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Novel 3D cancer model to accelerate development of new and better treatments

A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a three-dimensional model of a cancer tumor that he says has the potential to replicate the complex nature and behavior of a real tumor.

7 May 2018

Research shows that amniotic fluid contains stem cells of kidney origin

Amniotic fluid, the liquid surrounding the fetus, can be routinely obtained without harming the mother or the baby. Previously, Prof. Dr. Adjaye's team and others demonstrated that amniotic fluid contains mesenchymal stem cells with great differentiation and regenerative potential.

7 May 2018

Brain-imaging study adds new evidence that infants track other people's beliefs

A brain-imaging study offers new support for the idea that infants can accurately track other people's beliefs.

7 May 2018

Brain activity, reactivity associated with depression and negative feelings in diabetics

For millions of Americans who are obese and living with diabetes or prediabetes, feelings of sadness, anger and anxiety are often part of daily life.

7 May 2018

Researchers uncover role of ROS in clearing dead cells

If dead cells accumulate in the body, they can contribute to inflammation and pre-dispose individuals to multiple chronic inflammatory conditions such as rheumatoid arthritis, cardiovascular diseases, Crohn's disease or lupus by uncharacterized pathways.

7 May 2018

Strong pupillary light reflex in infants linked to later autism diagnosis

A new study published in Nature Communications shows that infants who are later diagnosed with autism react more strongly to sudden changes in light.

7 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Placental hormone level rises during pregnancy and reaches peak as fetuses approach full term

Just as a runner steadily builds up endurance in order to peak at just the right time, the placenta carefully calibrates how much of the hormone allopregnanolone it produces during pregnancy.

7 May 2018

Researchers discover how key brain receptor can function in hostile environment

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate.

7 May 2018

Discovery could be used as starting point for development of new antibiotics

According to the WHO, around 700,000 people die every year as a result of antibiotic resistance. In Germany, around 6,000 people die every year because treatment with antibiotics is not effective.

7 May 2018

Researchers uncover protein linked to breast cancer metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.

7 May 2018

Stimulant use may negatively affect health of HIV-positive persons

A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants, such as methamphetamine, can negatively affect the health of HIV-positive persons even when they are adhering to medical treatment.

4 May 2018

Study shows advantages of using decellularized muscle to promote tissue regeneration

A new comparative study showed the advantages of using donor decellularized muscle to promote functional tissue regeneration at the site of bulk skeletal muscle loss due to trauma or surgery.

4 May 2018

Dancer's brains show fast response during sudden changes in music

Neuroscience has studied music for decades, and it has been found to activate both the cortical and deeper brain areas. Neuroscience of dance, instead, is a young but quickly growing field.

4 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

Researchers uncover novel approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer.

4 May 2018

Researchers shed new light on identity of brain stem cells

The human nervous system is a complex structure that sends electrical signals from the brain to the rest of the body, enabling us to move and think. Unfortunately, when brain cells are damaged by trauma or disease they don't automatically regenerate. This can lead to permanent disability.

4 May 2018

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

4 May 2018

Unexpected discovery could improve detection of malaria infections

While the global health community has made great strides toward eradicating malaria through prevention and treatment strategies, rapid and inexpensive methods to diagnose submicroscopic malaria in individuals who have no clinical symptoms and undetectable levels of disease-causing parasites in their blood remain an unmet need.

4 May 2018

Surprising discovery offers new model for studying role of gap junctions in the brain

The same kind of neurons can have completely different wiring diagrams in the rat and mouse, as mice lack intercellular molecular channels known as gap junctions, researchers at Karolinska Institutet report in the scientific journal eLIFE.

4 May 2018