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Scientists identify TDO enzyme as new target for cancer therapy

Scientists from the Ludwig Institute for Cancer Research (LICR) in Brussels identified a new target for cancer therapy, an enzyme which prevents the immune system from recognizing and destroying certain types of tumors.

1 Feb 2012

Kras gene plays a role in continuous growth of pancreatic cancer

A mutant protein found in nearly all pancreatic cancers plays a role not only in the cancer's development but in its continued growth, according to a new study from University of Michigan Comprehensive Cancer Center researchers. The finding suggests a possible target for developing new ways to treat this deadly disease.

1 Feb 2012

Pneumonic plague bacteria transform lungs into a playground for microbes to flourish

Among medical mysteries baffling many infectious disease experts is exactly how the deadly pneumonic plague bacterium, Yersinia pestis, goes undetected in the first few day of lung infection, often until it's too late for medical treatment.

1 Feb 2012

Nanosize titanates may inhibit growth of oral cancer and bacterial cell lines

Sometimes bigger isn't better. Researchers at the U.S. Department of Energy's Savannah River National Laboratory have successfully shown that they can replace useful little particles of monosodium titanate (MST) with even tinier nano-sized particles, making them even more useful for a variety of applications.

1 Feb 2012

New technology helps scientists observe Parkinson's cell development

In the US alone, at least 500,000 people suffer from Parkinson's disease, a neurological disorder that affects a person's ability to control his or her movement. New technology from the University of Bonn in Germany lets researchers observe the development of the brain cells responsible for the disease.

1 Feb 2012

Researchers investigate Avian Pathogenic E. coli strains

Escherichia coli bacteria thrive in the lower intestine of humans and other animals, including birds. Most are vital constituents of the healthy gut flora, but certain forms of E. coli cause a range of diseases in both humans and poultry.

1 Feb 2012

Fluorescence microscopy reveals 3-D picture of myoV's transport capacity

A new study in the Journal of General Physiology uses state-of-the-art fluorescence microscopy to provide a striking 3-D picture of how class V myosins (myoV) "walk" along their actin track.

1 Feb 2012

Link between maternal nurturing and size of hippocampus in healthy children

School-age children whose mothers nurtured them early in life have brains with a larger hippocampus, a key structure important to learning, memory and response to stress. The new research, by child psychiatrists and neuroscientists at Washington University School of Medicine in St. Louis, is the first to show that changes in this critical region of children's brain anatomy are linked to a mother's nurturing.

31 Jan 2012

Small molecules at the cell’s membrane enable cell movement

Cell biologists at Johns Hopkins have identified key steps in how certain molecules alter a cell’s skeletal shape and drive the cell’s movement.

31 Jan 2012

Study investigates trade-off between sperm quality and immunity

A new study shows the production of sperm is more biologically taxing than previously thought, and expending energy on it has significant health implications.

31 Jan 2012

Lycopene can kill prostate cancer cells

A nutrient in cooked tomatoes has been shown in laboratory studies to slow the growth of or even kill prostate cancer cells.

31 Jan 2012

HSP40/70 linked to hepatitis C infection

Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks viral replication, which can lead to liver cancer and cirrhosis.

31 Jan 2012

Study pinpoints genetic factors behind increased ALL risk in Hispanic children

Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children's Research Hospital scientists has pinpointed genetic factors behind the grim statistics.

31 Jan 2012

ISCB honors CMU professor with Overton Prize

The International Society for Computational Biology (ISCB) has awarded its Overton Prize for outstanding accomplishment to Ziv Bar-Joseph, associate professor in Carnegie Mellon University's Lane Center for Computational Biology and Machine Learning Department.

31 Jan 2012

GRANITE program to aid in development of new TB fighting methods

A Rutgers-Camden professor is using his expertise in computer science to aid in the development of new methods to fight tuberculosis.

31 Jan 2012

Engineers discover electrical property in arteries

The heart's inner workings are mysterious, perhaps even more so with a new finding. Engineers at the University of Washington have discovered an electrical property in arteries not seen before in mammalian tissues.

31 Jan 2012

Pannexin1 protein may play an important role in mechanics of tumors

By studying tumor cell behavior in a novel "scaffold-free" 3-D system, researchers have determined that the protein Pannexin1 may play an important biomechanical role in binding tissues together, an effect that is lost in cancerous cells.

31 Jan 2012

MT2 gene mutations may increase risk of diabetes

Researchers in Lille and Paris demonstrated that mutations in the melatonin receptor gene (melatonin or the "hormone of darkness" induces sleep) lead to an almost sevenfold increase in the risk of developing diabetes.

31 Jan 2012

Researchers decipher genetic material of 48 pediatric glioblastomas

Glioblastomas grow extremely aggressively into healthy brain tissue and, moreover, are highly resistant to radiation therapy and chemotherapy. Therefore, they are regarded as the most malignant type of brain tumor. Currently available treatment methods are frequently not very effective against this type of cancer. Glioblastoma can affect people of all ages, but is less common in children than in adults.

31 Jan 2012

Research advances understanding of hypoxic response

A new family of proteins which regulate the human body's 'hypoxic response' to low levels of oxygen has been discovered by scientists at Barts Cancer Institute at Queen Mary, University of London and The University of Nottingham.

30 Jan 2012