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New initiative identifies key parameters underlying effective anti-tumor immunity

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

9 Oct 2020

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

A new Center for Precision Animal Modeling, or C-PAM, has been created at the University of Alabama at Birmingham, supported by a five-year, $9.3 million grant from the National Institutes of Health's Office of Research Infrastructure Programs.

9 Oct 2020

Too little sugar is the cause of perforated bones

Bone marrow cancer is currently an incurable disease that affects about 400 people in Norway every year. Professor Therese Standal at NTNU has now found an important reason for bone destruction in people with this disease.

9 Oct 2020

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

9 Oct 2020

Study compares the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Virologists at the Rega Institute have shown that the anti-malaria drug hydroxychloroquine does not limit SARS-CoV-2 coronavirus replication in hamsters.

9 Oct 2020

Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

In June, two studies in Science reported an antibody cocktail against SARS-CoV-2 developed from studies in humanized mice and recovering patients. The two antibody cocktail was designed to bind the virus to reduce the risk of a drug-resistant form emerging.

9 Oct 2020

Serum antibodies from SARS-CoV patients effectively neutralized SARS-CoV-2 in cultured cells

Antibodies in serum samples collected from patients infected with SARS-CoV during the 2003 outbreak effectively neutralized SARS-CoV-2 infection in cultured cells, according to a new study.

9 Oct 2020

Exuberant activation of immune cells in severe COVID-19 resembles lupus

In severe cases of COVID-19, Emory researchers have been observing an exuberant activation of immune cells, resembling acute flares of systemic lupus erythematosus (SLE), an autoimmune disease.

9 Oct 2020

Over $1 million CIHR funding for six uOttawa COVID-19 mental health projects

Six University of Ottawa-affiliated projects focusing on COVID-19's impact on mental health have won important funding grants totaling over $1 million from the Canadian Institutes of Health Research (CIHR).

9 Oct 2020

Research shows choroid plexus can act as a conduit for prenatal inflammation

Floating in fluid deep in the brain are small, little understood fronds of tissue. Two new studies reveal that these miniature organs are a hotbed of immune system activity.

9 Oct 2020

miR-29 is an age-dependent regulator of developmental plasticity in the visual cortex

Postnatal development of the brain after birth is characterized by temporary, function-specific windows of high plasticity (critical or sensitive periods).

9 Oct 2020

Hypoxic exosomes promote stemness in EWS sarcoma, indicates study

The cover for issue 40 of Oncotarget features Figure 5, "miR-210 silences the proapoptosis member CASP8AP2," by Kling, et al. which reported that hypoxic Ewing's sarcoma cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS cells by enhancing survival.

9 Oct 2020

Researchers provide unique experiment for creating artificial tissue-engineered vascular graft

Researchers from St. Petersburg provided a unique experiment. They implanted a polymer scaffold as a vascular prosthesis into the rat abdominal aorta and monitored the process of its bioresobtion for 16 months. An artificial vessel was formed where the scaffold was located.

9 Oct 2020

Researchers develop hand-held device to measure cancer biomarker

Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.

9 Oct 2020

New quality control system in protein production assembly can shed light on neurogenerative disease

Recent work led by Carnegie's Kamena Kostova revealed a new quality control system in the protein production assembly line with possible implications for understanding neurogenerative disease.

9 Oct 2020

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

Heidelberg neurobiologists decode central mechanism of degenerative processes in the brains of mouse models and develop new principle for therapeutic agents

9 Oct 2020

Transplantation of pig hearts may solve chronic shortage of donor organs

The goal of harvesting hearts from pigs to solve the chronic shortage of these donor organs appears to be in reach, according to a new scientific review by researchers at Massachusetts General Hospital (MGH).

9 Oct 2020

New model can simulate and analyze large number of viral infections

It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans.

9 Oct 2020

Scientists recreate initial steps of HIV infection in a test tube

Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome).

9 Oct 2020

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases - including cancer -, an area of research where progress is constantly being made.

9 Oct 2020

Medical Science News

New initiative identifies key parameters underlying effective anti-tumor immunity

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

Too little sugar is the cause of perforated bones

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

Study compares the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

Serum antibodies from SARS-CoV patients effectively neutralized SARS-CoV-2 in cultured cells

Exuberant activation of immune cells in severe COVID-19 resembles lupus

Over $1 million CIHR funding for six uOttawa COVID-19 mental health projects

Research shows choroid plexus can act as a conduit for prenatal inflammation

miR-29 is an age-dependent regulator of developmental plasticity in the visual cortex

Hypoxic exosomes promote stemness in EWS sarcoma, indicates study

Researchers provide unique experiment for creating artificial tissue-engineered vascular graft

Researchers develop hand-held device to measure cancer biomarker

New quality control system in protein production assembly can shed light on neurogenerative disease

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

Transplantation of pig hearts may solve chronic shortage of donor organs

New model can simulate and analyze large number of viral infections

Scientists recreate initial steps of HIV infection in a test tube

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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