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A promising strategy to overcome drug resistance developed by blood cancer cells

In a collaborative study published in Blood Advances, a research group led by Beate Heissig at Juntendo University and Yousef Salama at An Najah University report a strategy to overcome drug resistance developed by blood cancer cells.

27 Mar 2020

Maintaining VDR levels in pancreatic cells could protect against diabetes

Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of the disease.

27 Mar 2020

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Oncotarget Volume 11, Issue 12 reported that using the HL-60 human non-APL AML model where ATRA causes nuclear enrichment of c-Raf that drives differentiation/G0-arrest, the research team now observe that roscovitine enhanced nuclear enrichment of certain traditionally cytoplasmic signaling molecules and enhanced differentiation and cell cycle arrest.

26 Mar 2020

Stanford scientists describe potential transmission pathways of COVID-19

Much remains unknown about how SARS-CoV-2, the virus that causes COVID-19, spreads through the environment.

26 Mar 2020

NUI Galway study provides insights on neural basis of intelligence

An international collaborative study led by researchers from the NUI Galway provides findings on the neural basis of intelligence, otherwise known as general cognitive ability.

26 Mar 2020

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW-Madison study shows.

26 Mar 2020

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

The survival rates for patients with non-small cell lung cancer have improved greatly over the past decade thanks to several new targeted treatment options for patients.

26 Mar 2020

A quest to unlock the genetic code of SARS-CoV-2

How the novel coronavirus that causes COVID-19 made the leap from animals to humans is a puzzle that scientists are trying to solve as humanity comes to grip with the deadly pandemic sweeping the globe.

26 Mar 2020

Study suggests potential therapeutic strategy against diabetes

Maintaining vitamin D receptor levels in pancreatic cells that synthesize and secrete insulin (β cells) could contribute to protecting against the development of diabetes and counteract pancreatic cell damage caused by the progression of the disease.

26 Mar 2020

Experimental heart disease drug may treat chemo-resistant ovarian cancer

Most ovarian cancer starts in fallopian tubes. Then it sloughs from its site of origin and floats around in fluid until finding new sites of attachment. It's not easy for cancer cells to survive away from their moorings.

26 Mar 2020

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults.

26 Mar 2020

New type of immunotherapy shows promise for future treatment of ovarian cancer

Malignant ovarian cancer is insidious: Known and feared for vague and uncharacteristic symptoms that often mean the disease is discovered so late that on average only four out of six patients are still alive after five years.

26 Mar 2020

Lipid aids healing of scratches on the cornea

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Hotter temperatures linked to bad mental health

Hot days increase the probability that an average adult in the U.S. will report bad mental health, according to a study published on March 25, 2020 in the open-access journal PLOS ONE by Mengyao Li of the University of Georgia, and colleagues.

25 Mar 2020

Ankle exoskeletons can drastically reduce the energy cost of running, study finds

Running is great exercise but not everyone feels great doing it. In hopes of boosting physical activity - and possibly creating a new mode of transportation - engineers at Stanford University are studying devices that people could strap to their legs to make running easier.

25 Mar 2020

Highly purified fish oil therapy could prevent thousands of cardiovascular events

Researchers from the University of California, Irvine have conducted a statistical analysis that predicts more than 70,000 heart attacks, strokes and other adverse cardiovascular events could be prevented each year in the U.S. through the use of a highly purified fish oil therapy.

25 Mar 2020

Researchers aim to find the genetic basis of severe coronavirus infection in young people

Hundreds of clinicians worldwide are banding together in an effort to study some types of severe cases of the new coronavirus disease.

25 Mar 2020

Advancing CAR T-cell therapy for treatment of solid tumors

The full title of the research is "The study of the mechanisms of effectiveness of T-cells CAR-T towards solid tumors"; it was supported by nonprofit RakFond (Cancer Fund) and CyStoreLab (a resident of Skolkovo).

25 Mar 2020

Gero uses AI platform to identify potential anti-COVID-19 drugs

Gero, the leader in AI-driven drug discovery, has used its AI platform to identify the potential anti-COVID-19 drugs. Six of them have been approved, three were withdrawn, and the other nine have been already tested in clinical trials for other indications.

25 Mar 2020

Medical Science News

A promising strategy to overcome drug resistance developed by blood cancer cells

Maintaining VDR levels in pancreatic cells could protect against diabetes

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Stanford scientists describe potential transmission pathways of COVID-19

NUI Galway study provides insights on neural basis of intelligence

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

A quest to unlock the genetic code of SARS-CoV-2

Study suggests potential therapeutic strategy against diabetes

Experimental heart disease drug may treat chemo-resistant ovarian cancer

New 'more effective' stem cell transplant method could improve treatment of blood diseases

New type of immunotherapy shows promise for future treatment of ovarian cancer

Lipid aids healing of scratches on the cornea

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Hotter temperatures linked to bad mental health

Ankle exoskeletons can drastically reduce the energy cost of running, study finds

Highly purified fish oil therapy could prevent thousands of cardiovascular events

Researchers aim to find the genetic basis of severe coronavirus infection in young people

Advancing CAR T-cell therapy for treatment of solid tumors

Gero uses AI platform to identify potential anti-COVID-19 drugs

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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