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Inhibiting mutant CHIP protein activity could decrease severity of ataxia disease symptoms

For the first time, the UNC School of Medicine lab of Jonathan Schisler, MS, PhD, linked the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare disorders.

6 Nov 2019

Nanotechnologies can lead to big advances in cancer therapy

Nami Therapeutics Corporation, which gets its name from the Mandarin word for "nano," is committed to using nanotechnologies to make big advances in cancer therapy.

6 Nov 2019

CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in human, which require high precision.

6 Nov 2019

Researchers reveal mechanisms that lead to onset of Type 1 diabetes

Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to the onset of Type 1 Diabetes (T1D).

6 Nov 2019

Novel mouse model can help monitor kidney disease progression and perform drug screening

Chronic kidney disease affects 750 million people each year. Aging populations and an increase in diseases such as diabetes will lead to a greater burden of kidney disease.

6 Nov 2019

Gene-editing technique CRISPR trialed for first time as cancer treatment

The go-ahead has been given for the first trials using CRISPR as an alternative therapy for treating cancer.

6 Nov 2019

Review: Clitoris is important for reproduction

A recent review published in Clinical Anatomy highlights evidence that the female clitoris is important for reproduction.

6 Nov 2019

New therapy has potential to repair cells damaged by noise, prevent hearing loss

More than 700 million people worldwide suffer from some degree of hearing loss, including an estimated 20 percent of Americans over the age of 12, according to medical experts.

6 Nov 2019

Study shows how myelinated mammalian nerves propagate nerve impulses at high frequencies

University of Alabama at Birmingham researchers, for the first time ever, have achieved patch-clamp studies of an elusive part of mammalian myelinated nerves called the Nodes of Ranvier.

6 Nov 2019

New model based on dynamic neural code can help humans to localize sounds

One of the enduring puzzles of hearing loss is the decline in a person's ability to determine where a sound originates, a key survival faculty that allows animals - from lizards to humans - to pinpoint the location of danger, prey and group members.

6 Nov 2019

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments.

6 Nov 2019

Study shows how the complex neural map of human brain operates

Fans of the blockbuster movie "Iron Man 3" might remember the characters step inside the digital projection of a "big brain" and watch as groups of neurons are "lit up" along the brain's neural "map" in response to physical touch.

6 Nov 2019

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

6 Nov 2019

Chiral interactions could be leveraged to improve the performance of drug-delivery nanoparticles

MIT engineers have shown that they can enhance the performance of drug-delivery nanoparticles by controlling a trait of chemical structures known as chirality -- the "handedness" of the structure.

6 Nov 2019

Study: Spherical exosomes could help in treating acute kidney injury

Like a swarm of construction workers in the aftermath of a destructive storm, cargo-filled, nanometer-sized spheres arrive on the scene following an acute kidney injury.

5 Nov 2019

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

With CAR T cell therapy, a patient's own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and that they are continuing to fight disease weeks, months, or even years later?

5 Nov 2019

Neural networks predict which images optimally excite particular neurons

A new study published in Neuroscience reveals how computation can be used to find out the visual stimulation to which the brain cells respond most frequently and productively.

5 Nov 2019

Researchers identify potential drug targets for glioblastoma

Researchers at Karolinska Institutet in Sweden have identified 10 tumor-specific potential drug targets for the brain tumor glioblastoma. The results are presented in the scientific journal Cell Reports.

5 Nov 2019

Physics of windshield-cracking raindrops may help doctors shatter kidney stones

A plane has to be going pretty fast for a mere raindrop to crack its windshield, but it can happen. Now, new models of the physics behind the improbable feat may just help doctors crack kidney stones to pieces.

5 Nov 2019

Household chores in childhood not linked to self-control development

Although assigning household chores is considered an essential component of child-rearing, it turns out they might not help improve children's self-control, a coveted personality trait that allows people to suppress inappropriate impulses, focus their attention and perform an action when there is strong tendency to avoid it.

5 Nov 2019

Medical Science News

Inhibiting mutant CHIP protein activity could decrease severity of ataxia disease symptoms

Nanotechnologies can lead to big advances in cancer therapy

CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

Researchers reveal mechanisms that lead to onset of Type 1 diabetes

Novel mouse model can help monitor kidney disease progression and perform drug screening

Gene-editing technique CRISPR trialed for first time as cancer treatment

Review: Clitoris is important for reproduction

New therapy has potential to repair cells damaged by noise, prevent hearing loss

Study shows how myelinated mammalian nerves propagate nerve impulses at high frequencies

New model based on dynamic neural code can help humans to localize sounds

Study reveals key mechanism that helps cells to adapt to low-nutrient conditions

Study shows how the complex neural map of human brain operates

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Chiral interactions could be leveraged to improve the performance of drug-delivery nanoparticles

Study: Spherical exosomes could help in treating acute kidney injury

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

Neural networks predict which images optimally excite particular neurons

Researchers identify potential drug targets for glioblastoma

Physics of windshield-cracking raindrops may help doctors shatter kidney stones

Household chores in childhood not linked to self-control development

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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