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'Turbocharged' protein holds promise in hemophilia gene therapy

Using gene therapy to produce a mutant human protein with unusually high blood-clotting power, scientists have successfully treated dogs with the bleeding disorder hemophilia, without triggering an unwanted immune response.

13 Mar 2015

Study describes the dual role of microRNA during hepatitis C infection

In the battle between a cell and a virus, either side may resort to subterfuge. Molecular messages, which control the cellular machinery both sides need, are vulnerable to interception or forgery.

13 Mar 2015

Researchers develop 'warhead' molecule that targets deadly bacteria, spares healthy cells

Targeting deadly, drug-resistant bacteria poses a serious challenge to researchers looking for antibiotics that can kill pathogens without causing collateral damage in human cells.

13 Mar 2015

New database on healthy immune system may help design future studies on autoimmune disorders

An extensive database identifying immune traits, such as how immune cell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal Cell.

13 Mar 2015

Study suggests distinct role of brain regions in dental pain relief

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Michael L. Meier, Center for Dental Medicine, University of Zürich, Switzerland, will present a study titled "Distinct Brain Mechanisms Related to Dental Pain Relief."

13 Mar 2015

Glyconanoparticles may help reduce cell damage and inflammation after stroke

Materials resulting from chemical bonding of glucosamine, a type of sugar, with fullerenes, kind of nanoparticles known as buckyballs, might help to reduce cell damage and inflammation occurring after stroke.

13 Mar 2015

Cancer drug promotes neuronal regeneration after spinal cord injury

Damage to the spinal cord rarely heals because the injured nerve cells fail to regenerate. The regrowth of their long nerve fibers is hindered by scar tissue and molecular processes inside the nerves.

13 Mar 2015

Scientists explore the potential genetic basis for loneliness

Loneliness may be a fundamental part of the human condition, but scientists have only recently begun exploring its causes, consequences, and potential interventions.

13 Mar 2015

When you eat is just as important as what you eat

If you're looking to improve your heart health by changing your diet, when you eat may be just as important as what you eat.

13 Mar 2015

High levels of triglycerides, cholesterol can keep vitamin E tied up in blood stream

In the continuing debate over how much vitamin E is enough, a new study has found that high levels of blood lipids such as cholesterol and triglycerides can keep this essential micronutrient tied up in the blood stream, and prevent vitamin E from reaching the tissues that need it.

13 Mar 2015

Gene variant may help predict people’s response to investigational Alzheimer's therapy

Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease (AD).

13 Mar 2015

Researchers discover gene associated with congenital anomaly of urinary tract

An interdisciplinary team of researchers under the direction of the University of Bonn Hospital have discovered a gene which is associated with a rare congenital anomaly of the urinary tract called classic bladder exstrophy.

13 Mar 2015

Scientists simplify chemical synthesis of small molecules using 3D printing technology

Howard Hughes Medical Institute scientists have simplified the chemical synthesis of small molecules, eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine and technology.

13 Mar 2015

Study: New gene therapy safe, effective for patients with hemophilia B

A multi-year, ongoing study suggests that a new kind of gene therapy for hemophilia B could be safe and effective for human patients. Published in the journal Science Translational Medicine, the research showed that a reprogrammed retrovirus could successfully transfer new factor IX (clotting) genes into animals with hemophilia B to dramatically decrease spontaneous bleeding.

12 Mar 2015

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

For infants with severe combined immunodeficiency (SCID), something as simple as a common cold or ear infection can be fatal. Born with an incomplete immune system, kids who have SCID--also known as "bubble boy" or "bubble baby" disease--can't fight off even the mildest of germs.

12 Mar 2015

Penn researcher named a recipient of 2015 Paul Ehrlich and Ludwig Darmstaedter Prize

University of Pennsylvania cancer and HIV expert Carl June, MD, has been named one of two recipients of the 2015 Paul Ehrlich and Ludwig Darmstaedter Prize for his outstanding work in cancer immunotherapy. Since 1952, the Paul Ehrlich and Ludwig Darmstaedter Prize has been awarded to scientists who have made great advancements in the fields in which Paul Ehrlich worked, in particular immunology, cancer research, microbiology, and chemotherapy.

12 Mar 2015

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Melbourne researchers have developed a new genome editing technology that can target and kill blood cancer cells with high accuracy.

12 Mar 2015

Slow-growing tumors have treatment-resistant stem cells, shows study

Scientists are eager to make use of stem cells' extraordinary power to transform into nearly any kind of cell, but that ability also is cause for concern in cancer treatment.

12 Mar 2015

McGill researchers identify key mechanism by which environmental factors influence traits

Until now scientists have believed that the variations in traits such as our height, skin colour, tendency to gain weight or not, intelligence, tendency to develop certain diseases, etc., all of them traits that exist along a continuum, were a result of both genetic and environmental factors. But they didn't know how exactly these things worked together.

12 Mar 2015

Medicine-loaded nanoparticles could help patients achieve corneal transplant success

There are about 48,000 corneal transplants done each year in the U.S., compared to approximately 16,000 kidney transplants and 2,100 heart transplants. Out of the 48,000 corneal transplants done, 10 percent of them end up in rejection, largely due to poor medication compliance. This costs the health care system and puts undue strain on clinicians, patients and their families.

12 Mar 2015

Medical Science News

'Turbocharged' protein holds promise in hemophilia gene therapy

Study describes the dual role of microRNA during hepatitis C infection

Researchers develop 'warhead' molecule that targets deadly bacteria, spares healthy cells

New database on healthy immune system may help design future studies on autoimmune disorders

Study suggests distinct role of brain regions in dental pain relief

Glyconanoparticles may help reduce cell damage and inflammation after stroke

Cancer drug promotes neuronal regeneration after spinal cord injury

Scientists explore the potential genetic basis for loneliness

When you eat is just as important as what you eat

High levels of triglycerides, cholesterol can keep vitamin E tied up in blood stream

Gene variant may help predict people’s response to investigational Alzheimer's therapy

Researchers discover gene associated with congenital anomaly of urinary tract

Scientists simplify chemical synthesis of small molecules using 3D printing technology

Study: New gene therapy safe, effective for patients with hemophilia B

Finding could lead to more effective, less invasive treatment for 'bubble boy' disease

Penn researcher named a recipient of 2015 Paul Ehrlich and Ludwig Darmstaedter Prize

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Slow-growing tumors have treatment-resistant stem cells, shows study

McGill researchers identify key mechanism by which environmental factors influence traits

Medicine-loaded nanoparticles could help patients achieve corneal transplant success

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