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Japanese researchers identify mechanism for hormone that limits liver fibrosis

Nonalcoholic steatohepatitis (NASH) has been emerging worldwide and effective treatment, especially for liver fibrosis, is essential for improving the prognosis.

13 Oct 2016

New poster presented at RCGP annual conference highlights dangers of hyperpolypharmacy

A poster at last week’s RCGP annual conference highlighted the danger of hyperpolypharmacy, the use of ten or more medications, in the population aged over 75.

13 Oct 2016

URMC scientists receive award to explore new treatments for Huntington's disease

A new award from the CHDI Foundation will advance promising research that aims to slow the progression of Huntington's disease.

13 Oct 2016

New research reveals key protein involved in heart failure

A key protein that causes heart failure has been revealed through new research from a collaboration based in Kumamoto University, Japan.

13 Oct 2016

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

A multi-center team of researchers are planning a clinical trial using cardiosphere-derived cells (CDCs) (a heterogeneous cluster of proliferating cardiac cells that include mesenchymal stem cells) to regenerate the tissue and improve function of the heart in patients who have suffered heart attacks (myocardial infarction, MI).

13 Oct 2016

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

In a study using Real-time intraoperative magnetic resonance imaging (RT-IMRI) to guide the transplantation of induced pluripotent stem cell (iPSC)-derived neurons into the brains of non-human primates modeled with Parkinson's disease, researchers found that RT-IMRI guidance not only allows for better visualization and monitoring of the procedure, but also helps cell survival.

13 Oct 2016

IIVS releases technical training video on non-animal testing methods in laboratories

Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing, the Institute for In Vitro Sciences, Inc. has released a technical training video that describes a cell-based in vitro method for assessing phototoxicity - the potential for chemicals to cause damage after being exposed to light.

13 Oct 2016

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

About 15 percent of the 10-12 million people in the U.S. with hypothyroidism, or an underactive thyroid, continue to feel sick despite following the standard of care recommended by the American Thyroid Association.

13 Oct 2016

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

The advanced phase of acute kidney injury can be fatal in even one in two patients. Fortunately, now it will be possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis good.

13 Oct 2016

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Consuming too much folate (vitamin B9) is associated with increased risk for a nerve-damage disorder in older adults who have a common genetic variant.

12 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's

Alzheimer's and Parkinson's diseases are different neurodegenerative conditions that can sometimes affect the same person, which has led scientists to investigate possible links between the two.

12 Oct 2016

Research findings raise hope for better treatment of diabetic wounds

Diabetics often have to contend with wounds that heal poorly. Researchers at the Max Planck Institute for Biology of Ageing, the CECAD Excellence Cluster and the Institute of Genetics of the University of Cologne have now gained fresh insights into the underlying cellular mechanisms.

12 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Fetal brains use unique amplifier to transmit signals, research shows

Fetal brains use a special amplifier in order to transmit signals, according to research published in the journal eLife by George Washington University's (GW) Matthew Colonnese, Ph.D. and Yasunobu Murata, Ph.D. Early neural connections are sparse, weak, and unreliable.

12 Oct 2016

Study on common bacterium presents new pathway to combat gastric cancers

A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study led by University of Georgia researchers.

12 Oct 2016

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments.

12 Oct 2016

Researchers uncover how vitamins A and C act to modify epigenetic cell memory

Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic 'memory' held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one identity to another.

12 Oct 2016

Measuring the activity of a mouse brain from a single snapshot

Drs Nicolas Renier and Zhuhao Wu are post-doctoral fellows in the laboratory of Marc Tessier-Lavigne, Carson Family Professor and head of the Laboratory of Brain Development and Repair and President of Rockefeller University in New York. Over recent years, they have co-developed methodologies for new imaging techniques applying light sheet microscopy. Their latest work shows the study of neuronal activity in intact brains.

12 Oct 2016

High-protein diet eliminates metabolic benefits of weight loss in obese women

Dieters sometimes consume extra protein to stave off hunger and prevent loss of muscle tissue that often comes with weight loss.

12 Oct 2016

Medical Science News

Japanese researchers identify mechanism for hormone that limits liver fibrosis

New poster presented at RCGP annual conference highlights dangers of hyperpolypharmacy

URMC scientists receive award to explore new treatments for Huntington's disease

New research reveals key protein involved in heart failure

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

IIVS releases technical training video on non-animal testing methods in laboratories

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's

Research findings raise hope for better treatment of diabetic wounds

Study identifies mechanistic link between maternal obesity and childhood hypertension

Fetal brains use unique amplifier to transmit signals, research shows

Study on common bacterium presents new pathway to combat gastric cancers

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

Researchers uncover how vitamins A and C act to modify epigenetic cell memory

Measuring the activity of a mouse brain from a single snapshot

High-protein diet eliminates metabolic benefits of weight loss in obese women

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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