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Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington's disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University of California San Diego School of Medicine have identified a subunit of a protein that, when expressed, reverse the mutated gene effects responsible for HD.

6 Sep 2016

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

Obesity almost always increases cancer risk and worsens outcomes, but researchers led by scientists at Dana-Farber Cancer Institute report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.

6 Sep 2016

HIF-2 inhibitors could be promising target to combat kidney cancer

A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

6 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

Novel technique offers new insights into growth variation across single cells

A new technique invented at MIT can precisely measure the growth of many individual cells simultaneously.

5 Sep 2016

Scientists discover brain circuit crucial to sleep-wake cycle

Stanford University School of Medicine scientists have identified a brain circuit that's indispensable to the sleep-wake cycle.

5 Sep 2016

New discovery offers way to develop vaccine against highly infectious bacteria

Biochemists at the University of California San Diego have uncovered patterns in the outer protein coat of group A Streptococcus that could finally lead to a vaccine against this highly infectious bacteria--responsible for more than 500,000 deaths a year, including toxic shock syndrome and necrotizing fasciitis or "flesh-eating disease."

5 Sep 2016

Biobank blood storage time may influence test results, study finds

The amount of time a blood sample used for medical research has been stored at a biobank may affect the test results as much as the blood sample provider's age.

5 Sep 2016

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer.

5 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

New article examines why some individuals exhibit stress-resilient characteristics

Adapting to Stress: Understanding the Neurobiology of Resilience, an article recently published in Behavioral Medicine, examines the way our bodies, specifically our brains, become "stress-resilient."

2 Sep 2016

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Osteoporosis particularly affects elderly women: the bone's structure weakens and the risk of suffering fractures rises.

2 Sep 2016

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

Cooperation between Finnish and Chinese research groups has opened up new opportunities for developing treatments targeting aggressive acute lymphoblastic leukaemia (T-ALL).

2 Sep 2016

New discovery could potentially lead to treatments for Crohn's disease

Scientists at the University of British Columbia have made a discovery that could potentially lead to treatments for a debilitating complication of Crohn's disease.

2 Sep 2016

Increased food availability during active season slows cellular aging in animals

Hibernation has long been considered the secret behind the relatively long lifespan of the edible dormouse.

2 Sep 2016

Learning foreign languages can enhance the brain's ability to code information

Scientists from the Higher School of Economics together with colleagues from the University of Helsinki have discovered that learning foreign languages enhances the our brain's elasticity and its ability to code information.

2 Sep 2016

Graphene flakes welded together to form 3-D solids may be suitable for bone implants

Flakes of graphene welded together into solid materials may be suitable for bone implants, according to a study led by Rice University scientists.

2 Sep 2016

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases.

2 Sep 2016

Myeloid-derived suppressor cells may serve as biomarkers for idiopathic pulmonary fibrosis

Researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research, have discovered that the number of myeloid-derived suppressor cells (MDSC) is increased in the blood of patients with idiopathic pulmonary fibrosis (IPF).

2 Sep 2016

Chemists find efficient way to convert organic molecules into new medicines

Opening a broad vista in the search for effective pharmaceuticals, a collaboration of Chinese and U.S. chemists has laid out a highly efficient new method to convert abundant organic molecules into new medicines.

2 Sep 2016

Medical Science News

Experimental co-culture approach facilitates study of cellular events underlying Huntington's disease

Overweight kidney cancer patients live longer than normal-weight counterparts, study shows

HIF-2 inhibitors could be promising target to combat kidney cancer

Researchers describe how genetic mutations cause unnamed neurological disorder

Novel technique offers new insights into growth variation across single cells

Scientists discover brain circuit crucial to sleep-wake cycle

New discovery offers way to develop vaccine against highly infectious bacteria

Biobank blood storage time may influence test results, study finds

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

New article examines why some individuals exhibit stress-resilient characteristics

JMU scientists crystallize new inhibitory antibodies targeting sclerostin

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

New discovery could potentially lead to treatments for Crohn's disease

Increased food availability during active season slows cellular aging in animals

Learning foreign languages can enhance the brain's ability to code information

Graphene flakes welded together to form 3-D solids may be suitable for bone implants

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Myeloid-derived suppressor cells may serve as biomarkers for idiopathic pulmonary fibrosis

Chemists find efficient way to convert organic molecules into new medicines

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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