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Mouse models may not completely reflect severity of gonorrhea infection

There is an urgent need to develop a vaccine to prevent gonorrhea infection due to rapidly increasing incidence and growing antibiotic resistance.

4 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Looking deep inside the brain to accurately diagnose bipolar disorder and depression

New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression.

4 Sep 2018

Brain’s attention network plays key role in vision restoration after stroke, trauma

About one third of patients who have suffered a stroke end up with low vision, losing up to half of their visual field. This partial blindness was long considered irreversible, but recent studies have shown that vision training after optic nerve and brain damage can help restore or improve vision. A new study published in the journal Clinical Neurophysiology reports on key mechanisms of vision restoration: attention.

4 Sep 2018

Hormone link between diabetes and hypertension discovered

Physician researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.

4 Sep 2018

Researchers discover key aspect in pathogenesis of multiple sclerosis

A team of researchers the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain.

4 Sep 2018

Scientists discover ALS disease mechanism

A mechanism for how the disease ALS evolves has been discovered at Umeå University, Sweden. The discovery concerns how proteins with a defect structure spread the deformation to other proteins. This according to results in a new thesis.

4 Sep 2018

Eye-movement intervention reduces amygdala activity during recall of traumatic memory

Two human experiments published in JNeurosci demonstrate that a widely used yet controversial psychotherapy technique suppresses fear-related amygdala activity during recall of a traumatic memory.

From Society for Neuroscience 4 Sep 2018

Abnormal levels of metabolites can reliably predict lung disease in 9/11 firefighters

Abnormal levels of more than two dozen metabolites - chemicals produced in the body as it breaks down fats, proteins and carbohydrates - can reliably predict which Sept. 11 firefighters developed lung disease and which did not, a new analysis shows.

4 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts.

4 Sep 2018

UCLA biologists find 8,000 new antibiotic combinations to be effective

Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns.

3 Sep 2018

Genetic disruption strategy effectively stymies evolution of drug-resistant pathogens

A genetic disruption strategy developed by University of Colorado Boulder researchers effectively stymies the evolution of antibiotic-resistant bacteria such as E. coli, giving scientists a crucial leg up in the ongoing battle against deadly superbugs.

3 Sep 2018

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Anaplastic large-cell lymphomas are rare cancers of the white blood cells. New research from the international ERIA consortium, led by scientists in Vienna, has now shown that the same signaling pathway is essential to the growth of cancer cells in various forms of ALCL: TYK2 (tyrosine kinase 2, an important component of the immune system) prevents apoptotic cell death by increasing the production of Mcl1, a special type of protein belonging to the BCL2 family.

3 Sep 2018

Genetic mutations may drive tumor formation by blurring growth signals

Genetic mutations in a form of non-small cell lung cancer (NSCLC) may drive tumor formation by blurring cells' perception of key growth signals, according to a new laboratory study published August 31, 2018 in Science.

3 Sep 2018

Bile acids reduce desire for cocaine, finds study

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new study by researchers at Vanderbilt University Medical Center and the University of Alabama at Birmingham.

31 Aug 2018

Plant-derived substance could offer new option for treatment of obesity

A plant-derived substance widely used in traditional Chinese medicine has demonstrated promising weight loss effects.

31 Aug 2018

Early childhood growth patterns affect respiratory health

Children's growth in the first three years of life affects the development of their lungs and the risk of asthma at 10 years of age.

31 Aug 2018

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Study provides insights into how harmful white blood cells form during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues.

31 Aug 2018

Medical Science News

Mouse models may not completely reflect severity of gonorrhea infection

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

Looking deep inside the brain to accurately diagnose bipolar disorder and depression

Brain’s attention network plays key role in vision restoration after stroke, trauma

Hormone link between diabetes and hypertension discovered

Researchers discover key aspect in pathogenesis of multiple sclerosis

Scientists discover ALS disease mechanism

Eye-movement intervention reduces amygdala activity during recall of traumatic memory

Abnormal levels of metabolites can reliably predict lung disease in 9/11 firefighters

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

UCLA biologists find 8,000 new antibiotic combinations to be effective

Genetic disruption strategy effectively stymies evolution of drug-resistant pathogens

Scientists identify 'Achilles heel' of anaplastic large-cell lymphomas

Genetic mutations may drive tumor formation by blurring growth signals

Bile acids reduce desire for cocaine, finds study

Plant-derived substance could offer new option for treatment of obesity

Early childhood growth patterns affect respiratory health

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Study provides insights into how harmful white blood cells form during tuberculosis

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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