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Study reveals the link between low fitness and increased waist circumference

A new study published in the open-access journal PLOS ONE, identified an inverse correlation between low fitness and large waist size as well as a higher degree of inflammation.

18 Jan 2018

Modular gene enhancers may be suitable target in treatment of blood cancer

Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer.

18 Jan 2018

Sex steroid hormone fluctuations may have direct effects on eye physiology and AMD

Gender-based differences may influence several ocular conditions, suggesting that fluctuations in sex steroid homeostasis may have direct effects on eye physiology and the pathogenesis of conditions like Age-Related Macular Degeneration.

18 Jan 2018

Researchers reveal potential of multivalent antibodies for HIV prevention, treatment and cure

The ability of HIV to mutate has been a major challenge to vaccine development. As the body produces antibodies to target the outer HIV envelope protein, this protein changes, thwarting the circulating antibodies' ability to neutralize it.

18 Jan 2018

New biomaterials-based system improves T-cell production

T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, chemical-based approaches.

18 Jan 2018

Potential male birth control pill could be developed from arrow poison

Women have many options for oral contraceptives that are safe, effective and reversible, but despite decades of research, men have none.

18 Jan 2018

MSU scientists seek to identify brain mechanisms related to psychosis

Why do some people who are diagnosed with schizophrenia experience psychosis, a disconnection from reality that can make them believe their actions are being controlled by aliens or the government?

18 Jan 2018

Study suggests movement as accurate method to diagnose neurodevelopmental disorders

A new study led by researchers at Indiana University and Rutgers University provides the strongest evidence yet that nearly imperceptible changes in how people move can be used to diagnose neurodevelopmental disorders, including autism.

18 Jan 2018

Analysis finds overlooked crucial factor in determining prognosis for DIPGs

The prognosis for all children diagnosed with an aggressive brain tumor known as diffuse intrinsic pontine glioma and similar tumors has been mostly the same: dismal.

18 Jan 2018

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by prof. Savvas Savvides has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease.

18 Jan 2018

Signaling molecules likely involved in concussions, rodent studies show

Traumatic brain injuries, whether suffered from a blow on the football field or the battle field, can be devastating, leading to disability and shortened lives.

18 Jan 2018

Findings reveal conventional cancer therapy as double-edged sword

Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

18 Jan 2018

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin.

18 Jan 2018

New vaccine approach offers effective protection against tuberculosis

A unique platform that resulted in a promising HIV vaccine has also led to a new, highly effective vaccine against tuberculosis that is moving toward testing in humans.

18 Jan 2018

Researchers find new way to halt growth of breast cancer cells

An international team of researchers led from Karolinska Institutet and Science for Life Laboratory in Sweden have found a new way of halting the growth of breast cancer cells.

18 Jan 2018

Study identifies new target for treatment of depression

According to the World Health Organization more than three hundred million people worldwide are affected by major depressive disorder. Unfortunately, the antidepressants commonly used to treat them only work for 50% of the population.

18 Jan 2018

Scientists discover possible cause of colonial-era epidemic in Mexico

An international team of scientists has identified the possible cause of a colonial-era epidemic in Mexico. Using new techniques in ancient DNA research, experts from the Max Plank Institute, Harvard University and the Mexican National Institute of Anthropology and History, identified Salmonella enterica Paratyphi C in skeletons left behind from the 1545-1550 cocoliztli epidemic.

17 Jan 2018

Three-dimensional organization of genome plays key role in gene expression, cell fate

Scientists have long been reading the code of life - the genome -, as a sequence of letters but now researchers have also started exploring its three-dimensional organization.

17 Jan 2018

Scientists identify six new gene regions that may help treat type 1 diabetes

Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.

17 Jan 2018

EXD2 enzyme facilitates protein production in mitochondria

Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for the majority of energy generation.

17 Jan 2018