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Innovative drug delivery may alleviate Parkinson's symptoms and stop its progression

Parkinson's disease affects between 7 and 10 million people worldwide and the number of people diagnosed is soaring due to the ageing population.

10 Apr 2019

Psychosocial difficulties related to brain disorders much more similar than expected

Do you have difficulties remembering to do important things? A sense of everything moving too fast around you? Problems getting through the day because you just do not have the energy?

10 Apr 2019

Genetics may play a role in developing cancer therapy-induced cardiomyopathy

Recent advances in the development of cancer therapies have increased long-term survival and prognosis.

10 Apr 2019

HPV vaccination rates are low, especially in HIV prone populations

HPV vaccination rates in populations at high-risk of contracting HIV are particularly low, increasing the risk of HPV and HIV co-infection.

10 Apr 2019

Researchers map genetic mutation behind incurable disease

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis.

10 Apr 2019

Stimulating parvalbumin-containing cells causes surprising changes in blood volume, flow

Alzheimer's disease and schizophrenia are some of the most common brain disorders and have been associated with problems in cells that contain a type of protein, called parvalbumin.

10 Apr 2019

Scientists develop technique to clear abnormal tau protein from human neurons

Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders.

10 Apr 2019

Understanding imbalance in key neural pathway to help treat psychiatric disorders

Researchers at the University of California, Irvine have identified for the first time an imbalance in a key neural pathway that explains how some people reactivate negative emotional memories.

10 Apr 2019

New intradermal experimental model developed to study S. aureus infections

Infections caused by the Staphylococcus aureus bacteria through skin wounds cause thousands of deaths every year due to their fast transmission among large groups of people, such as hospitalized patients.

9 Apr 2019

Study suggests novel therapeutic strategy for ALS

In a study published online in Brain on April 1, researchers from Dr. XU Jin's lab at the Institute of Neuroscience of the Chinese Academy of Sciences and their collaborators revealed a new cellular mechanism for amyotrophic lateral sclerosis, suggested a novel therapeutic strategy targeting the RNA degradation pathway, and identified an asthma drug as a potential medication for ALS.

9 Apr 2019

New resource accelerates use of FISH techniques to study spatial organization of DNA in cells

Researchers at Karolinska Institutet present a publicly available resource that can accelerate the use of so-called FISH techniques for studying how the genome is spatially organised in the cell nucleus.

9 Apr 2019

New imaging technology will improve understanding of embryonic development

Soon after conception, an embryo's circulatory system connects to that of its mother. Complications that occur at this critical time can result in miscarriage or birth defects with long-term chronic conditions.

9 Apr 2019

Supplements provide no additional health benefits, conclude researchers

A new study has found that using dietary supplements such as calcium and vitamin D do not prolong life expectancy, and may increase cancer risk.

9 Apr 2019

Study reveals how higher educational attainment may stave off cognitive decline

Prefrontal brain regions linked to higher educational attainment are characterized by increased expression of genes involved in neurotransmission and immunity, finds a study of healthy older adults published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

Research may help explain why migraine is more common in women than men

Low doses of a peptide known for decades to be involved in migraine trigger pain responses in female but not male rodents, according to a new research published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

TGen review associates a gene with hepatocellular carcinoma

Hepatocellular carcinoma is a long medical name for the most common form of liver cancer, a malignancy whose incidence has nearly doubled over the past decade, making it the fastest growing type of cancer in the U.S., and the third-leading cause of cancer-related death worldwide.

9 Apr 2019

Early molecular signs of high-risk pregnancy revealed

Women who have healthy pregnancies tend to show distinct changes in the activities of immune genes starting early in pregnancy, while women who have complicated pregnancies tend to show clear departures from that pattern, according to a new study from a team led by researchers at Weill Cornell Medicine and Hospital for Special Surgery.

9 Apr 2019

New technique to test for viral infections discovered

A team of Colorado State University researchers has developed technology that can detect extremely small amounts of antibodies in a person's blood. Antibodies develop to infect cells or kill pathogens, essentially fighting off a bacteria or virus. The levels of antibodies in the blood can tell whether that person is sick.

9 Apr 2019

Experts detail efforts to improve seasonal and universal influenza vaccine

In a new series of articles, experts in immunology, virology, epidemiology, and vaccine development detail efforts to improve seasonal influenza vaccines and ultimately develop a universal influenza vaccine.

9 Apr 2019

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

On a normal day, the cells of a human liver do what they do best - making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile.

9 Apr 2019