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Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

Analysis of a patient's gut microbiome - the microbial population of the gastrointestinal tract - may be able to predict the likelihood of successful treatment for inflammatory bowel disease with biologic drugs that target immune system activity.

16 May 2017

IBM scientists identify new way to trigger the body's immune response to fight diseases

IBM announced its researchers have identified a new way to trigger the body's immune response by using polymer-coated graphene sheets. The research was recently published in Nature Communications.

16 May 2017

Diabetes medication could potentially help treat symptoms of Fragile X syndrome

Metformin, the most widely used drug to treat type 2 diabetes, could potentially be used to treat symptoms of Fragile X syndrome, an inherited form of intellectual disability and a cause of some forms of autism.

15 May 2017

New gene variant linked to Lou Gehrig's disease

For the first time, a variant in UBQLN4 gene has been associated with Lou Gehrig's disease or amyotrophic lateral sclerosis (ALS) - a progressive disease resulting in the loss of nerve cells that control muscle movement, which eventually leads to paralysis and death.

15 May 2017

Study provides insights into how HCMV infection causes birth defects

Fresh insights into how a common virus replicates could pave the way for new therapies to stop its spread.

15 May 2017

Research using pig knees may improve treatment of joint injuries in young people

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have published research on how the knees of pigs compare to human knees at various stages of maturity -- a finding that will advance research by this group and others on injury treatment in young people.

15 May 2017

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

University of Oregon researchers using Drosophila have identified a steroid hormone that triggers a vital transition in early brain development in which neural stem cells properly change gears to produce different kinds of neurons.

15 May 2017

Stem cell treatment helps improve motor functions, nervous system conditions in mice with ALS

Researchers at the University of South Florida show in a new study that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier.

15 May 2017

Scientists discover simple way to use light for steering killer immune cells toward tumors

The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors.

15 May 2017

Scientists uncover potential strategy to shock and kill HIV virus

Scientists at the Gladstone Institutes discovered that an enzyme called SMYD2 could be a new therapeutic target for flushing out the HIV that hides in infected individuals. Overcoming this latent virus remains the most significant obstacle to a cure.

15 May 2017

European researchers set up new network to boost use of MRI biomarkers in managing kidney disease

Researchers from 22 European countries have set up PARENCHIMA, a network that will boost the use of magnetic resonance imaging biomarkers in efficiently managing chronic kidney disease.

15 May 2017

New research could lead to earlier diagnosis and better management of inflammatory bowel disease

A University of Manchester test on the mucus lining of the intestine, performed in mice, has found changes in bacteria that could lead to inflammatory bowel disease 12 weeks earlier than previously possible through looking at stool samples, leading to the possibility of earlier diagnosis and better management of the disease in humans.

From The University of Manchester 15 May 2017

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

A new study shows cells in the initial stage of cancer change their metabolism before getting eliminated by the surrounding normal cells, providing a novel target for developing cancer prevention drugs.

15 May 2017

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Osaka University-led researchers identified differences in how three drugs bind to tumor necrosis factor, a key mediator of inflammatory disease. The team used sedimentation velocity analytical ultracentrifugation to investigate drug-target binding in a physiological environment and at clinically-relevant concentrations.

15 May 2017

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

A new study shows that whole tomato extracts from two different Southern Italy cultivars inhibit gastric cancer cell growth and malignant features, paving the way for future studies aimed at implementing lifestyle habits not only for prevention but potentially as a support to conventional therapies.

15 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Scientists discover potential brain imaging predictor for early dementia

University of Toronto and Baycrest Rotman Research Institute (RRI) scientists have discovered a potential brain imaging predictor for dementia, which illustrates that changes to the brain's structure may occur years prior to a diagnosis, even before individuals notice their own memory problems.

12 May 2017

Novel method helps create anticancer nanoclusters without use of additional chemicals

Researchers at Aalto University, Finland, have developed anticancer nanomaterials by simulating the volcano-induced dynamic chemistry of the deep ocean.

12 May 2017

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Scientists develop new method to clear antibiotic-resistant bacteria from the eyes

Scientists have developed a new method to clear antibiotic resistant bacteria from the surface of the eye – introducing a new strain of bacteria that preys on other microorganisms.

12 May 2017

Medical Science News

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

IBM scientists identify new way to trigger the body's immune response to fight diseases

Diabetes medication could potentially help treat symptoms of Fragile X syndrome

New gene variant linked to Lou Gehrig's disease

Study provides insights into how HCMV infection causes birth defects

Research using pig knees may improve treatment of joint injuries in young people

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

Stem cell treatment helps improve motor functions, nervous system conditions in mice with ALS

Scientists discover simple way to use light for steering killer immune cells toward tumors

Scientists uncover potential strategy to shock and kill HIV virus

European researchers set up new network to boost use of MRI biomarkers in managing kidney disease

New research could lead to earlier diagnosis and better management of inflammatory bowel disease

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

Research findings provide insight into mechanisms underlying differences in efficacy of anti-TNF drugs

Study prompts further assessment of tomato extracts’ use in gastric cancer prevention

Study findings could pave way for better drugs to fight against parasitic infections

Scientists discover potential brain imaging predictor for early dementia

Novel method helps create anticancer nanoclusters without use of additional chemicals

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Scientists develop new method to clear antibiotic-resistant bacteria from the eyes

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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