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Study sheds light on genetic differences between colorectal cancer in older and younger patients

While the overall rate of colorectal cancer (CRC) is declining, CRC specifically among young patients is increasing. Previous studies have shown that CRC in patients younger than 50 years old tends to be more aggressive than CRC in older patients.

29 May 2015

MIT, UCSD researchers use probiotics to detect cancer in the liver

Engineers at MIT and the University of California at San Diego have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics — beneficial bacteria similar to those found in yogurt.

29 May 2015

Larger studies needed to validate multigene testing for prediction of breast cancer risk

While advances in technology have made multigene testing, or "panel testing," for genetic mutations that increase the risk of breast or other cancers an option, authors of a review published today in the New England Journal of Medicine say larger studies are needed in order to provide reliable risk estimates for counseling these patients.

29 May 2015

Study expands understanding of the production of ET-743 compound

For decades, scientists have known that ET-743, a compound extracted from a marine invertebrate called a mangrove tunicate, can kill cancer cells. The drug has been approved for use in patients in Europe and is in clinical trials in the U.S.

29 May 2015

Scientists reveal why lone kidney gets bigger when the other one is lost

Scientists have found an explanation for the century-old observation that if you end up with just one kidney, the lone organ gets bigger.

29 May 2015

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.

29 May 2015

New TB-Profiler tool to find appropriate drugs for TB patients may improve likelihood of cure

Finding out what drugs can be used to treat a patient with tuberculosis (TB) can be sped up by days or weeks, thanks to a new free online tool. The new TB-Profiler tool, developed by a team of scientists led by Dr Taane Clark at the London School of Hygiene & Tropical Medicine, analyses and interprets genome sequence data to predict resistance to 11 drugs used for the treatment of TB.

29 May 2015

Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

Amgen today announced the creation of a catalog of qualified tools and reagents available to academic institutions to help further research and advance basic discoveries in biology, as well as deepen relationships with academic institutions.

29 May 2015

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

The largest complete DNA analysis of ovarian cancer in the world, published overnight in Nature, has revealed unprecedented new insight into the genetic twists and turns a deadly form of the disease takes to outsmart chemotherapy, potentially changing treatment approaches for women around the world.

29 May 2015

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Duke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).

29 May 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

MIT researchers find neural circuit that appears to cause decision-making in approach-avoidance conflict

Some decisions arouse far more anxiety than others. Among the most anxiety-provoking are those that involve options with both positive and negative elements, such choosing to take a higher-paying job in a city far from family and friends, versus choosing to stay put with less pay.

29 May 2015

Researchers find weak spot in some antibiotic-resistant bacteria

Using a complex modeling program that helps analyze the physical dynamics of large, structurally complex protein molecules, a research team has made progress towards finding a weak spot in the architecture of a group of enzymes that are essential to antibiotic resistance in a number of bacteria.

29 May 2015

Investigating epigenetic marks in ancient DNA could help understand health of ancient populations

A new study by anthropologists from The University of Texas at Austin shows for the first time that epigenetic marks on DNA can be detected in a large number of ancient human remains, which may lead to further understanding about the effects of famine and disease in the ancient world.

29 May 2015

Therapy for genetically-caused emphysema slows progression of lung disease

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

Surprising link found between creative problem-solving and increased activity in the cerebellum

Investigators at Stanford University have found a surprising link between creative problem-solving and heightened activity in the cerebellum, a structure located in the back of the brain and more typically thought of as the body's movement-coordination center.

29 May 2015

Impulsive behavior could put you at risk for binge eating

Do you get impulsive when you're upset? If so, this could be putting you at risk for binge eating. According to Kelly Klump, professor of psychology at Michigan State University and senior author, the more impulsive you are, the more likely it is you'll binge eat when experiencing negative feelings.

29 May 2015

Proteomics research market estimated to reach $1.6 billion this year

Pharmaceutical companies and diagnostics companies spend billions developing new drugs and tests, and this is translating into a sizeable market for the instruments that can assist them. This according to Kalorama Information, a healthcare market research publisher. Kalorama Information said instruments such as mass spectrometry, electrophoresis and liquid chromatography that can assist in the identification of drug targets and the validation of biomarkers, are in demand.

29 May 2015

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS).

28 May 2015

Medical Science News

Study sheds light on genetic differences between colorectal cancer in older and younger patients

MIT, UCSD researchers use probiotics to detect cancer in the liver

Larger studies needed to validate multigene testing for prediction of breast cancer risk

Study expands understanding of the production of ET-743 compound

Scientists reveal why lone kidney gets bigger when the other one is lost

Differences in brain expression of RORA protein levels may lead to sex bias in autism

New TB-Profiler tool to find appropriate drugs for TB patients may improve likelihood of cure

Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

MIT researchers find neural circuit that appears to cause decision-making in approach-avoidance conflict

Researchers find weak spot in some antibiotic-resistant bacteria

Investigating epigenetic marks in ancient DNA could help understand health of ancient populations

Therapy for genetically-caused emphysema slows progression of lung disease

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Surprising link found between creative problem-solving and increased activity in the cerebellum

Impulsive behavior could put you at risk for binge eating

Proteomics research market estimated to reach $1.6 billion this year

Novel discovery offers new insight into why women more likely than men to develop MS

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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