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Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

Study reveals novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these therapies.

26 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

Researchers from the University of Michigan found significant pupillary changes in high-school football athletes after they had sustained a high-acceleration head impact.

26 Nov 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Study examines how our brain fuses with musical rhythm

When listening to a song or watching a dance, humans tend to follow the rhythm of the music. This is because one fundamental aspect of music is its rhythm, the way we synchronize with the temporal regularities of a melody or a dance. A recent study explores how our brain fuses with musical rhythm and the extent to which humans share this ability with other animals.

26 Nov 2019

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who looked at those gene editors writes in the 26 November issue of Cell Reports.

26 Nov 2019

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments.

26 Nov 2019

Targeting molecular mechanisms could be beneficial in diabetic wound care

When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down wound healing.

26 Nov 2019

New way to thwart HIV infection at early stages

1.7 million. That's how many people are infected with the human immunodeficiency virus (HIV) each year worldwide. 1.7 million people who are condemned to lifelong antiretroviral therapy (ART) or risk developing fatal AIDS . Out of the 37.9 million people living with HIV (PLWH), 22.3 million have access to ART, allowing them to have an almost normal lifespan.

26 Nov 2019

Sheffield research receives £800k to develop new gene therapy to treat CVD

Cardiac research in Sheffield has received a major boost from the British Heart Foundation in the form of an £800,000 award to develop a new gene therapy to treat cardiovascular disease (CVD).

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Medical Science News

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Study reveals novel pathway to target colorectal cancer

Space travel can affect intestinal function of astronauts

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Study examines how our brain fuses with musical rhythm

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Targeting molecular mechanisms could be beneficial in diabetic wound care

New way to thwart HIV infection at early stages

Sheffield research receives £800k to develop new gene therapy to treat CVD

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

New method for correcting hypoxic conditions of the central nervous system

Researchers find new way to protect against disease in MS model

Studying the genomes of hibernating mammals could improve understanding and treatment of obesity

Study demonstrates potential therapeutic use of ketamine for alcohol addiction

Fertility treatments cause epigenetic changes in mouse embryos, study finds

New method to separate two variants of common herpes virus linked to multiple sclerosis

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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