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MSU scientists identify antioxidant system that backs up liver during crisis

Scientists from Montana State University and Sweden have discovered an antioxidant system that helps sustain the liver when other systems are missing or compromised.

23 Mar 2015

ISSCR statement calls for moratorium nuclear genome editing of human germ line

In a statement released yesterday, the International Society for Stem Cell Research called for a moratorium on attempts at clinical application of nuclear genome editing of the human germ line to enable more extensive scientific analysis of the potential risks of genome editing and broader public discussion of the societal and ethical implications.

23 Mar 2015

Scientists use optical radiation to treat cancer at the cellular level

Wanting to achieve early cancer detection, a group of scientists from the Center for Research in Optics (CIO) of Guadalajara, in Mexico, seeks to address the problem from the cell with optical radiation.

23 Mar 2015

Discovery can help stop emergence of age-related neurodegenerative diseases

As medicine has improved, increasing our ability to treat disease, so our longevity. The deterioration of the body with age, though, is a whole other matter.

23 Mar 2015

Brief sleep can significantly improve memory performance

Generations of school students have gone to bed the night before a maths exam or a vocabulary test with their algebra book or vocabulary notes tucked under their pillow in the hope that the knowledge would somehow be magically transferred into their brains while they slept.

23 Mar 2015

Existing drugs could help prevent deadly familial stomach and lobular breast cancers

Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by cancer genetics researchers at New Zealand's University of Otago.

23 Mar 2015

Copenhagen researchers develop secure way of measuring apo-M protein in human blood

Researchers from the University of Copenhagen are the first in the world to develop a secure way of measuring the important protein apo-M. This could prove relevant for research into diseases such as diabetes, arteriosclerosis and sclerosis.

23 Mar 2015

Researchers identify new role for VEGFA that may help target metastatic neuroblastoma

Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption.

23 Mar 2015

New analysis of medieval cesspit in Jerusalem provides window into spread of infectious diseases

A new analysis of a medieval cesspit in the Christian quarter of the old city of Jerusalem has revealed the presence of a number of ancient parasite eggs, providing a window into the nature and spread of infectious diseases in the Middle East during the 15th century.

23 Mar 2015

UConn Health cancer epidemiologist reveals effect of artificial light on health

Modern life, with its preponderance of inadequate exposure to natural light during the day and overexposure to artificial light at night, is not conducive to the body's natural sleep/wake cycle.

23 Mar 2015

Gene regulatory code remained same across the evolution

The language used in the switches that turn genes on and off has remained the same across millions of years of evolution, according to a new study led by researchers at Karolinska Institutet in Sweden. The findings, which are published in the scientific journal "eLife", indicate that the differences between animals reside in the content and length of the instructions that are written using this conserved language.

23 Mar 2015

Researchers find key step in understanding genetic mechanism of plants' environmental adaptability

A fundamental question pursued by plant scientists worldwide for the past decade has been answered by researchers led by the University of Sydney in Australia.

23 Mar 2015

Pathogen may cause high levels of virulence in closely-related hosts

When viruses such as influenza and Ebola jump from one species to another, their ability to cause harm can change dramatically, but research from the University of Cambridge shows that it may be possible to predict the virus's virulence by looking at how deadly it is in closely-related species.

23 Mar 2015

MRD-directed therapy helps boost survival of young leukemia patients

Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.

22 Mar 2015

MED15 may serve as prognostic marker for HNSCC recurrence

A new study provides the first evidence that the mediator complex subunit 15 (MED15) may play a crucial role in the pathophysiology of head and neck squamous cell carcinoma (HNSCC). MED15 overexpression was found to be associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors, according to the study published in The American Journal of Pathology.

21 Mar 2015

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases.

21 Mar 2015

Shp2 enzyme blocks protection program, boosts tumor growth

Cells have two different programs to safeguard them from getting out of control and developing cancer. One of them is senescence (biological aging). It puts cancer cells into a permanent sleep so they no longer divide and grow in an uncontrolled way.

20 Mar 2015

Mutations in hair keratins increase risk for dental defects, caries

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Olivier Duverger, National Institutes of Health-National Institute of Neurological Disorders and Stroke, Bethesda, Md., USA, will present a study titled "Hair Keratins as Structural Organic Components of Mature Enamel: The Link Between Hair Disorders and Susceptibility to Dental Caries."

20 Mar 2015

New article highlights the problem of antibiotic use in lab experiments

Scientists should reduce antibiotic use in lab experiments - according to a researcher at the University of East Anglia.

20 Mar 2015

Olive ingredients may prevent Alzheimer's disease

It has long been proven that people who follow a Mediterranean diet and keep physically and mentally active are less likely to suffer from dementia. Olives in particular appear to play a key role in this regard. But just what are the substances contained in these small, oval fruit that are so valuable? This is what a Hessen-based group of researchers from the Goethe University Frankfurt, the Technical University of Darmstadt and Darmstadt company N-Zyme BioTec GmbH intends to find out. The three-year project "NeurOliv" has a project volume of 1.3 million Euros and is funded by the Federal Ministry of Education and Research as part of the high-tech initiative "KMU-innovativ Biochance".

20 Mar 2015