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New Duke-NUS-led study identifies super-potent antibody that can neutralize dengue virus

A new Duke-NUS-led study has identified a super-potent antibody which requires a minute amount to neutralize the dengue virus.

21 Feb 2015

Mayo Clinic researchers identify molecule that lays groundwork for development of pancreatic cancer

A research team led by investigators from Mayo Clinic's campus in Jacksonville, Florida, and the University of Oslo, Norway, have identified a molecule that pushes normal pancreatic cells to transform their shape, laying the groundwork for development of pancreatic cancer -- one of the most difficult tumors to treat.

21 Feb 2015

Discovery could help scientists treat heart problems

The average heart beats 35 million times a year - 2.5 billion times over a lifetime. Those beats must be precisely calibrated; even a small divergence from the metronomic rhythm can cause sudden death. For decades, scientists have wondered exactly how the heart stays so precisely on rhythm even though it contains so many moving parts.

21 Feb 2015

Betaretrovirus may infect patients with primary biliary cirrhosis

In a new study published in Alimentary Pharmacology & Therapeutics, researchers at the University of Alberta's Faculty of Medicine & Dentistry have shown that a betaretrovirus which resembles a mouse mammary tumor virus infects patients with the rare liver disease, primary biliary cirrhosis (PBC).

20 Feb 2015

Proximity Ligation Assay helps detect effectiveness of cancer vaccines

Cancer vaccines are designed to turn the body's own immune system specifically against tumor cells. Particularly promising are vaccines that are directed against so-called neoantigens: These are proteins that have undergone a genetic mutation in tumor cells and, therefore, differ from their counterparts in healthy cells.

20 Feb 2015

Researchers develop durable antibacterial coatings of nanocomposites

Ruthless with bacteria, harmless to human cells. New, durable antibacterial coatings of nanocomposites, developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, will in future help to improve the hygiene of sportswear, and used in medicine, will reduce the rate of infections and shorten the times of in-patient hospital admissions.

20 Feb 2015

Epigenome-wide association study helps discover genes linked to allergies and asthma

Researchers from Canada, the UK, Sweden and the US have discovered more than 30 genes that strongly affect an antibody involved in allergies and asthma. Some of the genes could provide targets for drugs to treat those conditions, according to the international team's study, published online in Nature on Feb. 18.

20 Feb 2015

Industrial Biotechnology presents insights on cellulose nanocrystal toxicity

Novel nanomaterials derived from cellulose have many promising industrial applications, are biobased and biodegradable, and can be produced at relatively low cost. Their potential toxicity--whether ingested, inhaled, on contact with the skin, or on exposure to cells within the body--is a topic of intense discussion, and the latest evidence and insights on cellulose nanocrystal toxicity are presented in a Review article in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

20 Feb 2015

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

23andMe, Inc., the leading personal genetics company, today announced that it has been granted authority by the U.S. Food and Drug Administration (FDA) to market the first direct-to-consumer genetic test under a regulatory classification for novel devices.

20 Feb 2015

Philadelphia College of Osteopathic Medicine professor explores causes, treatments of anorexia

Eating disorders are serious, debilitating conditions associated with significant morbidity and mortality, and distress. Anorexia nervosa, in particular, is associated with the highest mortality and suicide rates; compared to healthy peers, women with anorexia are up to 12 times more likely to die of any cause, and approximately 57 times more likely to die from suicide, over the same period of time.

20 Feb 2015

New partnership aims to create stem cell resource to study psychiatric disorders

The New York Stem Cell Foundation and the Stanley Center at the Broad Institute of MIT and Harvard are partnering to create a foundational stem cell resource to study psychiatric disorders through the production of induced pluripotent stem (iPS) cell lines from individuals with schizophrenia and other psychiatric disorders.

20 Feb 2015

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

Jason Meyer, Ph.D., assistant professor of biology in the School of Science at Indiana University-Purdue University Indianapolis, has received a National Institutes of Health grant to study how glaucoma develops in stem cells created from skin cells genetically predisposed to the disease.

20 Feb 2015

New research finds that synthetic flame retardants can cause metabolic and liver problems

Chemicals used as synthetic flame retardants that are found in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems that can lead to insulin resistance, which is a major cause of obesity, according to new research from the University of New Hampshire.

20 Feb 2015

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

This is the story of Abl and Src -- two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.

20 Feb 2015

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs.

20 Feb 2015

Scientists identify promising new therapeutic target for prostate cancer

Keck Medicine of the University of Southern California scientists have found a promising new therapeutic target for prostate cancer. The findings offer evidence that a newly discovered member of a family of cell surface proteins called G-protein coupled receptors (GPCRs) promotes prostate cancer cell growth. The protein, GPR158, was found while the researchers were looking for new drug targets for glaucoma.

20 Feb 2015

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Free-standing nanoparticle films are of great interest for technical applications, such as the development of nanoelectronic devices. In the journal Angewandte Chemie, Korean scientists have introduced very flexible and stable monolayers of gold nanoparticles made by a self-assembly process based on protein aggregation. The films were used to coat wafers up to 10 cm in diameter.

20 Feb 2015

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

Tumors require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach when combined with vascular growth factors responsible for cell death.

19 Feb 2015

Study helps solve mystery about how genetic variations can increase cancer risk

Single-letter genetic variations within parts of the genome once dismissed as 'junk DNA' can increase cancer risk through wormhole-like effects on far-off genes, new research shows.

19 Feb 2015

Medical Science News

New Duke-NUS-led study identifies super-potent antibody that can neutralize dengue virus

Mayo Clinic researchers identify molecule that lays groundwork for development of pancreatic cancer

Discovery could help scientists treat heart problems

Betaretrovirus may infect patients with primary biliary cirrhosis

Proximity Ligation Assay helps detect effectiveness of cancer vaccines

Researchers develop durable antibacterial coatings of nanocomposites

Epigenome-wide association study helps discover genes linked to allergies and asthma

Industrial Biotechnology presents insights on cellulose nanocrystal toxicity

23andMe granted FDA approval to market direct-to-consumer genetic test under novel device classification

Philadelphia College of Osteopathic Medicine professor explores causes, treatments of anorexia

New partnership aims to create stem cell resource to study psychiatric disorders

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

IUPUI's Jason Meyer awarded $1.8 million NIH grant to explore how glaucoma develops in stem cells

New research finds that synthetic flame retardants can cause metabolic and liver problems

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists identify promising new therapeutic target for prostate cancer

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

Study helps solve mystery about how genetic variations can increase cancer risk

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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