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Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

The bacteria that live in dental plaque and contribute to tooth decay often resist traditional antimicrobial treatment, as they can "hide" within a sticky biofilm matrix, a glue-like polymer scaffold.

26 Jul 2016

Stereotactic radiosurgery could be more effective for patients with few metastatic brain tumors

Patients with three or fewer metastatic brain tumors who received treatment with stereotactic radiosurgery (SRS) had less cognitive deterioration three months after treatment than patients who received SRS combined with whole brain radiation therapy (WBRT).

26 Jul 2016

Researchers discover three new risk genes for ALS

Published today in Nature Genetics, the study reveals three new risk genes for ALS and one of these - C21orf2 - increases an individual's risk of developing the dis-ease by 65 per cent.

26 Jul 2016

Scientists clarify mechanism of defective immune defense in G6PD patients

Favism is a common hereditary disease, affecting around 400 million people worldwide. It is caused by a lack of the enzyme glucose-6-phosphate dehydrogenase (G6PD).

26 Jul 2016

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial, making it one of the most common genetic causes of the disease, according to a paper published in Nature Genetics.

26 Jul 2016

Novel community-produced biological network models hold potential in drug discovery and toxicology

A new set of community-produced biological network models has been shown to allow a deeper understanding of the mechanisms underlying a range of diseases.

26 Jul 2016

Odor identification test may help detect early-stage Alzheimer's disease

Researchers from Columbia University Medical Center, New York State Psychiatric Institute, and NewYork-Presbyterian reported that an odor identification test may prove useful in predicting cognitive decline and detecting early-stage Alzheimer's disease.

26 Jul 2016

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Three manuscripts published in the recent issue of the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer, explored the versatility of liquid biopsies by identifying EGFR mutations using circulating tumor DNA (ctDNA) in urine and plasma and examining circulating tumor cells (CTCs) in plasma to predict the risk of lung cancer recurrence after surgical resection.

26 Jul 2016

Researchers identify genetic variants linked to radiotherapy side-effects in prostate cancer patients

A new study involving researchers from The University of Manchester looked at the genetic information of more than 1,500 prostate cancer patients and identified two variants linked to increased risk of radiotherapy side-effects.

26 Jul 2016

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

Three key factors increase the risk for patient-to-patient transmission of an extremely drug-resistant bacteria known as CP-CRE, according to a new study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

26 Jul 2016

New research could provide insights into Alzheimer's and schizophrenia

Researchers comparing mouse and macaque brains have found evidence of an evolutionary universal brain structure in mammals that enables comparisons of cortical networks between species.

26 Jul 2016

Scientists unveil structure of Zika NS1 protein

Researchers have revealed the molecular structure of a protein produced by the Zika virus that is thought to be involved in the virus's reproduction and its interaction with a host's immune system.

26 Jul 2016

Embryonic stem cell gene Nanog holds potential for reversing effects of aging

The fountain of youth may reside in an embryonic stem cell gene named Nanog.

26 Jul 2016

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme.

26 Jul 2016

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Every five minutes someone in the U.S. dies from a blood clot, through its role in strokes, heart attacks or other severe conditions.

26 Jul 2016

Common drug for type 2 diabetes may play surprising role in preventing preterm birth

Metformin, a medication routinely used by millions of people with type 2 diabetes, may also play an unexpected role in blocking a significant cause of preterm birth, according to research findings published July 25.

26 Jul 2016

Adding DNA sequencing to newborn screenings may increase early diagnosis of cystic fibrosis

A study by researchers at Children's Hospital Los Angeles, Brigham and Women's Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive additional screening in order to better predict the risk of developing CF later in life.

26 Jul 2016

Menopause and insomnia could make women age faster

Two UCLA studies reveal that menopause--and the insomnia that often accompanies it -- make women age faster.

26 Jul 2016

New study uncovers way to characterize black box of malignant melanoma

When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions of metastatic cells with the brain microenvironment remain shrouded in mystery.

26 Jul 2016

Study reveals unexpected process for acquiring chemoresistance in breast cancers

A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.

25 Jul 2016

Medical Science News

Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

Stereotactic radiosurgery could be more effective for patients with few metastatic brain tumors

Researchers discover three new risk genes for ALS

Scientists clarify mechanism of defective immune defense in G6PD patients

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Novel community-produced biological network models hold potential in drug discovery and toxicology

Odor identification test may help detect early-stage Alzheimer's disease

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Researchers identify genetic variants linked to radiotherapy side-effects in prostate cancer patients

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

New research could provide insights into Alzheimer's and schizophrenia

Scientists unveil structure of Zika NS1 protein

Embryonic stem cell gene Nanog holds potential for reversing effects of aging

Male hormones can reverse biological drivers of aging, study shows

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Common drug for type 2 diabetes may play surprising role in preventing preterm birth

Adding DNA sequencing to newborn screenings may increase early diagnosis of cystic fibrosis

Menopause and insomnia could make women age faster

New study uncovers way to characterize black box of malignant melanoma

Study reveals unexpected process for acquiring chemoresistance in breast cancers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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