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Lysosomal activity in worms linked to transgenerational extension of lifespan

In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend the worm's life by up to 60 percent.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

Alcohol raises dementia risk at every level of drinking, genetic study shows

Researchers using two major cohorts and Mendelian randomization found that alcohol consumption, whether light or heavy, raises the risk of dementia. Genetic evidence shows no safe level of drinking, challenging the belief that moderate intake protects brain health.

25 Sep 2025

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

This pilot study found that urinary metabolites of organophosphate pesticides were linked to reduced sperm motility in healthy young men, though results were preliminary. Oxidative stress did not explain the association, suggesting other biological pathways may be involved.

25 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a groundbreaking brain imaging technique that reveals how tiny blood vessels in the brain pulse with each heartbeat-changes that may hold clues to aging and diseases such as Alzheimer's.

25 Sep 2025

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Scientists at the NYU Pain Research Center have identified which receptor in prostaglandins-the hormone-like substance targeted by common painkillers-causes pain but not inflammation.

25 Sep 2025

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

25 Sep 2025

UPR modulators show promise in treating cancer-related bone disease

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation.

25 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

AstroCapsules offer a new way to reduce brain inflammation

Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease.

25 Sep 2025

New study suggests a connection between soft drinks and depression via the microbiome

A new study involving the German Center for Diabetes Research (DZD) provides strong evidence that sugary drinks affect not only metabolic but also mental health – especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.

25 Sep 2025

Colorectal cancer first presents with unexplained strokes and blood clots

A new case report was published in Volume 12 of Oncoscience on September 15, 2025, titled "When strokes reveal a hidden malignancy: An atypical case of metastatic colorectal cancer with extensive thromboembolism."

25 Sep 2025

Genetic modification enhances "living drugs" for blood cancers

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, with a "chimeric antigen receptor" (CAR) enables them to specifically recognize and attack cancer cells.

25 Sep 2025

Pioneering 3D printing technique makes realistic surgical models

Researchers at the University of Minnesota Twin Cities have successfully 3D printed lifelike human tissue structures that can be used for medical training for surgeons and doctors.

25 Sep 2025

Study shows dementia patients exposed to pollution had longer telomeres

Researchers studying a Swedish aging cohort found no overall link between air pollution and telomere shortening, a key marker of biological aging. Intriguingly, dementia patients exposed to higher pollution showed longer telomeres, though results were statistically non-significant.

24 Sep 2025

Fresh donor milk linked to reduced gastrointestinal complicatoins in premature infants

A study from the Medical University of South Carolina, published in the Journal of Parenteral and Enteral Nutrition, reveals that shorter storage durations of donor human milk are linked to reduced gastrointestinal complicatoins in premature infants, including necrotizing enterocolitis.

24 Sep 2025

Researchers uncover how chromosome crossovers protect fertility

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

24 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

How many cities will face unlivable heat by 2100?

Researchers assessed future urban heat exposure and adaptive capacity in 1,563 major cities worldwide, using high-resolution climate projections, local climate zones, and socioeconomic indicators. By 2100, hundreds of millions may live in cities exceeding habitability thresholds, with adaptation gaps greatest in low-income regions.

24 Sep 2025

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Medical Science News

Lysosomal activity in worms linked to transgenerational extension of lifespan

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Alcohol raises dementia risk at every level of drinking, genetic study shows

Organophosphate pesticide exposure linked to reduced sperm quality in healthy men

Healthy habits linked to younger brain age

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Discovery of EP2 receptor opens path to pain relief without blocking inflammation

Study uncovers how lymphatic endothelial cells assist in generating robust immune memory

UPR modulators show promise in treating cancer-related bone disease

Targeting TGF-β signaling as a strategy to treat liver fibrosis

AstroCapsules offer a new way to reduce brain inflammation

New study suggests a connection between soft drinks and depression via the microbiome

Colorectal cancer first presents with unexplained strokes and blood clots

Genetic modification enhances "living drugs" for blood cancers

Pioneering 3D printing technique makes realistic surgical models

Study shows dementia patients exposed to pollution had longer telomeres

Fresh donor milk linked to reduced gastrointestinal complicatoins in premature infants

Researchers uncover how chromosome crossovers protect fertility

Scientists map step-by-step activation of brain receptors

How many cities will face unlivable heat by 2100?

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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