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Compound responsible for chilis' heat may help kill prostate cancer cells

Capsaicin, the compound responsible for chilis' heat, is used in creams sold to relieve pain, and recent research shows that in high doses, it kills prostate cancer cells. Now researchers are finding clues that help explain how the substance works. Their conclusions suggest that one day it could come in a new, therapeutic form.

10 Sep 2015

CRISPR tool streamlines gene editing

Within the past few years, a new technology has made altering genes in plants and animals much easier than before. The tool, called CRISPR/Cas9 or just CRISPR, has spurred a flurry of research that could one day lead to hardier crops and livestock, as well as innovative biomedicines. But along with potential benefits, it raises red flags, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society.

10 Sep 2015

Liver failure patients may benefit from CSF-1 treatment that aids the immune system to combat infections

Patients with liver failure could benefit from a treatment that helps the immune system to combat infections linked to the condition, research suggests.

10 Sep 2015

Worldwide Protein Data Bank symposium focuses on multi-scale structural biology

The symposium titled with "Integrative Structural Biology with Hybrid Methods" is held focusing on the multi-scale structural biology, which aims to analyze structures of protein molecules and their assemblies, cellular machines, organelle, and even living cells and organisms by the hybrid methods, integrating many different technologies, such as chemical cross-links, MS spectrometry, FRET, Super-resolution microscopy, X-ray diffraction, NMR, and Computer modeling, in addition to Cryo-electron microscopy that has been attracting much attention these days.

10 Sep 2015

Nerve damage caused by leprosy linked to changes in the brain of patients

Brain plasticity is the ability of the brain to change both anatomically and functionally in response to changes in the body or in the environment.

10 Sep 2015

Simple stem cell production method shows promise in mice for treating IPF

In a small pilot study, researchers from North Carolina State University have demonstrated a rapid, simple way to generate large numbers of lung stem cells for use in disease treatment. This method of harvesting and growing a patient's own lung stem cells shows promise in mice for treating idiopathic pulmonary fibrosis (IPF), and could one day provide human IPF sufferers with an effective, less invasive method of treatment for their disease.

10 Sep 2015

Riddell, TGen start third year of study to advance concussion treatment with ASU's football program

Riddell, the leader in football helmet technology and innovation, and the Translational Genomics Research Institute, a leader in cutting-edge genomic research, today announced they have begun the third year of a study to advance concussion detection and treatment with the Pac-12's Arizona State University and its Sun Devil football program.

10 Sep 2015

Research opens up potential new pathways to vaccine development against HA-MRSA

New research led by NYU Langone Medical Center has uncovered why a particular strain of Staphylococcus aureus -- known as HA-MRSA -- becomes more deadly than other variations. These new findings open up possible new pathways to vaccine development against this bacterium, which the Centers for Disease Control and Preventions says accounts for over 10,000 deaths annually, mostly among hospital patients.

10 Sep 2015

UMD awarded $1.8 million NIH grant to expand functionality of genomic data analysis tools

A University of Maryland genomics expert has been awarded a $1.8 million grant from the National Institutes of Health to expand the functionality of open source data visualization software that can help identify genomic markers for cancer and other diseases.

9 Sep 2015

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

Alzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death among the elderly and the leading cause of dementia. Predictions are that the number of AD cases will quadruple by 2050.

9 Sep 2015

New $2.8 million NIH grant to help researchers find better treatments for hemorrhagic strokes

Developing better treatments and an improved understanding of the biology behind brain injury from hemorrhagic strokes is the main goal of a three-year $2.8 million grant to the Translational Genomics Research Institute, Phoenix Children's Hospital, and Barrow Neurological Institute.

9 Sep 2015

Nearly 50% of testicular cancer risk passed down genetically, new study reports

Almost half of the risk of developing testicular cancer comes from the DNA passed down from our parents, a new study reports.

9 Sep 2015

UI scientists discover protein that causes muscle weakness and loss during aging

As we grow older, we lose strength and muscle mass. However, the cause of age-related muscle weakness and atrophy has remained a mystery.

