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Ligand Pharmaceuticals announces data from LG-7501 preclinical studies on HCV

Ligand Pharmaceuticals Incorporated announced that data from preclinical studies evaluating LG-7501 were featured in a poster presentation today at the 63rd Annual Meeting of the American Association for the Study of Liver Diseases in Boston.

14 Nov 2012

Patients with gastric cancer have impaired TGFβig-h3 protein

Scientists at the University of Liverpool have found that the production of a protein that prevents the growth and spread of cancerous cells is impaired in patients with gastric cancer.

14 Nov 2012

Study indicates that impact of early-life abuse extend well into older age

The psychological scars of childhood abuse can last well into adulthood. New research from Concordia University shows the harm can have longterm negative physical effects, as well as emotional ones.

14 Nov 2012

Atpif1 gene regulates heme synthesis in red blood cell formation

Scientists at the University of Georgia, Harvard Medical School and the University of Utah have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood.

14 Nov 2012

Neuroticism can be good for health under certain circumstances

Under certain circumstances neuroticism can be good for your health, according to a University of Rochester Medical Center study showing that some self-described neurotics also tended to have the lowest levels of Interleukin 6 (IL-6), a biomarker for inflammation and chronic disease.

14 Nov 2012

UCI study reveals novel immune system response to bacterial infections

UC Irvine biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.

14 Nov 2012

Scientists discover how external signals regulate vascular remodelling at cell level

Blood vessels are extremely dynamic: depending on the external conditions, they can adapt their permeability for nutrients, their contractility, and even their shape. Unlike cardiac muscle cells, for example, the smooth muscle cells in blood vessels demonstrate a high degree of plasticity, so they can specialise or multiply as required, even repairing damage to the vessel wall.

13 Nov 2012

Cancer metastasis research facilitated by nanoparticle characterization technology from NanoSight

NanoSight, leading manufacturers of unique nanoparticle characterization technology, reports on the breakthrough cancer metastasis research of Dr. Hector Peinado Selgas and Dr. David Lyden's research team from Weill Cornell Medical College.

13 Nov 2012

Could lactate levels in amniotic fluid help diagnose dysfunctional labour?

With as many as a 30 percent of pregnant women in Australia experiencing a caesarean birth, a study led by researchers from the University of Sydney aims to determine if there is a link between high levels of lactate in amniotic fluid and difficult labours which may end with a caesarean section.

13 Nov 2012

New vaccines and drug treatments urgently needed for bacterial meningitis

New vaccines and drug treatments are urgently needed for bacterial meningitis, a devastating disease which kills or maims around a fifth of people who contract it, according to medical experts writing in a new Series on bacterial meningitis, published in The Lancet.

9 Nov 2012

Dream images could provide insights into people's mental health problems

Dream images could provide insights into people's mental health problems and may help with their treatment, according to a psychology researcher from the University of Adelaide.

9 Nov 2012

University of Leicester scientists identify unique forms of spinal nerve activity

Scientists from the University of Leicester have hit upon unique forms of spinal nerve activity that shape output of nerve cell networks controlling motor behaviours.

9 Nov 2012

Autism Speaks releases biological and clinical data from 383 new AGRE families

Autism Speaks, the world's leading autism science and advocacy organization, is proud to announce the release of biological and clinical data from 383 new families participating in Autism Speaks Autism Genetic Resource Exchange (AGRE) to researchers. AGRE is a resource for scientists that is comprised of clinical and biological data from families who have two or more children on the autism spectrum.

9 Nov 2012

ACT announces results from three ongoing stem cell clinical trials for macular degeneration

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today that its upcoming conference call on its third quarter financial results will also provide some representative examples of data being collected from patients in its clinical trials for forms of macular degeneration.

9 Nov 2012

Longer looks: People with mental disabilities have a vote; Genome sequencing raises hope - also anxiety

I may get Alzheimer's disease, I was told after getting my DNA analyzed. I could suffer the consequences of an abnormal blood clot in my heart or my brain. Or perhaps I'll suffer from a disease called primary myelofibrosis that's caused by an overactive bone marrow. All of these were possible outcomes, based on my genetic profile. In each case, the test only gives an increased risk for disease, not a definitive diagnosis.

9 Nov 2012

Respiratory symptoms differ significantly during different stages of the menstrual cycle

Respiratory symptoms vary significantly during different stages of the menstrual cycle, with higher frequencies during the mid-luteal to mid-follicular stages, according to a new study.

9 Nov 2012

Patients with focal segmental glomerulosclerosis tend to have high suPAR levels

Patients with a disease that is a leading cause of kidney failure tend to have high levels of a particular factor circulating in their blood, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

9 Nov 2012

Genetic ancestry may exacerbate asthma among African American males

African American males are among those at greatest risk for severe asthma attacks. In a new study presented at the American College of Allergy, Asthma and Immunology's (ACAAI) Annual Scientific Meeting in Anaheim, Calif. Nov. 8-13, researchers assessed the relationship between genetic ancestry and severe asthma.

9 Nov 2012

Inactivating beta2 subunit of nicotinic receptors may help smokers quit without feeling anxious

Preclinical data suggests inactivation of a specific sub-class of nicotinic receptors may be an effective strategy to help smokers quit without feeling anxious, according to Virginia Commonwealth University researchers.

9 Nov 2012

Dopamine improves long-term memory

The feel-good hormone dopamine improves long-term memory. This is the finding of a team lead by Emrah D-zel, neuroscientist at the German Center for Neurodegenerative Diseases and the University of Magdeburg.

9 Nov 2012