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LMU researchers show how genetic variant in people of African ancestry modulates immune cells

A genetic variant that is particularly prevalent in people of African ancestry confers protection against malaria. LMU researchers have now shown how it modulates the properties of white blood cells that play a major role in immune defenses and inflammation.

1 Jun 2017

Scientists discover unexpected mechanism behind chronic nerve pain

It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain.

1 Jun 2017

Study reveals how puberty hormones may impede flexible youthful learning

A University of California, Berkeley, study of mice reveals, for the first time, how puberty hormones might impede some aspects of flexible youthful learning.

1 Jun 2017

Researchers find new way to block type 1 diabetes

Researchers at The Jackson Laboratory, Cyteir Therapeutics and collaborating institutions have found a way to protect beta cells from destruction -- achieving a longtime, elusive goal that could lead to therapies preventing type 1 diabetes (T1D).

1 Jun 2017

New study establishes link between prenatal stress and onset of eating disorders

Stress affects the body and can trigger illness -- from psychiatric disorders to heart disease. Humans are exposed to stress at different intensities throughout life -- as children, in adolescence, and in old age. But when is the impact of stress on our systems most powerful? Many researchers maintain that the critical effect occurs prenatally, inside the womb.

1 Jun 2017

Researchers discover new class of compounds that inhibit bacterial DNA gyrase

An international team of scientists have discovered a new class of compounds that inhibit bacterial DNA gyrase.

1 Jun 2017

Scientists identify new gene that prompts muscle stem cells to fuse together

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

1 Jun 2017

Impaired ability to understand social cues may be linked to brain changes in people with MS

For people with multiple sclerosis (MS), an impaired ability to understand how others feel and think may be linked to subtle brain changes, according to a study published in the May 31, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

1 Jun 2017

Chronic pain may occur when receptors migrate from nerve cell's surface to inner chambers

A study led by Columbia University Medical Center has shown that chronic pain may occur when pain receptors migrate from the nerve cell's surface to the cell's inner chambers, out of the reach of current pain medications.

1 Jun 2017

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Understanding how memories are made, retrieved, and eventually fade over a lifetime is the stuff of poems and song. To medical researchers, solving the mysteries of memory is even more elusive.

1 Jun 2017

Study reveals key role of gut microbiota in treatment with classic diabetes medication

A clearer picture of how the classic diabetes medication metformin works has emerged. A recent study at Sahlgrenska Academy and University of Girona indicates that the clinical effect - control of blood glucose - is achieved through modulation of the gut microbiota.

1 Jun 2017

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Researchers from Belgium led by Prof. Dirk Elewaut of the VIB-UGent Center for Inflammation Research and the team of Prof. Vanderkerken and Prof. Menu at the Hematology and Immunology lab of the VUB uncovered a new way to enhance the function of a specific type of immune cell that destroys tumors in multiple myeloma, a form of bone marrow cancer considered incurable.

1 Jun 2017

Cholesterol shown to have clear effect on lung surface properties

Cholesterol, a naturally occurring compound at the lung surface, has been shown to have a clear effect on the properties of this nanoscale film that covers the inside of our lungs.

1 Jun 2017

Researchers gain new insights into factors crucial for STIM1 activation

Triggered by decreases in ER Ca2+ level, conformational changes of the endoplasmic reticulum (ER) luminal domain in STIM1 would switch on its cytoplasmic domain (CT) to engage and gate ORAI channels on plasma membrane, resulting in Ca2+ influx.

1 Jun 2017

Scientists identify 100 genes that provide new entry points into understanding human memory

Scientists have identified more than 100 genes linked to memory, opening new avenues of research to better understand memory processing in the human brain.

1 Jun 2017

New method combines organoid technology with bioengineering to build better brains

A few years ago, Jürgen Knoblich and his team at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) have pioneered brain organoid technology. They developed a method for cultivating three-dimensional brain-like structures, so called cerebral organoids, in a dish.

1 Jun 2017

Single protein allows mycobacteria to generate diverse populations and avoid TB drugs, research shows

Subgroups of tuberculosis (TB)-causing bacteria can persist even when antibiotics wipe out most of the overall population. The need to eliminate these persistent subpopulations is one reason why TB treatment regimens are so lengthy.

1 Jun 2017

Researchers discover molecular signaling circuit that regulates autophagy

Autophagy is the recycling process by which our cells keep themselves young. They continually break down and renew small parts of themselves in a kind of self-digestion; this helps to counteract harmful deposits which may form.

1 Jun 2017

Repeated exposure to anesthesia early in life impairs visual recognition memory

Repeated exposure to a common anesthesia drug early in life results in visual recognition memory impairment, which emerges after the first year of life and may persist long-term, according to a study from the Icahn School of Medicine at Mount Sinai and published online May 31 in the British Journal of Anaesthesia.

31 May 2017

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

Scientists have, for the first time, characterized the molecular markers that make the brain's front lines of immune defense--cells called microglia--unique.

31 May 2017

Medical Science News

LMU researchers show how genetic variant in people of African ancestry modulates immune cells

Scientists discover unexpected mechanism behind chronic nerve pain

Study reveals how puberty hormones may impede flexible youthful learning

Researchers find new way to block type 1 diabetes

New study establishes link between prenatal stress and onset of eating disorders

Researchers discover new class of compounds that inhibit bacterial DNA gyrase

Scientists identify new gene that prompts muscle stem cells to fuse together

Impaired ability to understand social cues may be linked to brain changes in people with MS

Chronic pain may occur when receptors migrate from nerve cell's surface to inner chambers

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Study reveals key role of gut microbiota in treatment with classic diabetes medication

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Cholesterol shown to have clear effect on lung surface properties

Researchers gain new insights into factors crucial for STIM1 activation

Scientists identify 100 genes that provide new entry points into understanding human memory

New method combines organoid technology with bioengineering to build better brains

Single protein allows mycobacteria to generate diverse populations and avoid TB drugs, research shows

Researchers discover molecular signaling circuit that regulates autophagy

Repeated exposure to anesthesia early in life impairs visual recognition memory

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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