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Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline.

25 May 2016

Creating reference standards for cannabis testing: an interview with Adam Ross

The main applications for cannabis testing is to ensure that the product produced, whether the flower itself, tinctures, edibles, etc. contain acceptable levels of approved pesticide or other residues leftover from the growing or processing process.

25 May 2016

Alcohol exposure during early to mid-adolescence linked to chronic stress vulnerability

Drinking during early to mid-adolescence can lead to vulnerability to chronic stress, according to new research from Binghamton University, State University of New York.

25 May 2016

Single enzyme doing the work of a trio could offer precise way to treat diseases

Researchers identified a single enzyme doing the work of a trio thought necessary to control a common cellular signaling process being pursued as a therapeutic target.

24 May 2016

New computational model simulates how neurons in visual cortex process sensory stimuli

At any given moment, the neuronal circuits in the brain receive and process sensory information that permits us to perceive and interact with the environment. Yet it remains unclear how the visual brain processes natural stimuli.

24 May 2016

Early epigenetic changes could open way for new preventative strategies for ovarian cancer

Research revealing early changes at epigenetic level points to possible new prevention strategies for ovarian cancer. The discovery of early changes in the cells of the Fallopian tubes of women carrying the BRCA genetic mutation could open the way for new preventative strategies for ovarian cancer, reducing the need for invasive surgery, according to research published today in science journal Nature Communications.

24 May 2016

ANK3 and other genes may play key role in affecting mood, stress and longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research.

24 May 2016

Researchers discover new potential treatment target for liver cancer

Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.

24 May 2016

Scientists study how viral evolution occurs

Viruses evolve quickly. A small tweak to the genetic makeup of a mostly mild strain of influenza can give rise to the next pandemic. An equally small change to the same strain in a different setting can fade it into obscurity.

24 May 2016

National Cancer Moonshot initiative needs to target proteins that drive cancer

The National Cancer Moonshot initiative needs to move beyond genomics to target the proteins that are driving cancer, according to an Inova Health System and George Mason University collaborative paper published Thursday in the American Association for Cancer Research.

24 May 2016

Chloride switch controls critical step in basement membrane formation

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

24 May 2016

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."

24 May 2016

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine revealed that triple-negative breast cancer (TNBC), which has generally been unresponsive to hormone receptor-targeted treatments, can indeed be treated using vitamin D and androgen receptor-targeted therapy.

24 May 2016

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Using a miniature microscope that opens a window into the brain, UCLA neuroscientists have identified in mice how the brain links different memories over time. While aging weakens these connections, the team devised a way for the middle-aged brain to reconnect separate memories.

24 May 2016

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.

24 May 2016

Researchers find genetic mutations linked to increased risk factor for PTSD

In the largest study of DNA samples from service members with Post-Traumatic Stress Disorder (PTSD), researchers have identified genetic mutations that may be associated with an increased risk factor for PTSD.

24 May 2016

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women.

24 May 2016

Breakthrough study observes structural changes in carbonic anhydrase for first time

A new study by an international team of researchers, affiliated with Ulsan National Institute of Science and Technology has announced that they have succeeded for the first time in observing the structural changes in carbonic anhydrase.

24 May 2016

Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Rare mutation may reduce risk of developing arteriosclerosis by 34%

According to new international research, just less than one per cent of the population is naturally protected against developing chronic coronary artery diseases.

24 May 2016

Medical Science News

Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Creating reference standards for cannabis testing: an interview with Adam Ross

Alcohol exposure during early to mid-adolescence linked to chronic stress vulnerability

Single enzyme doing the work of a trio could offer precise way to treat diseases

New computational model simulates how neurons in visual cortex process sensory stimuli

Early epigenetic changes could open way for new preventative strategies for ovarian cancer

ANK3 and other genes may play key role in affecting mood, stress and longevity

Researchers discover new potential treatment target for liver cancer

Scientists study how viral evolution occurs

National Cancer Moonshot initiative needs to target proteins that drive cancer

Chloride switch controls critical step in basement membrane formation

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Vitamin D and androgen receptor-targeted therapy may help treat TNBC

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Researchers find genetic mutations linked to increased risk factor for PTSD

BUSM researchers uncover genetic, epigenetic alteration overlaps in breast and ovarian cancer

Breakthrough study observes structural changes in carbonic anhydrase for first time

Personalized DXM-loaded leukosomes may help treat inflammation

Rare mutation may reduce risk of developing arteriosclerosis by 34%

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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