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Scientists discover small molecule that may slow or stop Parkinson's progression

A collaboration between scientists at Rutgers University and The Scripps Research Institute led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

23 Jan 2020

Landmark study identifies 102 genes associated with autism risk

In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated with intellectual disability and developmental delay, conditions which often overlap.

23 Jan 2020

Scientists use human stem cells to make pain-killing neurons

Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

23 Jan 2020

Researchers identify novel cellular entry factor for AAV vector types

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.

23 Jan 2020

Novel drug can simultaneously help diagnose, treat gastric cancer

A novel drug, named "FerriIridium", can simultaneously help diagnose and treat gastric cancer. The initially weakly active precursor (prodrug), based on an iridium-containing compound, is selectively activated only after reaching the interior of a tumor cell. This is possible because of the higher amount of iron present there, report scientists in the journal Angewandte Chemie.

23 Jan 2020

Researchers solve long-standing mystery linked to contraction of heart cells

We've all felt the effects of an adrenaline rush. Faced with danger, real or perceived, the heart beats faster, breathing quickens and muscles tighten as the body prepares to fight a threat or flee from it.

23 Jan 2020

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Promoting the signaling pathway of reelin -an essential extracellular protein for the neuronal migration and synaptic plasticity- could be an effective therapeutical strategy to counterbalance the main cognitive, biochemical and behavioral alterations seen in Alzheimer's and other pathologies associated with Tau protein, as shown in a new study with animal models -published in the journal Progress in Neurobiology.

23 Jan 2020

Combination of two immune defense strategies could afford alternative approach to treating sepsis

The human immune system uses two pre-programmed strategies to tackle infection. One is fever, a resistance mechanism that tries to eliminate a pathogen by raising the body's temperature.

23 Jan 2020

Researchers analyze how the brain processes rewards

Researchers from HSE University, Skoltech and the University of Toronto analyzed data from 190 fMRI studies and found out that food, sex and money implicate similar brain regions whereas different types of reward favor the left and right hemispheres differently.

23 Jan 2020

Scientists discover new drug target for prostate cancer in the non-coding genome

Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.

23 Jan 2020

Research reveals damaging impact of visible and infrared light on the skin

The damage visible and infrared light can do to our skin has been revealed for the first time in new research by scientists at Newcastle University, UK.

23 Jan 2020

Study casts doubt on the reliability of donated kidney assessment for transplant

A study led by researchers at Columbia University Irving Medical Center have made an important discovery about the way donated kidneys are assessed before transplantation, that could call into question current decision-making processes about whether an organ can be used or not.

23 Jan 2020

Hot flashes associated with decreased verbal memory

If you're having difficulty identifying the right word to express yourself clearly or remembering a story correctly, you may blame menopause.

23 Jan 2020

Protein p38 plays key role in supporting lung cancer growth

In 2018, 1.7 million people died from lung cancer worldwide, a number equivalent to the population of Barcelona. The high mortality rate of lung cancer reflects the need for the development of treatments that are more efficient.

23 Jan 2020

Adolescents with PCOS and obesity have more 'unhealthy' gut bacteria

Teens with obesity and polycystic ovary syndrome have more "unhealthy" gut bacteria suggesting the microbiome may play a role in the disorder, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

23 Jan 2020

Arginine depletion could form the basis for potential rheumatoid arthritis therapies

A group from the MedUni Vienna has identified a role for the endogenous amino acid arginine in the growth of osteoclasts in rheumatoid arthritis.

23 Jan 2020

Protein linked with neurodegenerative diseases may help explore the aggressive behavior of gliomas

A protein typically associated with neurodegenerative diseases like Alzheimer's might help scientists explore how gliomas, a type of cancerous brain tumor, become so aggressive.

22 Jan 2020

Controlled-release opioids may lead to endocarditis in injection drug users

A new study from ICES, Lawson Health Research Institute and Western University suggests that injection drug users prescribed controlled-release hydromorphone are three times more likely to develop endocarditis, a serious bacterial heart infection, when compared to those prescribed other opioids.

22 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Researchers confirm safety of cancer-specific PET probe in first-in-human clinical studies

A group of researchers led by Assistant Professor WATABE Tadashi of the Graduate School of Medicine of Osaka University achieved the stable domestic production of automatic synthesis modules for positron emission tomography (PET) probe F-18 NKO-035, a LAT1-selective amino acid derivative radiolabeled with 18F, confirming its safety in first-in-human clinical studies conducted at Osaka University Hospital in November 2019.

22 Jan 2020

Medical Science News

Scientists discover small molecule that may slow or stop Parkinson's progression

Landmark study identifies 102 genes associated with autism risk

Scientists use human stem cells to make pain-killing neurons

Researchers identify novel cellular entry factor for AAV vector types

Novel drug can simultaneously help diagnose, treat gastric cancer

Researchers solve long-standing mystery linked to contraction of heart cells

Reelin can reverse the main pathological processes associated with Alzheimer's, other tauopathies

Combination of two immune defense strategies could afford alternative approach to treating sepsis

Researchers analyze how the brain processes rewards

Scientists discover new drug target for prostate cancer in the non-coding genome

Research reveals damaging impact of visible and infrared light on the skin

Study casts doubt on the reliability of donated kidney assessment for transplant

Hot flashes associated with decreased verbal memory

Protein p38 plays key role in supporting lung cancer growth

Adolescents with PCOS and obesity have more 'unhealthy' gut bacteria

Arginine depletion could form the basis for potential rheumatoid arthritis therapies

Protein linked with neurodegenerative diseases may help explore the aggressive behavior of gliomas

Controlled-release opioids may lead to endocarditis in injection drug users

Scientists reverse HIV latency, take major scientific step toward curative therapies

Researchers confirm safety of cancer-specific PET probe in first-in-human clinical studies

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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