9 Sep 2015

Research provides new approach for studying neural circuits that control behavior

Researchers at the University of Massachusetts Medical School are the first to show that it's possible to reverse the behavior of an animal by flipping a switch in neuronal communication.

9 Sep 2015

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

Clostridium difficile is a common cause of infection and diarrhea in hospitalized patients, but a new study by UC Davis pathologists suggests that many patients are mistakenly diagnosed and do not need antibiotic treatment. As a result, patients are likely being over-diagnosed and over-treated, adding to concerns about antibiotic resistance, damage to the "good" bacteria that live in people's intestines, and increased health-care costs.

9 Sep 2015

Dietary uptake of microRNAs certainly insufficient to affect physiological functions, reveal ETH biologists

The scientific world was astonished when, in 2011, Chinese researchers claimed to have found evidence suggesting that minute fragments of plant genetic material - so-called microRNA molecules - of rice ingested from food could play a role in regulating physiological processes in the human body. If this is indeed true, it might even be possible to deliberately modify human physiological functions via this route, for instance by incorporating microRNAs into novel functional foods.

9 Sep 2015

New study reveals conflicting role of two subtypes of pancreatic cancer stroma

Dense surrounding tissue can block drugs from reaching pancreatic cancer tumors, but it can also help prevent the cancer from spreading. Now a new study by UNC Lineberger Comprehensive Cancer Center researchers and collaborators helps explain the conflicting role of the surrounding tissue known as stroma. In the study, the researchers revealed that based on molecular characteristics, there are two subtypes of pancreatic cancer stroma.

9 Sep 2015

New molecule shows efficacy in inhibiting inflammation, preventing premature delivery in murine models

Premature births are intimately linked with inflammation of the uterine tissue, a biological response which induces contractions and preterm labor. In their search for a mean to prevent this phenomenon and complications related to deliveries occurring before 37 weeks of gestation, researchers at CHU Sainte-Justine and University of Montreal discovered an agent that shows efficacy in inhibiting inflammation and preventing or delaying uterine contractions and premature delivery in murine models - without adversely affecting the fetus or the mother.

9 Sep 2015

Scientists identify new drug target to treat heart arrhythmias

Scientists at The Ohio State University Davis Heart and Lung Research Institute have identified a new target they hope will help make the next drug discovery for patients suffering from heart arrhythmias happen sooner.

9 Sep 2015

Researchers use stem cell-derived 'mini-brains' to identify drug candidate for rare neurological disorder

Using "mini-brains" built with induced pluripotent stem cells derived from patients with a rare, but devastating, neurological disorder, researchers at University of California, San Diego School of Medicine say they have identified a drug candidate that appears to "rescue" dysfunctional cells by suppressing a critical genetic alteration.

9 Sep 2015

Medical Science News

Compound responsible for chilis' heat may help kill prostate cancer cells

CRISPR tool streamlines gene editing

Liver failure patients may benefit from CSF-1 treatment that aids the immune system to combat infections

Worldwide Protein Data Bank symposium focuses on multi-scale structural biology

Nerve damage caused by leprosy linked to changes in the brain of patients

Simple stem cell production method shows promise in mice for treating IPF

Riddell, TGen start third year of study to advance concussion treatment with ASU's football program

Research opens up potential new pathways to vaccine development against HA-MRSA

UMD awarded $1.8 million NIH grant to expand functionality of genomic data analysis tools

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

New $2.8 million NIH grant to help researchers find better treatments for hemorrhagic strokes

Nearly 50% of testicular cancer risk passed down genetically, new study reports

UI scientists discover protein that causes muscle weakness and loss during aging

Research provides new approach for studying neural circuits that control behavior

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

Dietary uptake of microRNAs certainly insufficient to affect physiological functions, reveal ETH biologists

New study reveals conflicting role of two subtypes of pancreatic cancer stroma

New molecule shows efficacy in inhibiting inflammation, preventing premature delivery in murine models

Scientists identify new drug target to treat heart arrhythmias

Researchers use stem cell-derived 'mini-brains' to identify drug candidate for rare neurological disorder

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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