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NIH-funded investigators develop therapeutic compound effective against malaria

An international team that includes NIH-funded researchers at Stanford University has developed a therapeutic compound that is effective in inhibiting Plasmodium falciparum, one of five species of parasite that infects people with malaria, and the strain which causes the highest number of malaria deaths.

13 Mar 2016

Russian scientists propose new technique to analyze intestinal metagenomes

A group of Russian scientists, among them staff at the Moscow Institute of Physics and Technology, have proposed a new method for the comparison of metagenome-coupled DNA sequences from all of the organisms in a sample of biological material being investigated.

11 Mar 2016

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated -- for the first time -- that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke.

11 Mar 2016

PKM2 enzyme plays major role in early steps of wound healing

An enzyme involved in glucose metabolism in cells plays a major role in the early steps of wound healing, a finding that could lead to new therapeutic approaches for wound care, according to researchers at Georgia State University.

11 Mar 2016

Discovery of new strain of bacteria could aid in developing effective oral probiotic

University of Florida Health researchers have identified a new strain of bacteria in the mouth that may keep bad bacteria in check -- and could lead to a way to prevent cavities using probiotics.The researchers say the findings could lead to the development of a supplement that patients could take orally to prevent cavities

11 Mar 2016

Grid cells involved in broader range of cognitive process than previously thought

Evidence of grid cell activity has been seen in healthy volunteers asked to imagine moving through an environment in new UCL research funded by the Medical Research Council and Wellcome Trust.

11 Mar 2016

New study shows that structural changes within the spine alter vibration response

Magnetic resonance image isn't everything. A new University of Alberta study shows that vibrating the spine may reveal more when it comes to treating back pain. Teaming with the University of South Denmark to study the lumbar spine of twins, Greg Kawchuk and his team demonstrate that structural changes within the spine alter its vibration response significantly.

11 Mar 2016

Enhanced diet helps slow progression of hereditary deafness

An enhanced diet helped reduce hearing loss in mice with the genetic mutation most commonly responsible for childhood deafness, new research suggests.

11 Mar 2016

Conserved gene can act to inhibit lung cancer development, study finds

Scientists believe that "conserved" genes — those found in life forms that range from bacteria to plants, insects and humans — perform vital biological functions across species. And limited research on one of those genes, Nitrilase 1 (Nit1), suggested it acts to inhibit cancer development.

11 Mar 2016

Early life exposure to lead can alter gut microbiota, contribute to increased body weight in adulthood

Exposure to lead during early development can alter the the gut microbiota, increasing the chances for obesity in adulthood, researchers from the University of Michigan School of Public Health have found.

11 Mar 2016

Over- or under-reaction of immune system can be life-threatening

The dilemma of our immune system is comparable to the story of Icarus and Daedalus from Greek mythology. To escape their captivity, Daedalus built wings from feathers and wax for himself and his son. Daedalus warned his son that he must neither fly too high but also not too low, otherwise the sun's heat or the humidity of the sea would destroy his wings and he would crash. After they had successfully escaped, Icarus became boisterous and flew higher and higher until the sun began to melt the wax of his wings and he fell into the sea. Similarly, an over- or under-reaction of our immune system can be life-threatening.

11 Mar 2016

Researchers uncover antitumoral nature of maslinic acid in colon cancer cells

Researchers from the University of Granada, in collaboration with the universities of Barcelona and Jaen, have brought to light the antitumoral nature of maslinic acid (a compound derived from olives) in Caco-2 p53-deficient colon adenocarcinoma cells in the short term.

11 Mar 2016

Scientists map biological networks of genes to gain new insights on disease mechanisms

Innovative software tools allowed the scientists to construct accurate "maps" of gene networks for about 400 different human cell and tissue types, ranging from immune cells to brain tissues, whereas previous studies were limited to just one or few tissues.

11 Mar 2016

People who burn more calories have larger gray matter volume in key brain areas linked to memory, cognition

Whether they jog, swim, garden or dance, physically active older persons have larger gray matter volume in key brain areas responsible for memory and cognition, according to a new study by researchers at the University of Pittsburgh School of Medicine and UCLA.

11 Mar 2016

Breast cancer can be more aggressive in obese people

An international team of researchers, with the participation of the University of Granada, has revealed new data on why breast cancer has a higher incidence and is more aggressive in obese people. The reason is that peritumoral fat (the fat around the tumor) facilitates the expansion and invasion of cancer stem cells (CSCs), which are responsible of the onset and growth of the tumor.

11 Mar 2016

Studies raise hope for new treatments, preventive approaches for schizophrenia

Emerging evidence on the development, "prodromal" characteristics, and long-term course of schizophrenia provide reasons for optimism for developing new treatments and preventive approaches for this devastating disorder, according to the special March/April issue of Harvard Review of Psychiatry.

11 Mar 2016

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Researchers at the University of Southampton are to study why some people are more likely to develop asthma.

11 Mar 2016

Mucus may hold key to better cancer treatment

What do cancer cells and a runny nose have in common? The answer is mucus; and researchers at the Stephenson Cancer Center at the University of Oklahoma have shown it may hold the key to making cancer treatment better.

11 Mar 2016

Scientists sort out mechanism of Alzheimer's disease development

A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King's College London, succeeded in sorting out the mechanism of Alzheimer's disease development and possibly distinguished its key trigger.

11 Mar 2016

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

Medical Science News

NIH-funded investigators develop therapeutic compound effective against malaria

Russian scientists propose new technique to analyze intestinal metagenomes

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

PKM2 enzyme plays major role in early steps of wound healing

Discovery of new strain of bacteria could aid in developing effective oral probiotic

Grid cells involved in broader range of cognitive process than previously thought

New study shows that structural changes within the spine alter vibration response

Enhanced diet helps slow progression of hereditary deafness

Conserved gene can act to inhibit lung cancer development, study finds

Early life exposure to lead can alter gut microbiota, contribute to increased body weight in adulthood

Over- or under-reaction of immune system can be life-threatening

Researchers uncover antitumoral nature of maslinic acid in colon cancer cells

Scientists map biological networks of genes to gain new insights on disease mechanisms

People who burn more calories have larger gray matter volume in key brain areas linked to memory, cognition

Breast cancer can be more aggressive in obese people

Studies raise hope for new treatments, preventive approaches for schizophrenia

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Mucus may hold key to better cancer treatment

Scientists sort out mechanism of Alzheimer's disease development

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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