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Gladstone Senior Investigator named AAAS fellow for cardiac and stem cell research

The American Association for the Advancement of Science (AAAS) has named Gladstone Senior Investigator Deepak Srivastava, MD, a Fellow for his efforts to advance science and its applications.

17 Dec 2011

Microvascular stamp stimulates, directs blood vessel growth on wound surface

Researchers have developed a bandage that stimulates and directs blood vessel growth on the surface of a wound. The bandage, called a "microvascular stamp," contains living cells that deliver growth factors to damaged tissues in a defined pattern. After a week, the pattern of the stamp "is written in blood vessels," the researchers report.

16 Dec 2011

F. nucleatum alters endothelial integrity and allows other bacteria to invade human body

A common oral bacteria, Fusobacterium nucleatum, acts like a key to open a door in human blood vessels and leads the way for it and other bacteria like Escherichia coli to invade the body through the blood and make people sick, according to dental researchers at Case Western Reserve University.

16 Dec 2011

Researchers discover how the brain merges sights and sounds

In order to get a better picture of our surroundings, the brain has to integrate information from different senses, but how does it know which signals to combine? New research involving scientists from the Max Planck Institute for Biological Cybernetics, the Bernstein Center for Computational Neuroscience T-bingen, the University of Oxford, and the University of Bielefeld has demonstrated that humans exploit the correlation between the temporal structures of signals to decide which of them to combine and which to keep segregated.

16 Dec 2011

Short spiral-shaped proteins can efficiently deliver DNA segments to cells

Clinical gene therapy may be one step closer, thanks to a new twist on an old class of molecules. A group of University of Illinois researchers, led by professors Jianjun Cheng and Fei Wang, have demonstrated that short spiral-shaped proteins can efficiently deliver DNA segments to cells. The team published its work in the journal Angewandte Chemie.

16 Dec 2011

Certain measures of kidney health may predict who is likely to die prematurely

Certain measures of kidney health may predict who is likely to die prematurely, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

16 Dec 2011

Researchers identify gene responsible for EMT transformation

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells -which group together and are static- losing adhesion and moving towards a new site.

16 Dec 2011

Scientists identify how cells reduce tissue damage from inflammation in ALI model

Researchers at the University of Illinois at Chicago College of Medicine have found in an animal model of acute lung injury a molecular mechanism that allows cells of the immune system to reduce tissue damage from inflammation.

16 Dec 2011

Gates Foundation, Grand Challenges to develop new diagnostics for tropical diseases

Grand Challenges Canada and the Bill & Melinda Gates Foundation have teamed up on an unprecedented global effort to discover and develop affordable, easy-to-use tools to help developing country health workers rapidly diagnose diseases in rural communities. The expected result: more timely and appropriate treatment of illnesses in poor countries, potentially saving countless lives.

16 Dec 2011

Wistar to develop new drug against EBV-associated cancers

The Wistar Institute today announced that it has signed a funding agreement with the Wellcome Trust, a United Kingdom-based charity, to support the development of a new drug to treat cancers associated with Epstein-Barr virus.

16 Dec 2011

Study unveils mechanisms behind neurological effects of penitrem A

The mould fungus Penicillium crustosum occurs relatively frequently in food and animal fodder stored in temperate conditions. This mould produces powerful neurotoxins, for example penitrem A, which causes symptoms that are difficult to distinguish from those of other neurological diseases.

16 Dec 2011

Hereditary cancer syndrome predisposes patients to uveal melanoma

Ohio State University researchers have discovered a hereditary cancer syndrome that predisposes certain people to a melanoma of the eye, along with lung cancer, brain cancer and possibly other types of cancer.

16 Dec 2011

Researchers identify second oldest human disease mutation

A new study has identified a gene mutation that researchers estimate dates back to 11,600 B.C., making it the second oldest human disease mutation yet discovered.

16 Dec 2011

Cancer-causing potential of fetal exposure to carcinogens can vary substantially

The cancer-causing potential of fetal exposure to carcinogens can vary substantially, a recent study suggests, causing different types of problems much later in life depending on the stage of pregnancy when the fetus is exposed.

16 Dec 2011

FLI, IZW partner to begin ageing research project in 2012

Jena`s Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI) and Berlin`s Leibniz Institute for Zoo and Wildlife Research (IZW) from Germany are jointly starting a project for ageing research in 2012.

16 Dec 2011

Scientists discover gene that causes Weaver syndrome

Scientists have found a gene that causes Weaver syndrome, a rare genetic disorder that typically causes large size at birth, tall stature, developmental delay during childhood, and intellectual disability.

16 Dec 2011

NACP and MAPT polymorphisms interact to influence rate of Parkinson's progression

Parkinson's disease is marked by the abnormal accumulation of α-synuclein and the early loss of dopamine neurons in the substantia nigra region of the brain. A polymorphism in the promotor of α-synuclein gene known as NACP-Rep1 has been implicated as a risk factor for the disease.

16 Dec 2011