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Scientists discover pathway that prevents buildup of Alzheimer's protein

St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. The report appeared online today in the journal Cell.

28 Jun 2019

Scientists reveal insights into how a common Alzheimer's risk gene disrupts brain cells

Insights into how a gene that increases the risk of Alzheimer's disease disrupts brain cells have been revealed by scientists.

27 Jun 2019

UB scientist wins new federal grant for follow-up "Jewels in Our Genes" study

During the "Jewels in Our Genes" study several years ago, Heather Ochs-Balcom and her team pinpointed four locations in the genome of African American women that may contain undiscovered genes that contribute to hereditary breast cancer.

27 Jun 2019

Researchers discover 'mystical' psychedelic compound in normal brains

In the past few years, thrill-seekers from Hollywood, Silicon Valley and beyond have been travelling to South America to take part in so-called Ayahuasca retreats.

27 Jun 2019

Study finds new cancer driver which is fast, furious and loud

The Fast and the Furious movie franchise meets the Fast N' Loud television series to define an oncogene that drives 35% of prostate cancers.

27 Jun 2019

Scientists reveal mechanism of tumor metastasis and tumor-suppressive role of UDP-glucose

Scientists from Dalian Institute of Chemical Physics and Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences revealed that UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.

27 Jun 2019

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

When it comes to using radiation against lung cancer, preliminary clinical studies were pretty clear: More is better.

27 Jun 2019

Researchers use genetically manipulated virus to combat prostate cancer

Researchers at the São Paulo State Cancer Institute in Brazil have succeeded in using a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer.

27 Jun 2019

Study provides new insight into development of asthma

Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways.

27 Jun 2019

Novel non-invasive test for diagnosing gut diseases

Gut diseases such as inflammatory bowel disease (IBD) are increasingly prevalent worldwide, especially in industrialized countries.

27 Jun 2019

Heat from nanoparticles zaps cancer cells from inside

Oregon State University researchers have come up with nanoclusters that are capable of reaching within tumours that are difficult to reach. The results of this breakthrough in cancer therapeutics were published in a study in the latest issue of the journal ACS Nano.

26 Jun 2019

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019

New study sheds light on the role of vitamin D in muscle cells

A recent study conducted at The Westmead Institute for Medical Research has shed light on the role of vitamin D in muscle cells.

26 Jun 2019

Scientists use advanced imaging to track brain tumor 'turncoats'

Glioblastomas, the deadliest type of brain tumor in adults, attract "turncoats." These are macrophages, a type of immune cell, which promote tumor progression and mask tumors from the immune system's scrutiny.

26 Jun 2019

New findings may help kick-start aging immune system

The thymus is the powerhouse producing the immune system's T cells, which combat infection in our body.

26 Jun 2019

New route to quickly transport subcutaneously administered antibodies into lymph nodes

Researchers from the University of Turku have discovered a new route that transports subcutaneously administered antibodies into lymph nodes in just a few seconds.

26 Jun 2019

How an orchestra of neurons control hunger pangs

A new study has shown that multiple neurons within the brain come together to regulate the need to eat and feeling of fullness, or satiety.

26 Jun 2019

Researchers challenge conventional understanding of cause of Parkinson's

An international team of researchers involving members of the University of Basel's Biozentrum challenges the conventional understanding of the cause of Parkinson's disease.

26 Jun 2019

Study reveals dual effects of new osteoporosis therapy on bone tissue

Sclerostin is a protein produced by osteocytes in the bone that inhibits bone formation. A recent analysis of results from a clinical trial reveals the beneficial effects of romosozumab, an antibody therapy that targets sclerostin, on bone tissue in postmenopausal women with osteoporosis.

26 Jun 2019

Low dose of endotoxin could have protective effect on men at risk of acute kidney injury

In a counterintuitive result, researchers found that giving male rats a low dose of the endotoxin lipopolysaccharide (LPS) prior to inducing a model of acute kidney injury (AKI) improved outcomes.

26 Jun 2019