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Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Doctors bring dead donor heart back to life in US first

A team has become the first in the US to reanimate the heart of a deceased donor and transplant it into a recipient.

3 Dec 2019

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel and exploitable target in overcoming this treatment obstacle.

3 Dec 2019

Researchers identify new drug target for treating neurological disorders

Understanding how the brain processes sweet, bitter and umami tastes may one day help researchers design more effective drugs for neurological disorders.

3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

New computational method can help predict and design allosteric functions in proteins

Called the "second secret of life", allostery is one of the most fundamental processes of biology and has been a central focus among scientists across the life sciences spectrum, from fundamental biology to drug development.

3 Dec 2019

Discovery could offer insight into different risk of diseases in African Americans

The percentage of African ancestry in a person's genome determines the level that certain genes are expressed, called mRNA, according to a new Northwestern Medicine study.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

New findings regarding maintenance and functioning of the endosome

On a daily basis, multitudes of molecules enter each cell in our body. These can be nutrients or signal molecules or pathogenic microorganisms. An organelle in the cell directs these molecules to other stations for further processing.

3 Dec 2019

Researchers identify key protein required for therapeutic resistance in aggressive breast cancer

Researchers at the Lady Davis Institute have identified a key protein that is required for resistance to chemotherapy in the most aggressive form of breast cancer. This holds the promise of opening the door to new therapies for overcoming drug resistance.

2 Dec 2019

Blood proteins could help provide a comprehensive 'liquid health check' in future

Proteins in our blood could in future help provide a comprehensive 'liquid health check', assessing our health and predicting the likelihood that we will we will develop a range of diseases, according to research published today in Nature Medicine.

2 Dec 2019

Study reveals clue to preventing addiction relapse

With any addiction in which a user has successfully resisted a chemical, activity or substance, relapse is vexing. And with opioids, it's often deadly. Fatal overdoses following relapse from an opioid addiction is reaching epidemic proportions.

2 Dec 2019

Common clinical indicators of immune status and inflammation can predict mortality

A new collaborative study led by Cleveland Clinic and University Hospitals has found that commonly used clinical indicators of immune status and inflammation can predict mortality in the general population.

2 Dec 2019

Research uncovers mechanism that triggers inflammatory process by Mayaro virus

The mechanism by which defense cells respond to infection by Mayaro virus has been described by a team affiliated with the Center for Research on Inflammatory Diseases - CRID in an article published in the journal PLOS Pathogens.

2 Dec 2019

Researchers identify brain networks that play key role in suicide risk

An international team of researchers has identified key networks within the brain they say interact to increase the risk that an individual will think about - or attempt - suicide.

2 Dec 2019

SDSU researchers show cancer-inhibiting potential of flavonoid metabolite

Eating fruits and vegetables is more important than ever.

2 Dec 2019

New treatment could make passing kidney stones faster and less painful

Every year, more than half a million Americans visit the emergency room for kidney stone problems. In most cases, the stones eventually pass out of the body on their own, but the process can be excruciatingly painful.

2 Dec 2019

Researchers unravel how the brain processes visual information

A team of scientists led by Karl Farrow at NeuroElectronics Research Flanders (NERF, empowered by imec, KU Leuven and VIB) is unraveling how our brain processes visual information.

2 Dec 2019

Research lays foundation for patient-specific 3D-printed meniscus

The human knee joint is the largest and complex joint in the body compared to other joints. It has various hard and soft tissue elements to provide stability and proper functioning including the meniscus.

2 Dec 2019

Brain receptor that regulates body temperature may also be the key to rapid weight loss

The brain mechanism that enables us to maintain a constant body temperature may also be the key to rapid weight loss, a new study finds.

2 Dec 2019

Medical Science News

Inhibition of a protease could improve the treatment of IBD, study shows

Doctors bring dead donor heart back to life in US first

Study: Calcium signaling can help address drug resistance to non-Hodgkin lymphoma

Researchers identify new drug target for treating neurological disorders

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

New computational method can help predict and design allosteric functions in proteins

Discovery could offer insight into different risk of diseases in African Americans

Key component of immune response is activated by short RNAs, shows study

New findings regarding maintenance and functioning of the endosome

Researchers identify key protein required for therapeutic resistance in aggressive breast cancer

Blood proteins could help provide a comprehensive 'liquid health check' in future

Study reveals clue to preventing addiction relapse

Common clinical indicators of immune status and inflammation can predict mortality

Research uncovers mechanism that triggers inflammatory process by Mayaro virus

Researchers identify brain networks that play key role in suicide risk

SDSU researchers show cancer-inhibiting potential of flavonoid metabolite

New treatment could make passing kidney stones faster and less painful

Researchers unravel how the brain processes visual information

Research lays foundation for patient-specific 3D-printed meniscus

Brain receptor that regulates body temperature may also be the key to rapid weight loss

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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