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Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

Prolonged exposure to particulate matter in air pollution in the Los Angeles Basin triggered inflammation and the appearance of cancer-related genes in the brains of rats, a Cedars-Sinai study has found.

8 May 2018

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

A new and early target for treating pulmonary hypertension appears to be an enzyme that's normally key to energy production but destructive in the face of this high blood pressure inside your lungs.

8 May 2018

Scientists discover how protein molecules regulate formation of myelin sheaths

According to the Deutsche Multiple Sklerose Gesellschaft, around 200,000 people in Germany suffer from multiple sclerosis- a serious neurological condition that has no known cure.

8 May 2018

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Cancer is most devastating when it metastasizes--when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor.

8 May 2018

Using human induced pluripotent stem cells for therapeutic drug testing

Researchers at Li Ka Shing Faculty of Medicine of The University of Hong Kong have successfully demonstrated the use of human induced pluripotent stem cells from patients' skin cells for therapeutic drug testing.

8 May 2018

Study identifies new biomarker for early lung cancer diagnosis

High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.

8 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Research shows possibility of new ways to address blood-brain barrier dysfunction in epilepsy

New findings from the University of Kentucky published in the Journal of Neuroscience demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy.

8 May 2018

Cancer scientists confirm oligometastasis hypothesis

In 1995, two University of Chicago-based cancer specialists suggested there was an intermediate state - somewhere between curable localized cancers and lethal widespread disease - for patients with metastatic cancer.

7 May 2018

Study identifies molecule that may be critical to repair of white matter

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the brains of preterm babies.

7 May 2018

Novel 3D cancer model to accelerate development of new and better treatments

A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a three-dimensional model of a cancer tumor that he says has the potential to replicate the complex nature and behavior of a real tumor.

7 May 2018

Research shows that amniotic fluid contains stem cells of kidney origin

Amniotic fluid, the liquid surrounding the fetus, can be routinely obtained without harming the mother or the baby. Previously, Prof. Dr. Adjaye's team and others demonstrated that amniotic fluid contains mesenchymal stem cells with great differentiation and regenerative potential.

7 May 2018

Brain-imaging study adds new evidence that infants track other people's beliefs

A brain-imaging study offers new support for the idea that infants can accurately track other people's beliefs.

7 May 2018

Brain activity, reactivity associated with depression and negative feelings in diabetics

For millions of Americans who are obese and living with diabetes or prediabetes, feelings of sadness, anger and anxiety are often part of daily life.

7 May 2018

Researchers uncover role of ROS in clearing dead cells

If dead cells accumulate in the body, they can contribute to inflammation and pre-dispose individuals to multiple chronic inflammatory conditions such as rheumatoid arthritis, cardiovascular diseases, Crohn's disease or lupus by uncharacterized pathways.

7 May 2018

Medical Science News

Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Scientists discover how protein molecules regulate formation of myelin sheaths

New research identifies critical function of PDK1 pathway that contributes to cancer metastasis

Using human induced pluripotent stem cells for therapeutic drug testing

Study identifies new biomarker for early lung cancer diagnosis

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Research shows possibility of new ways to address blood-brain barrier dysfunction in epilepsy

Cancer scientists confirm oligometastasis hypothesis

Study identifies molecule that may be critical to repair of white matter

Novel 3D cancer model to accelerate development of new and better treatments

Research shows that amniotic fluid contains stem cells of kidney origin

Brain-imaging study adds new evidence that infants track other people's beliefs

Brain activity, reactivity associated with depression and negative feelings in diabetics

Researchers uncover role of ROS in clearing dead cells

Strong pupillary light reflex in infants linked to later autism diagnosis

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Placental hormone level rises during pregnancy and reaches peak as fetuses approach full term

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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