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High concentrations of serum omega-3 fatty acids may help reduce risk of type 2 diabetes

High concentrations of serum long-chain omega-3 fatty acids may help reduce the risk of type 2 diabetes, according to a University of Eastern Finland study published recently in Diabetes Care. The sources of these fatty acids are fish and fish oils.

14 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Researchers at the University of Massachusetts Medical School (UMMS) have been commissioned by the Alpha-1 Project (TAP) to develop a PiZ antibody. The antibody will be used to track the presence of mutant alpha-1 PiZ protein in human blood serum, an essential tool in testing potential therapies for Alpha-1 Antitrypsin Deficiency (Alpha-1).

13 Jan 2014

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Scientists have made an important advance in understanding how a subset of bacterial cells escape being killed by many antibiotics.

10 Jan 2014

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Findings of a preliminary study published in The Lancet Respiratory Medicine suggest that a patient’s own bone-marrow stromal (stem) cells could be used to treat multidrug-resistant (MDR) and extensively-drug (XDR) tuberculosis.

10 Jan 2014

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

Producing brightly speckled red and green snapshots of many different tissues, Johns Hopkins researchers have color-coded cells in female mice to display which of their two X chromosomes has been made inactive, or “silenced.”

10 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Foundation Medicine announces discovery of high incidence of ERBB2 alterations in MPUC patients

Foundation Medicine, Inc. today announced the discovery of a high incidence of ERBB2 (HER2) extracellular domain alterations in patients with micropapillary urothelial carcinoma, a particularly aggressive form of urinary bladder cancer, using FoundationOne. The research was published in the current edition of Clinical Cancer Research.

10 Jan 2014

Life Technologies, Quest Diagnostics sign multi-year license and supply agreement

Life Technologies has completed a multi-year license and supply agreement with Quest Diagnostics, the world's leading provider of diagnostic information services, that gives Quest rights to develop molecular tests on the Ion Torrent next-generation sequencing platform. Under the agreement, Quest may use the platform and related consumables to independently develop new tests for numerous areas of their business.

From Quest Diagnostics 10 Jan 2014

SHY hypothesis challenges theory that sleep strengthens brain connections

Why do animals ranging from fruit flies to humans all need to sleep? After all, sleep disconnects them from their environment, puts them at risk and keeps them from seeking food or mates for large parts of the day.

10 Jan 2014

Researchers examine genetic variants associated with increased risk of type 2 diabetes

Contrary to a common belief, researchers have shown that genetic regions associated with increased risk of type 2 diabetes were unlikely to have been beneficial to people at stages through human evolution.

10 Jan 2014

Researchers deploy potential new weapon against HIV

Researchers at the UNC School of Medicine have deployed a potential new weapon against HIV - a combination therapy that targets HIV-infected cells that standard therapies cannot kill.

10 Jan 2014

Researchers reveal newest weapon to visualize shape and motion of RNA

Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.

10 Jan 2014

Biologists discover new pathway for repairing nerve cells

Penn State University molecular biologists have discovered a brand-new pathway for repairing nerve cells that could have implications for faster and improved healing. The researchers describe their findings in a paper titled "Dendrite injury triggers DLK-independent regeneration," which will be published in the 30 January 2014 issue of the journal Cell Reports.

10 Jan 2014

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types, transforming - among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself.

10 Jan 2014

New study gives hope for novel glioblastoma multiforme treatment

A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.

9 Jan 2014

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Very low doses of a drug used to treat certain types of cancer protect the insulin-producing cells in the pancreas and prevent the development of diabetes mellitus type 1 in mice. The medicine works by lowering the level of so-called sterile inflammation. The findings have been made by researchers from the University of Copenhagen, the Technical University of Denmark and the University of Southern Denmark working with researchers in Belgium, Italy, Canada, Netherlands and the USA.

9 Jan 2014

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.

9 Jan 2014

Study provides details to help scientists design better vaccines for Plasmodium vivax

A form of malaria common in India, Southeast Asia and South America attacks human red blood cells by clamping down on the cells with a pair of proteins, new research at Washington University School of Medicine in St. Louis has revealed.

9 Jan 2014

Medical Science News

High concentrations of serum omega-3 fatty acids may help reduce risk of type 2 diabetes

At-home paper test can help spot early symptoms of cognitive issues

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Scientists progress towards understanding how some bacterial cells escape being killed by antibiotics

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Foundation Medicine announces discovery of high incidence of ERBB2 alterations in MPUC patients

Life Technologies, Quest Diagnostics sign multi-year license and supply agreement

SHY hypothesis challenges theory that sleep strengthens brain connections

Researchers examine genetic variants associated with increased risk of type 2 diabetes

Researchers deploy potential new weapon against HIV

Researchers reveal newest weapon to visualize shape and motion of RNA

Biologists discover new pathway for repairing nerve cells

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

New study gives hope for novel glioblastoma multiforme treatment

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

Study provides details to help scientists design better vaccines for Plasmodium vivax

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From Discovery Biology to ELRIG Chair

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