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Researchers develop novel mathematical framework for mapping out drug interaction

Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs influence each other. Thus, elucidating how two given drugs interact, and whether they have a beneficial effect, would mean a major step towards drug development to treat diseases more effectively in the future.

13 Nov 2019

Fertilization discovery reveals egg's role, potentially paves way for new contraceptive

An unexpected discovery about fertilization from the University of Virginia School of Medicine reveals new insights on how sperm and egg fuse and could have major implications for couples battling infertility – and may lead to a future male contraceptive.

13 Nov 2019

Scientists explore expansion of cytotoxic CD4 T-cells in supercentenarians

Scientists from the RIKEN Center for Integrative Medical Science (IMS) and Keio University School of Medicine in Japan have used single-cell RNA analysis to find that supercentenarians--meaning people over the age of 110--have an excess of a type of immune cell called cytotoxic CD4 T-cells.

13 Nov 2019

'Smart toilets' may work as real-time method of monitoring health

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity - the humble toilet - may have potential to outperform them all.

13 Nov 2019

Researchers take major step towards developing a viable vaccine for malaria

Researchers have narrowed down the malaria proteins and disease-fighting antibodies that could be used to develop a vaccine against the most severe forms of malaria.

13 Nov 2019

Johns Hopkins launches new center for 'immunoengineering' research

If the saying that two heads are better than one is true, then joining two fields of science may be better than one to spur more advances in medicine.

13 Nov 2019

Researchers use phage therapy to successfully treat alcoholic liver disease

Researchers have successfully used bacteriophage (phage) therapy to eliminate alcohol-related liver disease in an animal model.

13 Nov 2019

Campaigns promoting sun-protective behaviors seem to be working in the US

Public health programs designed to promote sun-protective behaviors seem to be gaining traction in the United States.

13 Nov 2019

Bacteriophages could treat E. coli without damaging the gut, new study says

Researchers in the US have developed a new therapy that uses a unique bacteriophage to treat E. coli infections.

13 Nov 2019

Ketamine may be viable treatment option for male alcohol use disorder patients

The drug ketamine decreases alcohol consumption in male, but not female, rats, according to new research published in eNeuro. The findings suggest that ketamine may be a viable treatment option for male patients with an alcohol use disorder.

13 Nov 2019

Scientists move closer towards developing an effective malaria vaccine

Scientists have taken another big step forward towards developing a vaccine that’s effective against the most severe forms of malaria.

13 Nov 2019

Kratom may be effective, but not entirely safe to treat alcohol use disorder

Lawmakers across the United States continue to debate the safety of kratom, an opioid-containing plant that has been listed as a "drug of concern" by the U.S. Food and Drug Administration. Kratom is sold over the counter in specialty stores and online.

13 Nov 2019

Scientists find driver for more deadly prostate cancer

A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say.

13 Nov 2019

Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

Certain brain regions must be intact in stroke survivors with aphasia for successful speech entrainment

In an article in Brain, researchers at the Medical University of South Carolina (MUSC) and elsewhere report which brain regions must be intact in stroke survivors with aphasia if they are to perform well in a speech entrainment session, successfully following along with another speaker.

12 Nov 2019

UAB study suggests potential treatment target for IPF

Long-held dogma says lung fibrosis in diseases like idiopathic pulmonary fibrosis, or IPF, results from recurrent injury to alveolar epithelium that is followed by dysregulated repair.

12 Nov 2019

Anthrax may soon help more people fight against bladder cancer

Anthrax may soon help more people win the fight against bladder cancer, which the Centers for Disease Control and Prevention says strikes about 72,000 Americans each year and kills about 16,000, and is one of the most expensive cancers to treat.

12 Nov 2019

Listening to instrumental music may relieve cardiac stress

Stress while driving is a risk factor for the development of cardiovascular disease and sudden cardiac complications such as heart attack (myocardial infarction), according to studies published in recent years. Selecting suitable driving music may be one way to mitigate this risk.

12 Nov 2019

White noise background improves hearing, study shows

Noise is not the same as noise - and even a quiet environment does not have the same effect as white noise.

12 Nov 2019

Systematic review: Evidence about effectiveness of blue light therapy for acne is lacking

Conclusions about the effectiveness of blue light therapy for acne are limited. A new systematic review and meta-analysis of 14 randomized controlled trials of blue light therapy for acne shows methodological and reporting limitations--including small sample sizes, short intervention periods, and variation in reporting quality for acne outcomes.

12 Nov 2019