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Research reveals that deletion of Epac1 gene protects from fatal rickettsiosis

Researchers at the University of Texas Medical Branch at Galveston have discovered a way to block a disease pathway that could be a breakthrough in defeating some of the world's most devastating human infections.

14 Dec 2013

Neuroscientists use new technique to enhance a form of self-control through brain stimulation

If you have ever said or done the wrong thing at the wrong time, you should read this. Neuroscientists at The University of Texas Health Science Center at Houston and the University of California, San Diego, have successfully demonstrated a technique to enhance a form of self-control through a novel form of brain stimulation.

14 Dec 2013

Scientists reveal how two genes interact to kill broad range of cancer cells

Scientists from Virginia Commonwealth University Massey Cancer Center have revealed how two genes interact to kill a wide range of cancer cells. Originally discovered by the study's lead investigator Paul B. Fisher, M.Ph., Ph.D., the genes known as mda-7/IL-24 and SARI could potentially be harnessed to treat both primary and metastatic forms of brain, breast, colon, lung, ovary, prostate, skin and other cancers.

14 Dec 2013

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses.

14 Dec 2013

Researchers study zebrafish embryo skin to find link between low calcium and colon cancer

A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.

14 Dec 2013

MD Anderson researcher earns Breakthrough Prize in Life Sciences

Basic science research that exposed vital details of cancer's defense against the immune system, revealing an entirely new way to combat these diseases, has earned Jim Allison, Ph.D., a Breakthrough Prize in Life Sciences.

14 Dec 2013

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.

13 Dec 2013

Skin cells can migrate over regions devoid of support from extracellular matrix

A team of researchers from the National University of Singapore have discovered that outer skin cells are able to unite to form suspended "bridges" during wound healing. The new findings will pave the way for tissue engineering, such as the design of artificial skin, and better wound treatment.

13 Dec 2013

Spaceflights cause cellular-level damage and may lead to long-term vision problems

Those who travel to space are rewarded with a beautiful sight - planet Earth. But the effects of space travel on the human sense of sight aren't so beautiful. More than 30 percent of astronauts who returned from two-week space shuttle missions and 60 percent who spent six months aboard the International Space Station were diagnosed with eye problems. Two recent investigations examined mechanisms that may explain eye changes in spaceflight, help find ways to minimize this health risk to astronauts and eventually prevent and treat eye diseases on Earth.

13 Dec 2013

Nature Medicine selects CNIO study as most important discovery in regenerative medicine

The prestigious journal Nature Medicine has taken a look at the year and chosen one of the Spanish National Cancer Research Centre's (CNIO) studies as the most important in the stem cell category for its special December edition.

13 Dec 2013

Polyunsaturated fatty acids play key role in embryonic development

One classical question in developmental biology is how different tissue types arise in the correct position of the developing embryo. While one signaling pathway that controls this process has been well described, unexpected findings from a team led by Carnegie's Steven Farber reveal the importance of polyunsaturated fatty acid metabolism in this process. It is published online December 12 in Developmental Cell.

13 Dec 2013

Psychology researchers and practitioners still hold different beliefs about repressed memories

Skepticism about repressed traumatic memories has increased over time, but new research shows that psychology researchers and practitioners still tend to hold different beliefs about whether such memories occur and whether they can be accurately retrieved.

13 Dec 2013

New mutations in the estrogen receptor drive strong drug resistance exhibited by human breast tumors

Human breast tumors transplanted into mice are excellent models of metastatic cancer and are providing insights into how to attack breast cancers that no longer respond to the drugs used to treat them, according to research from Washington University School of Medicine in St. Louis.

13 Dec 2013

Georgia State University creates new research center to advance nanotechnology and biomedicine

The Center for Nano-Optics, a research center whose focus on the science of developing tools and instruments as small as 1,000 times thinner than a human hair could lead to major breakthroughs in technology and biomedicine, has been created at Georgia State University.

13 Dec 2013

New test may help decrease risk of suicidality in patients treated with antidepressants

The new test, based on research carried out at the Max Planck Institute of Psychiatry, should help doctors to decrease the risk of suicidality in patients treated with antidepressants who show certain gene markers. Sundance is completing a new round of funding to extend the initial validation results reported by the Institute. The company plans to launch the test immediately as a laboratory developed test. In addition, clinical studies in support of a U.S. Food and Drug Administration submission for market clearance, CE marking and reimbursement will be initiated. Sundance expects to submit its application to the agencies within 18 months.

13 Dec 2013

Genomic tests help in selecting the most effective therapy for breast cancer

Genomic tests that determine the molecular subtype of a woman's breast cancer provide a more precise prognosis and valuable guidance about the best treatment, according to new research led by Massimo Cristofanilli, M.D, Director of the Jefferson Breast Care Center at the Kimmel Cancer Center (KCC) and Thomas Jefferson University and Hospitals.

13 Dec 2013

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Researchers conduct a memory study, scan a participant's brain, and find more than they bargain for: a tumor. What do the researchers owe the participant? What does the participant want to know?

13 Dec 2013

Transport of bacterial substrates through injectisome observed almost in real time

When attacking body cells, bacteria, such as salmonellae or Yersinia (plague pathogens), inject specific bacterial proteins through hollow, syringe-like structures - called injectisomes - into the host cells. These substances reprogram the cells and can thus overcome their defense. From then on, they can infiltrate the cells unhindered in large numbers, and trigger diseases such as typhus, plague, or cholera.

13 Dec 2013

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

A research team from The University of Nottingham has helped uncover a second rare genetic mutation which strongly increases the risk of Alzheimer's disease in later life.

13 Dec 2013

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

A new individualized systems medicine strategy, developed at the Institute for Molecular Medicine Finland FIMM and the Helsinki University Central Hospital, enables a selection of potentially effective cancer therapies for individual patients. The promising results achieved by applying this strategy to chemoresistant adult acute myeloid leukemia patients have been recently published in the Cancer Discovery journal.

13 Dec 2013

Medical Science News

Research reveals that deletion of Epac1 gene protects from fatal rickettsiosis

Neuroscientists use new technique to enhance a form of self-control through brain stimulation

Scientists reveal how two genes interact to kill broad range of cancer cells

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

Researchers study zebrafish embryo skin to find link between low calcium and colon cancer

MD Anderson researcher earns Breakthrough Prize in Life Sciences

Deep genome sequencing used to predict clinical outcomes in patients with breast cancer tumors

Skin cells can migrate over regions devoid of support from extracellular matrix

Spaceflights cause cellular-level damage and may lead to long-term vision problems

Nature Medicine selects CNIO study as most important discovery in regenerative medicine

Polyunsaturated fatty acids play key role in embryonic development

Psychology researchers and practitioners still hold different beliefs about repressed memories

New mutations in the estrogen receptor drive strong drug resistance exhibited by human breast tumors

Georgia State University creates new research center to advance nanotechnology and biomedicine

New test may help decrease risk of suicidality in patients treated with antidepressants

Genomic tests help in selecting the most effective therapy for breast cancer

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Transport of bacterial substrates through injectisome observed almost in real time

Researchers uncover second rare genetic mutation linked to higher risk of Alzheimer's disease

Novel ISM strategy enables selection of potentially effective cancer therapies for patients

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Why use light scattering to analyze proteins and viral vectors?

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