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TSRI scientists discover potential drug candidate to suppress pain and itch

In a new study, scientists from the Florida campus of The Scripps Research Institute have identified a possible drug candidate that suppresses pain and itch in animal models.

1 Dec 2016

Researcher explores link between PTSD and repeated alcohol use

As families gather for the holidays this year, many will reminisce, sharing fond memories as they break bread and pass the cranberry sauce.

1 Dec 2016

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread.

1 Dec 2016

No link exists between maternal flu and increased child autism risk, says study

A study has found no association between a mother catching the flu during pregnancy and their child having an increased risk of autism spectrum disorder (ASD).

1 Dec 2016

How old is your heart?

There have been a number of ways to measure the biological health and age of your heart, which has been done conventionally in the past. Blood pressure is one indicator. Other risk indicators include family history of heart disease, level of cholesterol and exercise testing, where you can get heart rate...

From iHeart - VitalSines International Inc. 1 Dec 2016

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks.

1 Dec 2016

New mouse model provides key information for understanding cortical circuit development

A day by day log of cortical electric activity in the mouse visual cortex was published in the Journal of Neuroscience by George Washington University researcher Matthew Colonnese, Ph.D.

1 Dec 2016

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers.

1 Dec 2016

New global network to explore link between genes and environmental factors to tackle health challenges

A new global network linking leading research centres across the world has launched today to tackle some of the most pressing global health challenges of our time such as autism, cancer, diabetes and dementia.

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Newborns with low levels of vitamin D may more likely develop multiple sclerosis in later life

Babies born with low levels of vitamin D may be more likely to develop multiple sclerosis (MS) later in life than babies with higher levels of vitamin D, according to a study published in the November 30, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

30 Nov 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol.

30 Nov 2016

Scientists synthesize antitumor compound to combat chemoresistant cancer

A team of scientists from N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences, N. K. Kol'tsov Institute of Developmental Biology of the RAS, and Immune Pharmaceuticals LLC led by MIPT's Prof. Alexander Kiselyov has synthesized an antitumor compound that could be used to fight chemoresistant cancer.

30 Nov 2016

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

In a new study published online today in the journal Neurology, a research team led by neurologists at Beth Israel Deaconess Medical Center and neuropsychologists at Boston University has shown that when patients with Parkinson's disease experience a drop in blood pressure upon standing up - a condition known as orthostatic hypotension (OH) - they exhibit significant cognitive deficits.

30 Nov 2016

Study finds persistent cortical thinning in former collegiate football players

A growing body of research continues to raise concerns about the effects of head trauma sustained while participating in popular contact sports, particularly football.

30 Nov 2016

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients.

30 Nov 2016

Biomedical scientist develops new way to create micro muscles for testing muscle efficiency

A biomedical research scientist is taking the lead in the creation of muscle cells and micro muscles to test muscle efficiency in the laboratory - and he is able to carry out this new and innovative work thanks to the support he has received to get him back into science after a career break.

30 Nov 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function.

30 Nov 2016

Medical Science News

TSRI scientists discover potential drug candidate to suppress pain and itch

Researcher explores link between PTSD and repeated alcohol use

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

No link exists between maternal flu and increased child autism risk, says study

How old is your heart?

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

New mouse model provides key information for understanding cortical circuit development

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

New global network to explore link between genes and environmental factors to tackle health challenges

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Newborns with low levels of vitamin D may more likely develop multiple sclerosis in later life

Type 2 diabetes drug may someday help combat breast and ovarian cancers

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

Scientists synthesize antitumor compound to combat chemoresistant cancer

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

Study finds persistent cortical thinning in former collegiate football players

TGen and City of Hope collaborate to accelerate precision medicine research

Biomedical scientist develops new way to create micro muscles for testing muscle efficiency

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

Scientists identify cell-surface receptor for progranulin

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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