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Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Disruption of brain developmental processes caused by premature birth can affect cognitive function

Researchers from King's College London have for the first time used a novel form of MRI to identify crucial developmental processes in the brain that are vulnerable to the effects of premature birth.

21 May 2013

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

A novel vaccine study from South Dakota State University will headline the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' National Biotechnology Conference.

21 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

UTMB researchers awarded grant to study gene therapy techniques to eliminate neuropathic pain

University of Texas Medical Branch at Galveston researchers have been awarded a five-year, $1.8 million grant by the National Institute of Neurological Disorders and Stroke to apply the techniques of gene therapy to the problem of neuropathic pain - that is, pain that arises from a malfunction in the nervous system.

21 May 2013

Scientists design 'fishing' technique to show health benefits of foods

New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death.

21 May 2013

Genetic markers improve detection of individuals with high risk for CHD

The study comprised over 24,000 Finnish subjects and was led by Professor Samuli Ripatti. The results revealed that a panel of 28 genetic markers improved detection of individuals with high risk for coronary heart disease (10-year risk ≥20%) over traditional risk factors.

21 May 2013

Researchers pinpoint catalytic trigger for onset of Alzheimer's disease

Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease - when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons in the brain.

21 May 2013

New breakthrough in progeria treatment

Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy, University of Gothenburg, Sweden, indicates that the development of progeria in mice was inhibited upon reducing the production of this enzyme.

21 May 2013

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

20 May 2013

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

A new measure of the heterogeneity - the variety of genetic mutations - of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer.

20 May 2013

Targeting glucagon action: A new frontier for regulating diabetes

For the first time, scientists at the Toronto General Research Institute showed that targeting glucagon action in the brain may be a new frontier for regulating diabetes.

20 May 2013

Promising method to distinguish pancreatic cancer from chronic pancreatitis

Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis - two disorders that are difficult to tell apart. A molecular marker obtained from pancreatic "juices" can identify almost all cases of pancreatic cancer, their study shows.

20 May 2013

Joint replacement surgery might be avoidable in the future, suggest scientists

Scientists at Johns Hopkins have turned their view of osteoarthritis inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage.

20 May 2013

Certain varieties of clay have ability to kill MRSA, says ASU researcher

In the race to protect society from infectious microbes, the bugs are outrunning us. The need for new therapeutic agents is acute, given the emergence of novel pathogens as well as old foes bearing heightened antibiotic resistance.

20 May 2013

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

An exploration of electronic "screen time" and sleep on mood, memory and learning was given the top Addiction Science Award at the 2013 Intel International Science and Engineering Fair - the world's largest science competition for high school students.

20 May 2013

Researchers examine new zinc-based bioabsorbable stents

In 2012, more than 3 million people had stents inserted in their coronary arteries. These tiny mesh tubes prop open blood vessels healing from procedures like a balloon angioplasty, which widens arteries blocked by clots or plaque deposits. After about six months, most damaged arteries are healed and stay open on their own. The stent, however, is there for a lifetime.

20 May 2013

Keystone molecules in chemical communication, defense have dominant consequences in nature

Naturally occurring "keystone" molecules that have powerful behavioral effects on diverse organisms often play large but unrecognized roles in structuring ecosystems, according to a theory proposed in the June issue of BioScience.

20 May 2013

Non-invasive brain stimulation techniques improve memory

Non-invasive brain stimulation techniques aimed at mental and neurological conditions include transcranial magnetic stimulation for depression, and transcranial direct current (electrical) stimulation, shown to improve memory.

20 May 2013

Understanding the role of dsRNA in antiviral host defense systems

Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of double-stranded RNA, often produced when a virus invades a host cell.

20 May 2013

Medical Science News

Researchers develop new mouse model to discover gene pathways that drive MPNST

Disruption of brain developmental processes caused by premature birth can affect cognitive function

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

Researchers identify novel biomarkers for predicting mortality in ICU patients

UTMB researchers awarded grant to study gene therapy techniques to eliminate neuropathic pain

Scientists design 'fishing' technique to show health benefits of foods

Genetic markers improve detection of individuals with high risk for CHD

Researchers pinpoint catalytic trigger for onset of Alzheimer's disease

New breakthrough in progeria treatment

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Measuring genetic diversity within tumor predicts outcomes of patients with head and neck cancer

Targeting glucagon action: A new frontier for regulating diabetes

Promising method to distinguish pancreatic cancer from chronic pancreatitis

Joint replacement surgery might be avoidable in the future, suggest scientists

Certain varieties of clay have ability to kill MRSA, says ASU researcher

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

Researchers examine new zinc-based bioabsorbable stents

Keystone molecules in chemical communication, defense have dominant consequences in nature

Non-invasive brain stimulation techniques improve memory

Understanding the role of dsRNA in antiviral host defense systems

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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