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Key signaling protein in Huntington's disease found to have deleterious effects on heart function, shows study

Researchers investigating a key signaling protein in Huntington's disease describe deleterious effects on heart function, going beyond the disease's devastating neurological impact.

25 Apr 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

Experimental drug for rheumatoid arthritis prevents side effect of stem cell transplants

An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows.

25 Apr 2018

Study shows gene variations associated with malaria risk

Many people of African heritage are protected against malaria by inheriting a particular version of a gene, a large-scale study has shown.

25 Apr 2018

Bariatric surgery successes pave way for new type 2 diabetes treatment

Bariatric surgery has long yielded almost immediate health benefits for patients with type 2 diabetes, and new findings on the reasons for remission may be the key to developing drug alternatives to surgery.

25 Apr 2018

Study explains why intense exercise curbs appetite

Ever wonder why intense exercise temporarily curbs your appetite? In research described in today's issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head - more specifically, your arcuate nucleus.

25 Apr 2018

Preantral zinc deficiency may affect fertility months

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility.

24 Apr 2018

Researchers identify novel pathway in development of AML with poor prognosis

Acute myeloid leukemia is a cancer of the blood and bone marrow that comprises 1% of all new cancer cases and almost 2% of cancer deaths in the U.S. The five-year survival rate for the disease is less than 20%.

24 Apr 2018

Stress may induce neurotransmitter switching that contributes to chemical imbalances in the brain

Five years ago, a team of University of California San Diego neurobiologists published surprising findings describing how rats' brain cells adopted new chemical codes when subjected to significant changes in natural light exposure--much as humans suffer from "winter blues," the type of depression known as seasonal affective disorder.

24 Apr 2018

Study highlights potential of stem cells derived from adults in regenerative medicine

Donor age does not appear to influence the functionality of stem cells derived from adult body tissues, concludes a new review. The analysis of research on induced pluripotent stem cells (iPSCs) finds that not only are typical signs of aging reversed in iPSCs, but cells derived from both older and younger donors show the same ability to differentiate into mature body cells.

24 Apr 2018

Elevated immune function during childhood linked to stunted growth

Elevated immune function during childhood results in as much as 49 percent growth reduction in Ecuador's indigenous Shuar population, researchers reported in the Proceedings of the National Academy of Sciences.

24 Apr 2018

Researchers discover new gene associated with aortic aneurysms

An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, the researchers shed light on mechanisms not previously known to be associated with this devastating disease.

24 Apr 2018

Hippo pathway plays essential role in embryonic development of the mouse heart

Using a technology that provides a 'high-resolution view' of the status of individual cells, a team of researchers has gained new insights into the embryonic development of the mouse heart.

24 Apr 2018

EMBL scientists develop new illumination method to manage neuropathic pain

Imagine that the movement of a single hair on your arm causes severe pain. For patients with neuropathic pain - a chronic illness affecting 7 to 8% of the European population, with no effective treatment - this can be a daily reality.

24 Apr 2018

Imagined and real movements have similar brain mechanisms, research suggests

A new study from Karolinska Institutet shows that imagined movements can change our perception in the same way as real, executed movements do.

24 Apr 2018

Researchers find role of iron storage gene in slowing down prostate cancer growth

An abnormally high level of iron in the body is associated with prostate cancer, and researchers from the Cancer Science Institute of Singapore at the National University of Singapore may have uncovered the mechanism to explain this link.

24 Apr 2018

Scientists develop tissue-engineered models to better understand cancer metastases

Cancer that has spread, or metastasized, from its original site to other tissues and organs in the body is a leading cause of cancer death.

24 Apr 2018

Researchers design creative new approach to regenerate injured hearts

Heart disease is a major global health problem--myocardial infarction annually affects more than one million people in the U.S. alone, and there is still no effective treatment.

24 Apr 2018

Alcoholic drinks affect oral bacteria tied to diseases

When compared with nondrinkers, men and women who had one or more alcoholic drinks per day had an overabundance of oral bacteria linked to gum disease, some cancers, and heart disease. By contrast, drinkers had fewer bacteria known to check the growth of other, harmful germs.

24 Apr 2018

Adipose-derived mesenchymal stem cells combined with fibrin matrix influences restoration of motor functions

The research team used model spinal cord injuries in rats for their purposes. As a result, it was found out that therapy by adipose-derived mesenchymal stem cells combined with fibrin matrix influences the restoration of motor functions.

24 Apr 2018