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Natural extract from India's neem tree shows promise against pancreatic cancer

A natural extract derived from India's neem tree could potentially be used to treat pancreatic cancer, according to a new study in the journal Scientific Reports.

12 Feb 2016

Discovery throws light on how human diseases work

Researchers from the University of Warwick have discovered how cells in the human body build their own 'railway networks', throwing light on how diseases such as bowel cancer work.

12 Feb 2016

Exercise-associated bone loading during adolescence, young adulthood benefits bone density in adulthood

Men have many reasons to add high-impact and resistance training to their exercise regimens; these reasons include building muscle and shedding fat. Now a University of Missouri researcher has determined another significant benefit to these activities: building bone mass.

12 Feb 2016

Transition to family foods drives development of infant gut microbiota

After the age of nine months, the development of the infant gut microbiota is driven by the transition to family foods, not maternal obesity, according to results from a new study. The study was published online this week in mSphere, an open-access journal of the American Society for Microbiology.

11 Feb 2016

TAU research highlights neuroprotective potential of protein-protectant drug candidate SKIP

Activity-dependent neuroprotective protein (ADNP), essential for brain formation, is frequently mutated in children on the autism spectrum. In older men and women, ADNP expression in the blood is correlated with cognition and further altered in Alzheimer's disease.

11 Feb 2016

Novel test could help get best treatment for advanced bowel cancer patients

A NEW test could help patients with advanced bowel cancer get the best treatment for their disease, according to a Cancer Research UK clinical trial published today (Thursday) in JAMA Oncology.

11 Feb 2016

Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes

New research on the blood lipid-lowering protein FGF21 shows how it redistributes fatty acids by two distinct mechanisms. The discovery could lead to improved pharmaceutical treatment for type 2 diabetes and other obesity-related diseases.

11 Feb 2016

GEMS project to explore events leading to MS in at-risk individuals

A team of investigators at Brigham and Women's Hospital and the National Institute of Neurological Disorders and Stroke has launched a study of individuals at risk for multiple sclerosis (MS). By focusing on first-degree family members of MS patients, the research team seeks to better understand the sequence of events that leads some people to develop the disease.

11 Feb 2016

UW-Madison research team starts work on Zika virus infection

In October, when David O'Connor last visited Brazil as part of a decade-long research program studying drug-resistant strains of HIV, one of his Brazilian collaborators had a request.

11 Feb 2016

CMU researchers create robotically-driven experimentation system to reduce drug discovery cost

Researchers from Carnegie Mellon University have created the first robotically driven experimentation system to determine the effects of a large number of drugs on many proteins, reducing the number of necessary experiments by 70 percent.

11 Feb 2016

Yale Cancer Center researchers identify cause of myeloma

Yale Cancer Center researchers have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published in the Feb. 11 issue of the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated.

11 Feb 2016

Simple physics may play key role in helping the body to fight infection

Simple physics may play a larger role than previously thought in helping control key bodily processes - such as how the body fights infection.

11 Feb 2016

CHLA researchers develop novel model for studying neonatal lung disorder

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies. Their study, published in PLOS ONE on February 10, describes the first model that allows investigators to consider the chronic effects of developmental lung disease.

11 Feb 2016

Alcohol appears to impair the body's ability to keep gut bacteria in check

Alcohol itself can directly damage liver cells. Now researchers at University of California, San Diego School of Medicine report evidence that alcohol is also harmful to the liver for a second reason — it allows gut bacteria to migrate to the liver, promoting alcohol-induced liver disease.

11 Feb 2016

Penn investigators explore new treatment option for cocaine dependence

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence.

11 Feb 2016

Cardiac MRI imaging assesses myocardial damage

In a world-first, researchers from Charité-Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine (MDC) have performed cardiac MRI imaging using a 7T MRI scanner in a patient-based study.

11 Feb 2016

Study provides new insight into how drug addicts' brains wired differently

A study out today provides new insight into how the brains of drug addicts may be wired differently. The findings, which appear in the journal Psychopharmacology, show that while drug users have very strong motivation to seek out "rewards," they exhibit an impaired ability to adjust their behavior and are less fulfilled once they have achieved what they desire.

11 Feb 2016

Starting marijuana at younger age may hinder brain development

The age at which an adolescent begins using marijuana may affect typical brain development, according to researchers at the Center for BrainHealth at The University of Texas at Dallas. In a paper recently published in Developmental Cognitive Neuroscience, scientists describe how marijuana use, and the age at which use is initiated, may adversely alter brain structures that underlie higher order thinking.

11 Feb 2016

Researchers devise lipid-based diets to relieve symptoms of Alzheimer's disease

Alzheimer´s disease (AD) is the most common disease underlying memory problems and dementia in the elderly. One of the invariable pathologies in AD is degeneration of cholinergic synapses in brain cortex and hippocampus.

11 Feb 2016

Study holds promise for new alternatives to treat leukemia

Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous.

11 Feb 2016