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Study identifies H3.3 protein as key regulator in cellular senescence

Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published online this month in the journal Nature Communications.

23 Nov 2014

Next-generation biomarker detects tumour cells, delivers anti-cancer drugs

Nanyang Technological University in Singapore has invented a unique biomarker with two exceptional functions.

23 Nov 2014

Researchers discover why only some patients respond to ipilimumab drug

A collaborative team of leaders in the field of cancer immunology from Memorial Sloan Kettering Cancer Center has made a key discovery that advances the understanding of why some patients respond to ipilimumab, an immunotherapy drug, while others do not. MSK was at the forefront of the clinical research that brought this CTLA-4 blocking antibody to melanoma patients.

23 Nov 2014

Research paves way for improving efficacy of ALS treatement

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that primarily kills motor neurons, leading to paralysis and death 2 to 5 years from diagnosis. Currently ALS has no cure. Despite promising early-stage research, the majority of drugs in development for ALS have failed. Now researchers have uncovered a possible explanation.

23 Nov 2014

Unique ability helps prolific bacterium to afflict humans, animals and even plants

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism -- a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

23 Nov 2014

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

In a new study conducted by the Sagol Department of Neurobiology at the University of Haifa and published recently in the Journal of Neuroscience, researchers report that they've found a way to improve memory by manipulating a specific molecule that is known to function poorly in old age and is closely linked to Alzheimer's disease.

23 Nov 2014

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

New evidence that immune checkpoint inhibitors may work in glioblastoma and brain metastases was presented today by Dr Anna Sophie Berghoff at the ESMO Symposium on Immuno-Oncology 2014 in Geneva, Switzerland.

23 Nov 2014

UCLA creates largest-ever protein that self-assembles into molecular 'cage'

UCLA biochemists have created the largest-ever protein that self-assembles into a molecular "cage." The research could lead to synthetic vaccines that protect people from the flu, HIV and other diseases.

23 Nov 2014

Researchers examine genomic landscapes of humans and mice

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

23 Nov 2014

Exposure to peanut proteins in household dust may trigger peanut allergy

Exposure to peanut proteins in household dust may be a trigger of peanut allergy, according to a study published today in the Journal of Allergy and Clinical Immunology.

23 Nov 2014

Scientists identify four new genes associated with severe food allergy

Scientists have identified four new genes associated with the severe food allergy eosinophilic esophagitis (EoE). Because the genes appear to have roles in other allergic diseases and in inflammation, the findings may point toward potential new treatments for EoE.

21 Nov 2014

TSRI study shows how mutations in Tmie gene can cause deafness from birth

Scientists at The Scripps Research Institute have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies.

21 Nov 2014

Researchers discover new method to deliver drugs into aggressive tumors

A multi-disciplinary team of Yale Cancer Center researchers has discovered a promising new method for delivering drugs into aggressive tumors by exploiting a unique feature of tumors themselves.

21 Nov 2014

MD Anderson study sheds light on little-known protein complex

A study at The University of Texas MD Anderson Cancer Center led by Mong-Hong Lee, Ph.D., a professor of molecular and cellular oncology, has demonstrated the significance of CSN6 in regulating Myc which may very well open up a new pathway for treating and killing tumors.

21 Nov 2014

MGH investigators develop system to accurately track the process of falling asleep

Massachusetts General Hospital investigators have developed a system to accurately track the dynamic process of falling asleep, something has not been possible with existing techniques. In their report in the October issue of the open-access journal PLOS Computational Biology, the research team describes how combining key physiologic measurements with a behavioral task that does not interfere with sleep onset gives a better picture of the gradual process of falling asleep.

21 Nov 2014

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges.

21 Nov 2014

Researchers discover a new way to combat influenza virus infection

The influenza virus, like all viruses, is a hijacker. It quietly slips its way inside cells, steals the machinery inside to make more copies of itself, and then -- having multiplied -- bursts out of the cell to find others to infect.

21 Nov 2014

University of Texas student receives Robert D. Watkins Graduate Research Fellowship

Veronica Garcia, a student at The University of Texas Graduate School of Biomedical Sciences at Houston, has been awarded a Robert D. Watkins Graduate Research Fellowship from the American Society for Microbiology.

21 Nov 2014

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

A recently discovered protein complex known as STING plays a crucial role in detecting the presence of tumor cells and promoting an aggressive anti-tumor response by the body's innate immune system, according to two separate studies published in the Nov. 20 issue of the journal Immunity.

21 Nov 2014

Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

Researchers in Japan have revealed the mechanism that determines the direction of the transportation of eggs in the fallopian tube.

21 Nov 2014

Medical Science News

Study identifies H3.3 protein as key regulator in cellular senescence

Next-generation biomarker detects tumour cells, delivers anti-cancer drugs

Researchers discover why only some patients respond to ipilimumab drug

Research paves way for improving efficacy of ALS treatement

Unique ability helps prolific bacterium to afflict humans, animals and even plants

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

UCLA creates largest-ever protein that self-assembles into molecular 'cage'

Researchers examine genomic landscapes of humans and mice

Exposure to peanut proteins in household dust may trigger peanut allergy

Scientists identify four new genes associated with severe food allergy

TSRI study shows how mutations in Tmie gene can cause deafness from birth

Researchers discover new method to deliver drugs into aggressive tumors

MD Anderson study sheds light on little-known protein complex

MGH investigators develop system to accurately track the process of falling asleep

SRY protein alters specific gender-related tissue in males before birth

Researchers discover a new way to combat influenza virus infection

University of Texas student receives Robert D. Watkins Graduate Research Fellowship

Protein complex plays key role in detecting tumor cells, promotes anti-tumor response

Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

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Why use light scattering to analyze proteins and viral vectors?

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