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Nature journal publishes Ember's brown fat biology data

Ember Therapeutics, Inc., a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key data supporting its lead brown fat biology program in the journal Nature.

12 Jan 2012

Elevated ISG15 pathway may provide therapeutic targets for breast cancer

Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and is the subject of a study published in the January 2012 issue of Experimental Biology and Medicine.

12 Jan 2012

New imaging agent shows promise in detecting signs of AD

Scientists are reporting development and initial laboratory tests of an imaging agent that shows promise for detecting the tell-tale signs of Alzheimer's disease (AD) in the brain - signs that now can't confirm a diagnosis until after patients have died.

12 Jan 2012

Novel avenues to treat heart attack

Novel avenues to treat a heart attack: in patients, who have a blood pressure cuff several times briefly inflated before they undergo coronary artery surgery with cardiopulmonary bypass, the heart is protected from damage.

12 Jan 2012

Chemotherapy drugs can lead to relapse of leukemia

The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.

12 Jan 2012

Scientists identify rare genetic mutation linked to prostate cancer

After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease.

12 Jan 2012

St. Jude introduces 'Explore' website for pediatric genome project

St. Jude Children's Research Hospital has launched a freely available website for published research results from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP). The PCGP is the largest effort to date aimed at sequencing the entire genomes of both normal and cancer cells from pediatric cancer patients, comparing differences in the DNA to identify genetic mistakes that lead to childhood cancers.

12 Jan 2012

Scientists explain why coffee drinkers show lower risk of Type 2 diabetes

Why do heavy coffee drinkers have a lower risk of developing Type 2 diabetes, a disease on the increase around the world that can lead to serious health problems? Scientists are offering a new solution to that long-standing mystery in a report in ACS' Journal of Agricultural & Food Chemistry.

12 Jan 2012

Omega-3 can protect nerves from injury and help them to regenerate

Research from Queen Mary, University of London suggests that omega-3 fatty acids, which are found in fish oil, have the potential to protect nerves from injury and help them to regenerate.

12 Jan 2012

Spherix completes SPX-106 28-day rat toxicology study

Spherix Incorporated – an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and provider of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today reported the successful completion of its 28-day rat toxicology study of its drug candidate, SPX-106.

11 Jan 2012

Researchers identify mechanism that makes retinoblastoma so aggressive

New findings from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) have helped identify the mechanism that makes the childhood eye tumor retinoblastoma so aggressive. The discovery explains why the tumor develops so rapidly while other cancers can take years or even decades to form.

11 Jan 2012

Scientists investigate specific role of IT neurons in 3D perception

The incredible ability of our brain to create a three-dimensional (3D) representation from an object's two-dimensional projection on the retina is something that we may take for granted, but the process is not well understood and is likely to be highly complex. Now, new research published by Cell Press in the January 12 issue of the journal Neuron provides the first direct evidence that specific brain areas underlie perception of different 3D structures and sheds light the way that the primate brain reconstructs real-world objects.

11 Jan 2012

Research into ground-breaking treatment for bowel cancer

Research into a ground-breaking treatment for bowel cancer at Queen's University Belfast has received a massive funding boost from Cancer Research UK.

11 Jan 2012

Researchers study fusion plasmas to understand fast dynamics of networks in the human brain

Fusion plasma researchers at the University of Warwick have teamed up with Cambridge neuroscientists to apply their expertise developed to study inaccessible fusion plasmas in order to significantly improve the understanding of the data obtained from non-invasive study of the fast dynamics of networks in the human brain.

11 Jan 2012

Researchers analyze microorganisms in human gut as a complex, integrated biological system

For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight.

11 Jan 2012

Findings on cell working could lead to test and therapy for kidney failure caused by E. coli

New findings by St. Michael's researchers about the way cells work could lead to a test and therapy for kidney failure caused by E. coli

11 Jan 2012

Chemical preservative in cosmetics can interrupt neurological development

Scientists, health officials, and manufacturers already know that a chemical preservative found in some products, including cosmetics, is harmful to people and animals in high concentrations, but a new Brown University study in tadpoles reports that it can also interrupt neurological development even in very low concentrations.

11 Jan 2012

Novel nanosensors can lead to fewer experiments on animals

Countless mice, rats and rabbits die every year in the name of science - and the situation is getting worse. While German laboratories used some 2.41 million animals for scientific research in 2005, by 2009 this number had grown to 2.79 million. One third were destined for fundamental biology research, and the majority were used for researching diseases and developing medical compounds and devices.

11 Jan 2012

Inhibiting glutaminase can curb growth of B cell cancers

Cancer cells have been long known to have a "sweet tooth," using vast amounts of glucose for energy and for building blocks for cell replication.

11 Jan 2012

Intestinal worm infections may not be bad

Intestinal worm infections may not be all bad, according to a new study by William C. Gause, PhD, and colleagues at UMDNJ- New Jersey Medical School. The researchers have found cytokines that help oust intestinal worm infections in mice also soothe associated lung injury and inflammation.

11 Jan 2012