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Sphingolipids associated with heart disease in African Americans with lupus

When it comes to cholesterol, we've come to accept a simple narrative. Our risk of heart disease is lower when we have more "good cholesterol," or high-density lipoproteins (HDL), and less "bad cholesterol," or low-density lipoproteins (LDL) and triglycerides.

21 Nov 2019

Doctors place patients in suspended animation in first trial of its kind

For the first time, doctors have placed people in suspended animation in an effort to repair fatal

21 Nov 2019

Experimental vaccine elicits antibodies that can neutralize multiple HIV strains

An experimental HIV vaccine developed by scientists at Scripps Research and the nonprofit vaccine research organization IAVI has reached an important milestone by eliciting antibodies that can neutralize a wide variety of HIV strains.

21 Nov 2019

Recently discovered protein may play key role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism.

21 Nov 2019

Exploring the links between chronic stress, inflammation and depression

Chronic stress can inflame our brain, destroy the connections between our neurons and result in depression, scientists say.

21 Nov 2019

Machine learning successfully replicates cell architecture

A new study reports the use of machine learning to help form complex cell architectures from pluripotent stem cells.

21 Nov 2019

Rheumatoid arthritis linked to other diseases, finds new study

A study found that risk of developing rheumatoid arthritis is higher in people with certain diseases.

21 Nov 2019

Air pollution associated with memory decline and Alzheimer's-like brain atrophy

Women in their 70s and 80s who were exposed to higher levels of air pollution experienced greater declines in memory and more Alzheimer's-like brain atrophy than their counterparts who breathed cleaner air, according to USC researchers.

20 Nov 2019

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules -- including one called resolvin D1 -- play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood.

20 Nov 2019

Inflammatory processes drive progression of neurodegenerative brain diseases

Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons.

20 Nov 2019

Researchers uncover novel pathogenic mechanism in Huntington’s disease

Researchers from the Institute of Neurosciences of the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute described a mechanism, the increase of proteinaceous synthesis, which takes part in the degeneration of the type of neurons that are affected in Huntington's disease, a genetic neurodegenerative disease.

20 Nov 2019

Impaired gene expression may influence aging via altered cellular metabolism

Throughout history, humans have been obsessed with finding a way to prevent aging and prolong life. Although the mechanisms have long eluded us, modern science is revealing more and more about the aging process. Now, researchers from Japan have uncovered new information about the genetic processes that may trigger age-related disorders, including low energy production and low cellular growth.

20 Nov 2019

Newly developed ChiTaRS database can collect cases of druggable fusion targets

When sections from two separate genes merge due to various factors, such as translocation or splicing, the hybrid that is formed is called a gene fusion. In recent years, it has been discovered that these fusion events play a vital role in the development of cancers and other complex diseases.

20 Nov 2019

JACM special issue focuses on challenges in inter-rater reliability in Traditional Chinese Medicine

Diagnostic agreement between practitioners is an ongoing challenge in the evaluation of Traditional Chinese Medicine and other healthcare systems that rely on constitutional types.

20 Nov 2019

Researchers discover a peptide involved in both migraine and opioid-overuse pain

About 10% of the world population suffers from migraine headaches, according to the National Institute of Neurological Disorders and Stroke.

20 Nov 2019

Researchers examine models for automatic bone age estimation

Ensembles created using models submitted to the RSNA Pediatric Bone Age Machine Learning Challenge convincingly outperformed single-model prediction of bone age, according to a study published in the journal Radiology: Artificial Intelligence.

20 Nov 2019

Movements affect the processing of visual stimuli

How do we perceive our environment? What is the influence of sensory stimuli on the peripheral nervous system and what on the brain? Science has an interest in this question for many reasons. In the long term, insights from this research could contribute to a better understanding of diseases such as ADHD and Parkinson's disease.

20 Nov 2019

Researchers investigate how sense of effort influences force perceptual bias

In a recent study published in PLOS One researchers from Hiroshima University and Nagoya Institute of Technology found that if you hold your car steering wheel at certain angles (1, 4, or 5 on the clock) then it's likely you're over or underestimating how much force you need to use to steer the car.

20 Nov 2019