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Researchers to explore the enigmatic role of unstructured protein in regulating circadian function

A new frontier in the science of circadian rhythms - whose disruption is linked to major diseases like cancer and diabetes - suggests a previously unknown mechanism at work in our daily biological cycle.

20 Nov 2018

Towards finding a druggable cancer target

It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer.

19 Nov 2018

New research center will pave way to better diagnosis and treatment of skin diseases

The new LEO Foundation Skin Immunology Research Center at the University of Copenhagen will pave the way to a better understanding, prevention and treatment of skin diseases that plague a quarter of the world's population.

19 Nov 2018

Replacement of dysfunctional microglia has therapeutic potential for neurodegenerative diseases

A new study by researchers at Karolinska Institutet supports the theory that replacement of dysfunctional immune cells in the brain has therapeutic potential for neurodegenerative diseases like ALS and Alzheimer's disease.

19 Nov 2018

Researchers identify gene vital for post-stroke recovery

Having certain specific variants of the PATJ gene predisposes to worse recovery from ischemic stroke. 7 out of 10 patients with these variants suffer severe sequelae three months after having a stroke, in other words, they are in a situation of dependence, compared to less than half of patients who do not present these variants.

19 Nov 2018

New glucose binding molecule could be key to better metabolic control for diabetics

Scientists from the University of Bristol have designed a new synthetic glucose binding molecule platform that brings us one step closer to the development of the world's first glucose-responsive insulin which, say researchers, will transform the treatment of diabetes.

19 Nov 2018

Researchers pinpoint brain region responsible for 'on-the-fly' decision-making

Researchers have pinpointed a part of the human brain responsible for “on-the-fly” decision-making. According to the findings published in JNeurosci, the anterior cingulate cortex integrates disparate information about the desirability and amount of an option to inform choice.

19 Nov 2018

Recreational drug may help people regain trust in others

The recreational drug known as ecstasy or molly may help people regain trust in others after being betrayed, suggests results of a controlled laboratory study, published in JNeurosci, of healthy men given a pure form of the substance.

From Society for Neuroscience 19 Nov 2018

Researchers find crucial inhibitory role for signal peptide in GluK1 trafficking

Glutamate is the major excitatory neurotransmitter in the brain, and the postsynaptic expression level of glutamate receptors is a critical factor in determining the efficiency of information transmission and the activity of the neuronal network.

19 Nov 2018

New solution to stop spread of brain cancer

The tissues in our bodies largely are made of fluid. It moves around cells and is essential to normal body function.

19 Nov 2018

Researchers identify molecule to fight myotubular myopathy

Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva, Switzerland, - working in collaboration with the University of Strasbourg, France, - have identified a molecule that not only greatly reduces the progression of the disease but also boosts life expectancy in animal models by a factor of seven.

19 Nov 2018

Molecular DNA analysis could facilitate more accurate prognosis, treatment of aggressive brain tumors

Meningiomas, a type of brain tumor, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and have high recurrence rates, i.e. there is a high risk of them coming back after treatment.

19 Nov 2018

Researchers develop novel mouse model to study immunomodulatory therapies

Because mice do not respond to immunomodulatory drugs, preclinical therapeutic and safety studies of the effects of IMiDs have not been possible in existing types of mice.

19 Nov 2018

New blood test developed for early diagnosis of ovarian cancer

Research on a bacterial toxin first discovered in Adelaide has led to the development a new blood test for the early diagnosis of ovarian cancer - a disease which kills over 1000 Australian women and 150,000 globally each year.

19 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

Experts debate over whether gut or brain is more important in regulating appetite

Whether gut or brain hormones are more important for the regulation of appetite and metabolism is not clearly defined. Imbalances in the control of appetite and metabolism can lead to obesity and diabetes, which have a negative impact on people's health and healthcare costs.

19 Nov 2018

New method studies how newborn baby's brain responds to being touched on face

A newborn baby's brain responds to being touched on the face, according to new research co-led by UCL.

19 Nov 2018

Human drugs alter cricket personality

Crickets that are exposed to human drugs that alter serotonin levels in the brain are less active and less aggressive than crickets that have had no drug exposure, according to a new study led by researchers from Linköping University. The findings have been published in Scientific Reports.

18 Nov 2018

Scientists discover new inhibitor that decreases lung inflammation

Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome - a life-threatening disease which affects thousands of people in the UK.

18 Nov 2018

New strategy to hinder emergence of antimicrobial-resistant pathogens

With many disease-causing bacteria ratcheting up their shields against current drugs, new tactics are vital to protect people from treatment-resistant infections.

17 Nov 2018