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Researchers reveal 3-D structure of biologically active DNA

Using a multidisciplinary approach, researchers, led by those at Baylor College of Medicine, revealed in unprecedented detail the three-dimensional structure of biologically active DNA. A report on their work appears online in the journal Nature Communications.

12 Oct 2015

Exposure to acrylamide through STP use much smaller than exposure from diet or cigarette smoking

The first comprehensive assessment of the acrylamide content of smokeless tobacco products (STPs) has shown that exposure to acrylamide through STP use is much smaller than --approximately 1% of -- exposure from the diet or from cigarette smoking.

12 Oct 2015

York scientists target specific sodium channel to prevent breast cancer

Scientists at the University of York, using clinical specimens from charity Breast Cancer Now's Tissue Bank, have conducted new research into a specific sodium channel that indicates the presence of cancer cells and affects tumour growth rates.

12 Oct 2015

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Rhesus monkeys were completely protected from the deadly Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, according to research findings to be presented tomorrow at the IDWeek conference.

12 Oct 2015

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Chronic pain results from disease or trauma to the nervous system. Damaged nerve fibres with heightened responses to normal stimuli send incorrect messages to pain centres in the brain. This phenomenon, called "peripheral and central sensitization" is one of the key mechanisms involved in the condition which touches people with diabetes, cancer, and those suffering from multiple sclerosis, among others.

12 Oct 2015

Glycan binding proteins modify parasite infection in cells of the heart muscle

Chagas disease is the main cause of infectious heart disease in Latin America. Researchers from the INGEBI and IBYME Institutes in Argentina explored the effect of glycan binding protein interactions between the human host and Typanosoma cruzi parasite. They found that a glycan binding protein expressed in humans modified the infection in cells of the heart muscle, showing the importance of galectins in the response to parasite infection.

12 Oct 2015

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.

12 Oct 2015

UConn researchers sequence RNA of most complicated gene

UConn researchers have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone.

From Oxford Nanopore Technologies 12 Oct 2015

YK-4-279 compound works against some forms of leukemia: Study

A compound discovered and developed by a team of Georgetown Lombardi Comprehensive Cancer Center researchers that halts cancer in animals with Ewing sarcoma and prostate cancer appears to work against some forms of leukemia, too.

12 Oct 2015

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Scientists are now better able to predict how quickly the HIV virus will return after individuals stop treatment following a discovery by researchers at UNSW Australia and the University of Oxford.

12 Oct 2015

Physicists use diamonds to detect early-stage cancerous tumours

Physicists from the University of Sydney have devised a way to use diamonds to identify cancerous tumours before they become life threatening.

12 Oct 2015

Scientists can now use skin samples from older patients to grow brain cells

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people's brains, will be a boon to scientists studying age-related diseases like Alzheimer's and Parkinson's.

9 Oct 2015

Scientists engineer stem cells to better understand mechanisms behind leukemia

Scientists engineered stem cells to better understand the mechanisms behind a form of leukemia caused by changes in a key gene, according to a study led by Mount Sinai researchers and published online today in the journal Cell Reports.

9 Oct 2015

Artificial lung model could provide better understanding of health risks associated with airborne pollution

A life-sized artificial human lung created at the Technion-Israel Institute of Technology is the first diagnostic tool for understanding in real time how tiny particles move and behave in the deepest part of the human lungs (alveolar tissue).

9 Oct 2015

Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

During cell division, each metaphase chromosome contains a single enormously long DNA molecule that is associated with histone proteins and forms a long chromatin filament with many nucleosomes.

9 Oct 2015

HDL not so good in protecting women against atherosclerosis, study shows

What has previously been known as good cholesterol--high density lipoprotein (HDL)--has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause. That's according to a new study from the University of Pittsburgh Graduate School of Public Health that was presented last week at the annual meeting of The North American Menopause Society in Las Vegas.

9 Oct 2015

Scientists map EGFRvIII mutant that causes brain cancer

A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the reading of the genome to fuel the growth of the brain cancer glioblastoma multiforme (GBM) and--most important--how each process is linked to the other.

9 Oct 2015

Gene therapy prevents neuronal death, disease effects in experimental model of PD

An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of PD patients develop progressive disease showing signs of dementia similar to Alzheimer's disease.

9 Oct 2015

Leading experts to discuss role of laboratory medicine in personalized medicine

Join the American Association for Clinical Chemistry (AACC) and leading experts in laboratory medicine and diagnostic testing for a discussion of how laboratory medicine is driving the future of personalized medicine and the policies to support these new technologies.

9 Oct 2015

Father’s life experiences can affect health, development of both children and grandchildren

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad's behaviour or environment. Or even your grandfather's.

9 Oct 2015

Medical Science News

Researchers reveal 3-D structure of biologically active DNA

Exposure to acrylamide through STP use much smaller than exposure from diet or cigarette smoking

York scientists target specific sodium channel to prevent breast cancer

Antiviral agent protects rhesus monkeys from deadly Ebola virus

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Glycan binding proteins modify parasite infection in cells of the heart muscle

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

UConn researchers sequence RNA of most complicated gene

YK-4-279 compound works against some forms of leukemia: Study

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Physicists use diamonds to detect early-stage cancerous tumours

Scientists can now use skin samples from older patients to grow brain cells

Scientists engineer stem cells to better understand mechanisms behind leukemia

Artificial lung model could provide better understanding of health risks associated with airborne pollution

Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

HDL not so good in protecting women against atherosclerosis, study shows

Scientists map EGFRvIII mutant that causes brain cancer

Gene therapy prevents neuronal death, disease effects in experimental model of PD

Leading experts to discuss role of laboratory medicine in personalized medicine

Father’s life experiences can affect health, development of both children and grandchildren

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

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