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Researchers develop new tool for comprehensive mapping of cell-cell communication

Researchers at Memorial Sloan-Kettering Cancer Center, together with collaborators in Germany, have developed a new method for identifying the cell of origin of intracellular and secreted proteins within multicellular environments.

11 Jul 2013

New concept could improve cancer drug delivery

Researchers have developed a concept to potentially improve delivery of drugs for cancer treatment using nanoparticles that concentrate and expand in the presence of higher acidity found in tumor cells.

11 Jul 2013

Microparticle technique offers better control over kinetics of cell differentiation

Before scientists and engineers can realize the dream of using stem cells to create replacements for worn out organs and battle damaged body parts, they'll have to develop ways to grow complex three-dimensional structures in large volumes and at costs that won't bankrupt health care systems.

11 Jul 2013

Children diagnosed with autism have excessive cerebrospinal fluid and enlarged brains in infancy

Children who were later diagnosed with autism spectrum disorder had excessive cerebrospinal fluid and enlarged brains in infancy, a study by a multidisciplinary team of researchers with the UC Davis MIND Institute has found, raising the possibility that those brain anomalies may serve as potential biomarkers for the early identification of the neurodevelopmental disorder.

11 Jul 2013

Study links vitamin D deficiency to accelerated aging of bones

Everyone knows that as we grow older our bones become more fragile. Now a team of U.S. and German scientists led by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley has shown that this bone-aging process can be significantly accelerated through deficiency of vitamin D - the sunshine vitamin.

11 Jul 2013

Advanced genetics technologies may help predict patient outcomes in people with ALL

New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately predict patient outcomes for patients with a particularly aggressive form of acute lymphocytic leukemia (ALL).

10 Jul 2013

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

University of British Columbia researchers have developed a vaccine that may halt the spread of West Nile Virus among common and endangered bird species.

10 Jul 2013

Research finding may offer novel path for cancer drug design

Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.

10 Jul 2013

Study confirms role of MAPK mutations in pilocytic astrocytomas

Brain cancer is the primary cause of cancer mortality in children. Even in cases when the cancer is cured, young patients suffer from the stress of a treatment that can be harmful to the developing brain. In a search for new target structures that would create more gentle treatments, cancer researchers are systematically analyzing all alterations in the genetic material of these tumors.

10 Jul 2013

New approach delivers RNA drugs to silence malfunctioning genes

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which are used to inhibit gene expression. The drugs, in essence, mimic a natural process called RNA interference.

10 Jul 2013

RUB chemists track interaction of enkephalin messengers with opioid receptor

"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, and opioid receptors is very difficult to study.

10 Jul 2013

Rising unemployment rates stop upward trend of fertility in European countries

The largest effect was seen in young adults. Europeans under the age of 25 have especially refrained from having children in the face of rising unemployment rates. The drop of children per woman was strongest for first births. That means, over the last decade young Europeans have particularly postponed family formation.

10 Jul 2013

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

In the constant cross talk between our brain and our gut, two gut hormones are already known to tell the brain when we have had enough to eat. New research suggests that boosting levels of these hormones simultaneously may be an effective new weapon in the fight against obesity.

10 Jul 2013

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.

10 Jul 2013

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile - established when it afflicted the New York Yankees' Lou Gehrig - ALS remains a disease that scientists are unable to predict, prevent, or cure.

10 Jul 2013

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

FORMA Therapeutics and Cancer Research Technology, Ltd., the commercialization company of Cancer Research UK, announced today a bold research initiative to discover innovative tools, technologies and therapeutic drug candidates against a variety of protein homeostasis regulators called, deubiquitinating enzymes.

9 Jul 2013

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

A study by researchers at Neuroscience Research Australia (NeuRA) is the first to demonstrate that patients with frontotemporal dementia (FTD) lose the emotional content/colour of their memories. These findings explain why FTD patients may not vividly remember an emotionally charged event like a wedding or funeral.

9 Jul 2013

Key metabolites in blood could provide clues to long-term overall health and ageing

Scientists have found that key metabolites in blood - chemical 'fingerprints' left behind as a result of early molecular changes before birth or in infancy - could provide clues to a person's long-term overall health and rate of ageing in later life.

9 Jul 2013

Physicians have new resource for managing disease in patients with early-stage breast cancer

Physicians have a new resource for managing disease in patients with early-stage breast cancer. Patients diagnosed with ductal carcinoma in situ -- cancer that has not left the breast ducts -- now have the benefit of a multi-gene analysis that considers gene patterns to individualize therapy and determine the chance for recurrence, potentially sparing the patient additional therapy.

9 Jul 2013

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

9 Jul 2013

Medical Science News

Researchers develop new tool for comprehensive mapping of cell-cell communication

New concept could improve cancer drug delivery

Microparticle technique offers better control over kinetics of cell differentiation

Children diagnosed with autism have excessive cerebrospinal fluid and enlarged brains in infancy

Study links vitamin D deficiency to accelerated aging of bones

Advanced genetics technologies may help predict patient outcomes in people with ALL

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

Research finding may offer novel path for cancer drug design

Study confirms role of MAPK mutations in pilocytic astrocytomas

New approach delivers RNA drugs to silence malfunctioning genes

RUB chemists track interaction of enkephalin messengers with opioid receptor

Rising unemployment rates stop upward trend of fertility in European countries

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

Study shows disrupted micronuclei may prove to be a valuable tool for detecting cancer

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

Key metabolites in blood could provide clues to long-term overall health and ageing

Physicians have new resource for managing disease in patients with early-stage breast cancer

Disrupted micronuclei might play more active role in carcinogenesis, new study finds

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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