactive enzyme causes an inherited form of high blood pressure

A Turkish family from a village near the Black Sea first caught the attention of medical researchers in the early 1970s.

11 Jun 2020

Turning autoimmunity drugs into anti-cancer treatments

Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.

11 Jun 2020

Engineers create new system for high-density EEG imaging of the brain's elusive networks

Understanding the source and network of signals as the brain functions is a central goal of brain research. Now, Carnegie Mellon engineers have created a system for high-density EEG imaging of the origin and path of normal and abnormal brain signals.

11 Jun 2020

Novel fungal compound can turn on p53 gene in cancer cells

Cancers cells use a special technique to propagate; they delete their "programmed death" gene through mutation, "forget" to die when their lifetime is over, and continue to grow instead.

11 Jun 2020

New methods to study the impacts of puberty suppression in brains of transgender youth

A new set of expert consensus-based recommendations lays out how best to study possible neurodevelopmental impacts of pubertal suppression treatment in transgender youth.

11 Jun 2020

A lead compound can significantly reduce or eliminate toxoplasmosis and malaria

Toxoplasma gondii infection is one of the most frequent parasitic infections of humans. This parasite is present in the brain of an estimated two billion people--about 40 percent of all humans on earth. It is endemic throughout the world, causing water and food-borne epidemics that result in toxoplasmosis.

10 Jun 2020

Oncotarget: mi R-151a overexpression enhances tumor-associated angiogenesis

Volume 11, Issue 23 of @Oncotarget reported that the authors have previously established that mi R-151a functions as an onco-mi R in non-small cell lung cancer cells by inducing partial EMT and enhancing tumor growth.

10 Jun 2020

Baboon could prove to be a relevant model to test Alzheimer's disease interventions

Scientists at Texas Biomedical Research Institute's Southwest National Primate Research Center recently published findings indicating the baboon could prove to be a relevant model to test therapeutics and interventions for neurodegenerative diseases, such as early stage Alzheimer's and related dementias.

10 Jun 2020

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Volume 11, Issue 22 of @Oncotarget reported that there are rationale and evidence supporting immune therapy in Ovarian Cancers.

10 Jun 2020

Hyperprogression to immune blockade followed by a response with cabozantinib in metastatic RCC

Volume 11, Issue 22 of @Oncotarget reported that more and more patients receive first-line treatment with immunotherapy combinations and not all patients respond in metastatic renal cell carcinoma.

10 Jun 2020

Researchers evaluate survivin expression in neuroendocrine tumors

Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes.

10 Jun 2020

Study assesses the acute impact of cannabis among real-world users

Smoking high-potency marijuana concentrates boosts blood levels of THC more than twice as much as smoking conventional weed, but it doesn't necessarily get you higher, according to a new study of regular users published today by University of Colorado Boulder researchers.

10 Jun 2020

The 2019 3Rs prize awarded to two pieces of novel research

The 2019 3Rs prize has been jointly awarded to Dr Francesca Nunn and Dr Marta Shahbazi for papers describing research that reduces the number of chickens and mice respectively. The 3Rs prize is awarded by the NC3Rs and sponsored by GSK.

10 Jun 2020

COVID-19 mouse model could accelerate the search for treatments, vaccines

The global effort to quickly develop drugs and vaccines for COVID-19 has been hampered by limited numbers of laboratory mice that are susceptible to infection with SARS-CoV-2, the virus that causes COVID-19.

10 Jun 2020

Medical Science News

Artificial intelligence, probabilistic modeling can improve prediction of survival in cancer patients

Protein design can solve the puzzle of Parkinson's disease

Transforming spleen to liver could bring new hope for patients suffering from organ shortage

Researchers identify two brain phenomena that may explain the side-effects of ketamine

Researchers investigate the mechanisms underlying Saccadic Suppression of Displacement

Camelina sativa oil and fatty fish have major beneficial effect on lipid metabolism

Overactive enzyme causes an inherited form of high blood pressure

Turning autoimmunity drugs into anti-cancer treatments

Engineers create new system for high-density EEG imaging of the brain's elusive networks

Novel fungal compound can turn on p53 gene in cancer cells

New methods to study the impacts of puberty suppression in brains of transgender youth

A lead compound can significantly reduce or eliminate toxoplasmosis and malaria

Oncotarget: mi R-151a overexpression enhances tumor-associated angiogenesis

Baboon could prove to be a relevant model to test Alzheimer's disease interventions

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Hyperprogression to immune blockade followed by a response with cabozantinib in metastatic RCC

Researchers evaluate survivin expression in neuroendocrine tumors

Study assesses the acute impact of cannabis among real-world users

The 2019 3Rs prize awarded to two pieces of novel research

COVID-19 mouse model could accelerate the search for treatments, vaccines

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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