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Hitchhiking of drugs on incorrect targets can cause adverse side effects

It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines.

26 Aug 2016

Kobe University researchers develop new technique for high-level genome editing operation

A team involving Kobe University researchers has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA.

26 Aug 2016

IRB Barcelona review article provides insights into emerging field of shuttle peptides

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently.

26 Aug 2016

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

More than half of children with epilepsy outgrow their seizures, yet the mechanism underlying this remission is unknown.

26 Aug 2016

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846.

26 Aug 2016

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Microglia are cells that combat various brain diseases and injuries by swallowing foreign or disruptive objects and releasing molecules that activate repair mechanisms.

26 Aug 2016

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Chromatrap is a pioneer in the development of solid-state filter-based technology that significantly enhances and accelerates the important epigenetic research tool of chromatin immunoprecipitation (ChIP).

From Chromatrap® - Porvair Sciences Ltd 26 Aug 2016

Study finds age-dependent differences in expression of allergy to dust mites

In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling.

26 Aug 2016

New report documents fetal brain abnormalities linked to congenital Zika infection

In a special report released August 23 in the journal Radiology, a team of researchers including Deborah Levine, MD, Director of Obstetric & Gynecologic ultrasound at Beth Israel Deaconess Medical Center and professor of radiology at Harvard Medical School, documented the brain abnormalities associated with congenital Zika in 45 confirmed and presumed cases from northeastern Brazil.

26 Aug 2016

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined.

26 Aug 2016

Stiff arteries can negatively impact memory and vital brain processes

As we age, our arteries gradually become less flexible, making it harder for the heart to pump blood throughout the body.

26 Aug 2016

Researchers show how cannabinoids affect vision

A multidisciplinary team including researchers from the Montreal Neurological Institute has improved our understanding of how cannabinoids, the active agent in marijuana, affect vision in vertebrates.

26 Aug 2016

Study reveals how pluripotency differs among mice, monkeys, and humans

Not too shabby, humans. New research shows that certain primate stem cells have pluripotency superior to some types derived from mice.

26 Aug 2016

Scientists isolate new multicomponent virus from mosquitoes

Scientists have identified a new "multicomponent" virus -- one containing different segments of genetic material in separate particles -- that can infect animals, according to research published today in the journal Cell Host & Microbe.

26 Aug 2016

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.

26 Aug 2016

Researchers develop new method to culture norovirus in intestinal cells

Researchers have succeeded in culturing norovirus in human intestinal cells, a breakthrough that could help scientists develop novel therapeutics and vaccines against the debilitating effects of the virus.

26 Aug 2016

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive.

26 Aug 2016

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis.

26 Aug 2016

$Developmental exposure to fracking chemicals may pose threat to fertility$

Developmental exposure to fracking chemicals may pose threat to fertility

More than 15 million Americans live within a one-mile radius of unconventional oil and gas operations. UOGs combine directional drilling and hydraulic fracturing, or "fracking," to release natural gas from underground rock.

26 Aug 2016

New camera technology paired with electron microscope allows biologists to see tiny cellular components

Using a new, lightning-fast camera paired with an electron microscope, Columbia University Medical Center scientists have captured images of one of the smallest proteins in our cells to be "seen" with a microscope.

26 Aug 2016

Medical Science News

Hitchhiking of drugs on incorrect targets can cause adverse side effects

Kobe University researchers develop new technique for high-level genome editing operation

IRB Barcelona review article provides insights into emerging field of shuttle peptides

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Study finds age-dependent differences in expression of allergy to dust mites

New report documents fetal brain abnormalities linked to congenital Zika infection

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

Stiff arteries can negatively impact memory and vital brain processes

Researchers show how cannabinoids affect vision

Study reveals how pluripotency differs among mice, monkeys, and humans

Scientists isolate new multicomponent virus from mosquitoes

New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment

Researchers develop new method to culture norovirus in intestinal cells

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Developmental exposure to fracking chemicals may pose threat to fertility

New camera technology paired with electron microscope allows biologists to see tiny cellular components

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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