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Oral microbiota transmission linked to shared depression and anxiety in couples

Oral microbiota dysbiosis and altered salivary cortisol levels have been linked to depression and anxiety.

23 May 2025

Muscle quality linked to cognitive health in middle age

Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders.

23 May 2025

Autophagy-based mechanism provides insight into Parkinson’s disease protein secretion

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells.

23 May 2025

Radiometer expands clinical intelligence software suite with AI-enabled tool to improve triage in overcrowded Emergency Departments

With TriageGO, Radiometer introduces an innovative AI tool that streamlines patient prioritization in emergency settings, improving care efficiency and safety.

From Radiometer Medical 23 May 2025

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Powerful new toolkit targets vision loss in advanced retinal degeneration

Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes needed for their function and survival.

23 May 2025

FOXP4 gene variants reveal new genetic link to long COVID risk

Researchers have identified genetic variants in the FOXP4 gene that significantly increase the risk of developing long COVID, independently of COVID-19 severity. The study also reveals that ancestry, smoking, and other factors contribute to the complex genetics of long COVID.

23 May 2025

Air pollution’s chemical punch alters immune markers in pregnant women, study finds

Personal exposure to nitrogen dioxide and the oxidative potential of fine particulate matter (PM2.5), but not PM2.5 mass, influenced immune biomarker levels in pregnant women. These findings suggest that the chemical reactivity of air pollutants may play a key role in maternal and fetal immune health.

22 May 2025

Researchers prolong ketamine’s antidepressant benefits to two months

Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any given time, and up to 20 percent will exhibit MDD symptoms over their lifetimes.

22 May 2025

Machine learning tool identifies metabolic clues in colorectal cancer

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

22 May 2025

Mild winter temperatures offer surprising mental health benefits

Higher ambient temperatures during the cold season were linked to reduced stress, improved life satisfaction, better self-reported health, and less loneliness in a large Swiss population study. While effects were modest at the individual level, they highlight the broader mental health impacts of seasonal temperature changes.

22 May 2025

Blood markers offer hope for early detection of teen depression

Using a novel lab method they developed, McGill University researchers have identified nine molecules in the blood that were elevated in teens diagnosed with depression.

22 May 2025

Cutting back on sugary drinks may protect men’s fertility, review finds

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, potentially impairing male reproductive health. This narrative review highlights dose-response effects, mechanisms, and research gaps, calling for further studies on diverse populations.

22 May 2025

Metabolite profiles in spinal fluid predict mortality in tuberculous meningitis

Radboudumc researchers Kirsten van Abeelen, Edwin Ardiansyah, Sofiati Dian, Vinod Kumar, Reinout van Crevel and Arjan van Laarhoven used metabolomics to study cerebrospinal fluid (CSF) samples from tuberculous meningitis patients in Vietnam and Indonesia, with long-standing collaborators from Bandung and Jakarta (Indonesia), the Broad Institute (Boston) and the Oxford University Research Unit in Ho Chi Minh City (Vietnam).

22 May 2025

Endurance training leads to significant drops in vascular resistance and diastolic blood pressure

Eight months of supervised marathon training in Finnish adults led to moderate reductions in peripheral diastolic blood pressure, systemic vascular resistance, and extracellular water volume. Central (aortic) blood pressure showed a non-significant decline, highlighting the specific impact of exercise on vascular health.

22 May 2025

Mediterranean eating habits help European children fight genetic obesity risk

A large European cohort study found that adherence to the Mediterranean diet mitigates the impact of genetic risk for obesity in children, especially in early childhood. High consumption of vegetables and legumes was linked to lower obesity risk, regardless of genetic predisposition.

22 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Researchers establish a new golden standard for human lactation studies

Women who choose to stop treatment during pregnancy and breastfeeding are putting their health at risk, and have to weigh their desire to have children and breastfeed against a risk that we know very little about.

22 May 2025

Meta analysis highlights prognostic role of circPVT1 in solid tumors

circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated.

22 May 2025

New AI blood test tracks pancreatic cancer treatment response

An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient's blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.

22 May 2025