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Data provides better understanding of genetic activity during lung cancer development

Scientists at the University of Granada, incollaboration with the universities of Harvard and Yale (United States) have provided new data for a better understanding of the alterations produced during the development of lung cancer, the tumour with the highest yearly death rate in Spain.

3 Mar 2015

Sall4 protein helps fix DNA damage

A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a similar role in cancer cells, helping them fix DNA damage to survive chemotherapy.

3 Mar 2015

Toning down TREM2 receptor's activity may help prevent neurodegeneration in AD patients

Tackling brain inflammation ameliorates Alzheimer's disease (AD), according to a study published in The Journal of Experimental Medicine.

3 Mar 2015

Higher intake of lycopene may lower risk of renal cell carcinoma in postmenopausal women

A higher intake by postmenopausal women of the natural antioxidant lycopene, found in foods like tomatoes, watermelon and papaya, may lower the risk of renal cell carcinoma, a type of kidney cancer.

2 Mar 2015

New genetic discovery may lead to effective treatments for Huntington's disease

A new genetic discovery in the field of Huntington's disease (HD) could mean a more effective way in determining severity of this neurological disease when using specific treatments. This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease.

2 Mar 2015

People with diabetes more prone to depression, anxiety

People with diabetes are more prone to anxiety and depression than those with other chronic diseases that require similar levels of management. The reasons for this aren't well understood, but Joslin Diabetes Center researchers have discovered one potential explanation.

2 Mar 2015

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

Chemists at Bielefeld University have developed a molecule containing copper that binds specifically with DNA and prevents the spread of cancer. First results show that it kills the cancer cells more quickly than cisplatin - a widely used anti-cancer drug that is frequently administered in chemotherapy.

2 Mar 2015

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.

2 Mar 2015

Minihepcidin reverses iron overload of hemochromatosis, stops susceptibility to infections

Hemochromatosis (HH) is the most common genetic disorder in the western world, and yet is barely known. Only in the US 1 in 9 people carry the mutation (although not necessarily the disease).

2 Mar 2015

Study details a new pathway for tumor formation

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine (SVM) have identified the biological mechanism that may give some cancer cells the ability to form tumors in dogs.

2 Mar 2015

Culture conditions in which stem cells are grown can affect genetic stability

The therapeutic promise of human stem cells is indisputably huge, but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities.

28 Feb 2015

Researchers solve secret of mysterious reverse-wired eyeball

From a practical standpoint, the wiring of the human eye - a product of our evolutionary baggage - doesn't make a lot of sense. In vertebrates, photoreceptors are located behind the neurons in the back of the eye - resulting in light scattering by the nervous fibers and blurring of our vision.

28 Feb 2015

New book provides in-depth, advanced understanding of Ebola and rabies viruses

Significant human and animal pathogens remain major scourges to human health. Recent devastating Ebola virus disease outbreak in West Africa underscores the importance of understanding the biology of replication and response of host cells to infection by these pathogens.

28 Feb 2015

Genetic decanalization can lead to complex genetic diseases in humans

The information encoded in the DNA of an organism is not sufficient to determine the expression pattern of genes. This fact has been known even before the discovery of epigenetics, which refers to external modifications to the DNA that turn genes "on" or "off".

28 Feb 2015

Early intervention with GLP-1 analogues may delay onset of type 2 diabetes

GLP-1 is a hormone that regulates glucose levels in the body by stimulating the secretion of insulin, and GLP-1 also inhibits appetite. "We have found that GLP-1 is reduced by up to 25% among people with pre-diabetes and up to 20% among obese people compared to normal weight people.

28 Feb 2015

Researchers successfully convert adult human skin cells into neurons that control appetite

Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight control and testing new therapies for obesity.

28 Feb 2015

Drosophila Research Conference to highlight recent advances in genetics research

Over 1,500 scientists from 30 countries and 46 states will attend next week's 56th Annual Drosophila Research Conference organized by the Genetics Society of America, March 4–8 in Chicago, IL.

28 Feb 2015

New strategy may ensure safety of adult epidermal stem cells before performing treatments

A team of European researchers has devised a strategy to ensure that adult epidermal stem cells are safe before they are used as treatments for patients. The approach involves a clonal strategy where stem cells are collected and cultivated, genetically modified and single cells isolated before being rigorously tested to make sure they meet the highest possible safety criteria.

28 Feb 2015

Neuroprotective compounds can limit damage to the brain during ischemic stroke

In the 1990s, neuroscientists identified a class of drugs that showed promise in the area of stroke. NMDA receptor antagonists could limit damage to the brain in animal models of stroke. But one problem complicated testing the drugs in a clinical setting: the side effects included disorientation and hallucinations.

28 Feb 2015

New technology could help researchers advance blood biomarker capabilities for TBI

New technology being introduced at NYU Langone Medical Center could help researchers advance blood biomarker capabilities that show changes in low concentrations of specific proteins present following a neurological injury.

28 Feb 2015

Medical Science News

Data provides better understanding of genetic activity during lung cancer development

Sall4 protein helps fix DNA damage

Toning down TREM2 receptor's activity may help prevent neurodegeneration in AD patients

Higher intake of lycopene may lower risk of renal cell carcinoma in postmenopausal women

New genetic discovery may lead to effective treatments for Huntington's disease

People with diabetes more prone to depression, anxiety

Bielefeld University chemists develop copper molecule that could help prevent spread of cancer

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

Minihepcidin reverses iron overload of hemochromatosis, stops susceptibility to infections

Study details a new pathway for tumor formation

Culture conditions in which stem cells are grown can affect genetic stability

Researchers solve secret of mysterious reverse-wired eyeball

New book provides in-depth, advanced understanding of Ebola and rabies viruses

Genetic decanalization can lead to complex genetic diseases in humans

Early intervention with GLP-1 analogues may delay onset of type 2 diabetes

Researchers successfully convert adult human skin cells into neurons that control appetite

Drosophila Research Conference to highlight recent advances in genetics research

New strategy may ensure safety of adult epidermal stem cells before performing treatments

Neuroprotective compounds can limit damage to the brain during ischemic stroke

New technology could help researchers advance blood biomarker capabilities for TBI

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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