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Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

The development of a probe to measure the body's immune function could lead to more accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs, according to research conducted at the University of North Carolina.

21 Nov 2013

Brown University biologists find way to measure effects of aging

Biologists at Brown University have found a way to measure the effects of aging by watching the ebb and flow of chromatin, a structure along strands of DNA that either silences or permits gene expression. In several newly published experiments they show that gene silencing via chromatin in fruit flies declines with age.

21 Nov 2013

Researchers engineering first-ever living, three-dimensional human arrhythmic tissue

A foundational study published in top biomedical journal PNAS (Proceedings of the National Academy of Sciences) this week by researchers at the University of Toronto's Institute of Biomaterials & Biomedical Engineering and the McEwen Centre for Regenerative Medicine have identified the optimal structure and cell ratio associated with heart function - and the discovery has already led the team to another research first: the engineering of the first-ever living, three-dimensional human arrhythmic tissue.

21 Nov 2013

New method uses lab-on-a-chip device and cell phone to determine concentration of molecules

In developing nations, rural areas, and even one's own home, limited access to expensive equipment and trained medical professionals can impede the diagnosis and treatment of disease.

21 Nov 2013

Buck Institute research provides method to study sarcopenia

Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches help alter the way our cells act and are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle. The study, appearing on line in Aging Cell, provides a method to study sarcopenia, the degenerative loss of muscle mass that begins in middle age.

21 Nov 2013

Covagen, TRL expand research collaboration to generate bispecific FynomAb

Covagen and Tanabe Research Laboratories U.S.A, Inc., a fully owned subsidiary of Mitsubishi Tanabe Pharma Corporation, today announced that they expanded their strategic research collaboration. MTPC and TRL have nominated a first bispecific FynomAb for formal preclinical development which triggered an undisclosed milestone payment. MTPC and TRL also exercised an option for a second bispecific FynomAb program based on the parties' research and licensing agreement signed in October 2012.

21 Nov 2013

Cedars-Sinai study presents new insights into mechanisms underlying the symptoms of autism

In what are believed to be the first studies of their kind, Cedars-Sinai researchers recording the real-time firing of individual nerve cells in the brain found that a specific type of neuron in a structure called the amygdala performed differently in people who suffer from autism spectrum disorder than in those who do not.

21 Nov 2013

Study: Connections in the brain become stronger during sleep as children age

While young children sleep, connections between the left and the right hemispheres of their brain strengthen, which may help brain functions mature, according to a new study by the University of Colorado Boulder.

21 Nov 2013

Long-term cocaine abuse may be linked with deficits in parts of brain overseeing own behavior

New research from the Icahn School of Medicine at Mount Sinai reveals long-term cocaine abuse may be associated with deficits in parts of the brain involved in monitoring and overseeing one's own behavior.

21 Nov 2013

Changing texture can make bread taste salty even if salt content is reduced, say scientists

Want to make bread taste pleasantly salty without adding more salt? Change the bread's texture so it is less dense, say scientists. They report in ACS' Journal of Agricultural and Food Chemistry that simply making the pores, or holes, larger can make people perceive bread as having saltier taste.

21 Nov 2013

Predicting a person's tall stature from DNA is feasible, shows new study

Predicting adult body height from genetic data is helpful in several areas such as pediatric endocrinology and forensic investigations. However, despite large international efforts to catalogue the genes that influence the stature of humans, knowledge on genetic determinants of adult body height is still incomplete. Now DNA-based prediction of taller-than-average body height is feasible, as reported by researchers from the Netherlands and Sweden in an article published in Springer's journal Human Genetics

21 Nov 2013

Findings show how cancer and aging are tightly interconnected

Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe heritable alterations caused by mechanisms other than by changes in DNA sequence. The discovery, published in the February 2014 issue of Epigenetics, illustrates how cancer and aging are tightly interconnected processes by identifying epigenetic alterations present in the normal aging breast that may increase disease risk in cancer-free individuals.

21 Nov 2013

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

Every day, the human body produces new cells to regenerate tissues and repair those that have suffered injury. Each time this happens, the cells make copies of their DNA that they will pass on to the resulting daughter cells. This process of copying the DNA, also called replication, is very delicate, given that it can generate severe alterations in the DNA that are associated with malignant transformation or ageing.

21 Nov 2013

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

The UK’s first gene therapy trial for advanced heart failure, CUPID 2, has officially begun at the Golden Jubilee National Hospital; with the first candidate recently being administered with a dose of the MYDICAR treatment.

21 Nov 2013

Ability to learn foreign speech reveals in brain activity

A new study by University of Houston (UH) researchers may lead to dramatic changes in the way language is taught and learned - especially a second language.

21 Nov 2013

Caffeine in coffee may help small blood vessels work better

The caffeine in a cup of coffee might help your small blood vessels work better, according to research presented at the American Heart Association's Scientific Sessions 2013.

20 Nov 2013

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Inovio Pharmaceuticals, Inc. announced today that preclinical testing of a DNA synthetic vaccine for the virulent Middle East Respiratory Syndrome coronavirus (MERS) induced robust and durable immune responses, demonstrating the potential for a SynCon DNA vaccine to prevent and treat this deadly virus.

20 Nov 2013

Medical Science News

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

Brown University biologists find way to measure effects of aging

Researchers engineering first-ever living, three-dimensional human arrhythmic tissue

New method uses lab-on-a-chip device and cell phone to determine concentration of molecules

Buck Institute research provides method to study sarcopenia

Covagen, TRL expand research collaboration to generate bispecific FynomAb

Cedars-Sinai study presents new insights into mechanisms underlying the symptoms of autism

Study: Connections in the brain become stronger during sleep as children age

Long-term cocaine abuse may be linked with deficits in parts of brain overseeing own behavior

Changing texture can make bread taste salty even if salt content is reduced, say scientists

Predicting a person's tall stature from DNA is feasible, shows new study

Findings show how cancer and aging are tightly interconnected

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

Ability to learn foreign speech reveals in brain activity

Caffeine in coffee may help small blood vessels work better

DNA vaccine demonstrates potential to prevent and treat deadly MERS coronavirus

Parkinson's Institute, Population Diagnostics discover new genes relevant to Parkinson's disease

DNA-damaging drug and MK2 inhibitor combination could be effective against cancer

Staphylococcus Aureus Bacteria anticipates and turns immune defenses against the host

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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