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Findings could have important implications for personalized treatment of colon cancer

A common observation in oncology is the phenomenon that a patient with a tumor receives a drug and responds very well, but after a few months the cancer comes back and is now resistant to previously administered chemotherapy. What happened? Many mechanisms contribute to explain this effect called "acquired resistance", but today the group Manel Esteller, Director of Epigenetics and Cancer Biology at the Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at the University of Barcelona, describes in the official Journal of the National Cancer Research Center in the United States, The Journal of The National Cancer Institute, the existence of epigenetic differences that explain the lack of response of the tumor recurs.

4 Dec 2013

Research findings pave new ways to treat gastrointestinal disorders

For those living with gastrointestinal disorders, such as ulcers or Crohn's disease, treatment often means quelling uncomfortable symptoms through medications or dietary changes. But what if one day treatment meant doing away with the old gut for a new gut free of inflamed or diseased tissues?

4 Dec 2013

Presence of ERG protein in biopsied prostate tissue increases likelihood of cancer development

Researchers from Weill Cornell Medical College have shown that the presence of a particular protein in biopsied prostate tissue substantially increases the likelihood that cancer will develop in that organ. The discovery will likely help physicians decide how closely to monitor men potentially at risk for the cancer -- among the most confusing and controversial dilemmas in health care.

4 Dec 2013

California scholar receives Wrawemeyer Award for Psychology for proposed somatic marker hypothesis

A California scholar who proposed that emotions play an integral role in human reasoning and decision-making has won the 2014 University of Louisville Grawemeyer Award for Psychology.

4 Dec 2013

A new approach for treating colorectal cancer

Scientists and surgeons at Princess Margaret Cancer Centre have discovered a promising new approach to treating colorectal cancer by disarming the gene that drives self-renewal in stem cells that are the root cause of disease, resistance to treatment and relapse.

4 Dec 2013

CTCs serve as clinical tool to determine patient’s response to chemotherapy

Scientists from Granada have demonstrated, for the first time, that detecting circulating tumour cells (CTCs) in blood and studying the presence of certain genetic markers in them is a technique that allows specialists to predict, with great precision, the response that advanced-cancer patients will have to chemotherapy, as well as the associated secondary effects they may suffer.

4 Dec 2013

Researchers found that blood vessels in face transplant recipients reorganize themselves

For the first time, researchers have found that the blood vessels in face transplant recipients reorganize themselves, leading to an understanding of the biologic changes that happen after full face transplantation.

4 Dec 2013

Blood and tissue sample donations can help advance cancer research

Tucked away in freezers chilled to minus 80 degrees Celsius are blood and tissue samples from Cedars-Sinai patients. The freezers that hold these samples also contain the hopes of investigators determined to uncover new treatments for cancer patients across the globe.

4 Dec 2013

Gladstone scientist devise new molecular sensor that can detect MS at earliest stages

For some, the disease multiple sclerosis attacks its victims slowly and progressively over a period of many years. For others, it strikes without warning in fits and starts. But all patients share one thing in common: the disease had long been present in their nervous systems, hiding under the radar from even the most sophisticated detection methods. But now, scientists at the Gladstone Institutes have devised a new molecular sensor that can detect MS at its earliest stages-even before the onset of physical signs.

3 Dec 2013

Scientists identify enzyme that could lead to better treatment of Alzheimer's disease

St. Jude Children's Research Hospital scientists have identified an enzyme that can halt or possibly even reverse the build-up of toxic protein fragments known as plaques in the brains of mice with Alzheimer's disease. The research appeared in a recent edition of the scientific journal Nature Communications.

3 Dec 2013

Prenatal alcohol exposure impacts brain development and change behavior

Prenatal exposure to alcohol severely disrupts major features of brain development that potentially lead to increased anxiety and poor motor function, conditions typical in humans with Fetal Alcohol Spectrum Disorders, according to neuroscientists at the University of California, Riverside.

3 Dec 2013

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Researchers at MIT and Brigham and Women's Hospital have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells. Using these cells, scientists could develop and test new drugs to treat diseases such as ulcerative colitis.

3 Dec 2013

Axon Sports, GSK Human Performance Lab partner to boost the brains of elite athletes

Axon Sports, a wholly owned subsidiary of Cogstate Limited, has today announced that it has formed a partnership with the GSK Human Performance Lab, a world-class research facility focused on elite human performance.

3 Dec 2013

CUMC researchers make new breakthrough in regenerative medicine

As fast-growing biotech company Rainbow Coral Corp. works to deliver new cutting-edge treatments in the field of regenerative medicine, a major new breakthrough could soon lead to growing new lungs for patients in a laboratory.

3 Dec 2013

EORTC hosts joint session with ESTRO to focus on latest developments in soft tissue sarcoma treatment

The EORTC will host a joint session with ESTRO at ESTRO 33 focusing on current developments in soft tissue sarcoma treatment. It will take place from 14:30- 16:00 on Monday, 07 April 2014 in Vienna, Austria and will be co-chaired by Professors Jean-Yves Blay of the Centre Leon Berard in Lyon, France and past EORTC President and Philippe Maingon of the Centre Georges-Fran-ois-Leclerc in Dijon, France, and Chair of the EORTC Radiation Oncology Group.

3 Dec 2013

New brain connectivity study finds striking differences in the neural wiring of men and women

A new brain connectivity study from Penn Medicine published today in the Proceedings of National Academy of Sciences found striking differences in the neural wiring of men and women that's lending credence to some commonly-held beliefs about their behavior.

3 Dec 2013

Medical Science News

Findings could have important implications for personalized treatment of colon cancer

Research findings pave new ways to treat gastrointestinal disorders

Presence of ERG protein in biopsied prostate tissue increases likelihood of cancer development

California scholar receives Wrawemeyer Award for Psychology for proposed somatic marker hypothesis

A new approach for treating colorectal cancer

CTCs serve as clinical tool to determine patient’s response to chemotherapy

Researchers found that blood vessels in face transplant recipients reorganize themselves

Blood and tissue sample donations can help advance cancer research

Gladstone scientist devise new molecular sensor that can detect MS at earliest stages

Scientists identify enzyme that could lead to better treatment of Alzheimer's disease

Prenatal alcohol exposure impacts brain development and change behavior

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Axon Sports, GSK Human Performance Lab partner to boost the brains of elite athletes

CUMC researchers make new breakthrough in regenerative medicine

EORTC hosts joint session with ESTRO to focus on latest developments in soft tissue sarcoma treatment

New brain connectivity study finds striking differences in the neural wiring of men and women

Conjuring up visual image in mind has corresponding effect on size of pupils

Toshiba's new ultrasound technology depicts blood flow with more detail and accuracy

3T MRI scanner allows Polish scientists to perform structural and functional imaging of human brain

Microneedle technique may provide a painless way to deliver drugs, vaccines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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