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Relevant social stimulus may diminish the preference to drugs

Researchers of the Faculty of Psychology of the University of Malaga (UMA), specialized in addictive disorders, have demonstrated in an animal model that the presence of a relevant social stimulus reduces interest in cocaine.

15 Nov 2019

Modern resuscitation science: Illuminating the complex processes of death

On Monday, November 18, 2019 the New York Academy of Sciences and the Critical Care and Resuscitation Research Program at NYU Langone will present a two part event titled What Happens When We Die? at the Academy's offices in downtown Manhattan.

15 Nov 2019

Newly identified antibody has potential to stop, reverse pulmonary arterial hypertension

Scientists at the University of Sheffield, working in collaboration with drug and vaccine developer Kymab Ltd, Cambridge, have identified a novel antibody that has the potential to become a new treatment for pulmonary arterial hypertension (PAH).

15 Nov 2019

New way to promote insulin production in pre-diabetes phase discovered

Nanyang Technological University, Singapore scientists have discovered that a type of immune cell known as 'pancreatic islet macrophages' is capable of promoting insulin production during the pre-diabetes phase.

15 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury.

15 Nov 2019

Broccoli's effects on kidney health may depend on individual's genetics

New research indicates that the benefits of a dietary compound on kidney health may depend on an individual's genetics. The findings, which appear in an upcoming issue of JASN, may be helpful for tailoring interventions to prevent or treat kidney disease.

15 Nov 2019

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

In a surprising finding using the standard animal model of Down syndrome (DS), scientists were able to correct the learning and memory deficits associated with the condition -- the leading genetic cause of cognitive disability and the most frequently diagnosed chromosomal disorder in the U.S. -- with drugs that target the body's response to cellular stresses.

15 Nov 2019

Gut microbes may alter the aging process, study finds

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) has found that microorganisms living in the gut may alter the aging process, which could lead to the development of food-based treatment to slow it down.

14 Nov 2019

Research shows how bacteria associated with Crohn's disease tolerate antibiotics

Bacteria associated with Crohn's disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14 in the open-access journal PLOS Pathogens by Olivier Espéli of the College de France and PSL Research University in Paris, France, and colleagues.

14 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Research explains why immunotherapy fails against prostate cancer bone metastases

Prostate cancer that spreads to the bone triggers the destruction of bone tissue that, in turn, thwarts the effectiveness of immune checkpoint inhibitors by blocking the development of T cells that are crucial to successful treatment, researchers from The University of Texas MD Anderson Cancer Center report in Cell.

14 Nov 2019

Study sheds light on how Zika virus causes microcephaly in newborns

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons.

14 Nov 2019

Understanding how pressure is regulated in the eye could lead to new treatments for glaucoma

Scientists in the University of Arizona Department of Physiology have identified a potential molecular mechanism that may hold the key to understanding how pressure is regulated in the eye.

14 Nov 2019

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Pain impacts nearly every individual at some point in their lives. With more than 25 million adults in the U.S. experiencing daily pain, the U.S. is facing a crisis due to the high prevalence of chronic pain and associated opioid use disorder and overdose deaths.

14 Nov 2019

Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

The dopamine D2 receptor has a previously unobserved role in modulating Wnt expression and control of cell proliferation, according to a new study from the George Washington University and the University of Pittsburgh.

14 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Integral Molecular receives NIH contract for $5.5 million to advance vaccine discovery

The National Institute of Allergy and Infectious Diseases has awarded Integral Molecular a contract (75N93019C00073) which will provide up to $5.5M over the next five years to define antibody responses to pathogenic viruses including Zika, Marburg and equine encephalitis viruses, aiding the discovery of vaccines and therapeutics against these currently untreatable and often lethal viruses.

14 Nov 2019

Study on sea sponge opens up possibilities to create new antitumor drugs

Chemists from Far Eastern Federal University's School of Natural Sciences developed a new method to synthesize biologically active derivatives of fascaplysin -- cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study.

14 Nov 2019

Medical Science News

Relevant social stimulus may diminish the preference to drugs

Modern resuscitation science: Illuminating the complex processes of death

Newly identified antibody has potential to stop, reverse pulmonary arterial hypertension

New way to promote insulin production in pre-diabetes phase discovered

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Broccoli's effects on kidney health may depend on individual's genetics

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Gut microbes may alter the aging process, study finds

Research shows how bacteria associated with Crohn's disease tolerate antibiotics

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Research explains why immunotherapy fails against prostate cancer bone metastases

Study sheds light on how Zika virus causes microcephaly in newborns

Understanding how pressure is regulated in the eye could lead to new treatments for glaucoma

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

New insights into how immune system and inflammation play a role in PD

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Integral Molecular receives NIH contract for $5.5 million to advance vaccine discovery

Study on sea sponge opens up possibilities to create new antitumor drugs

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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